Reactome | Ice2 [nucleoplasm]

Ice2 [nucleoplasm]

Stable Identifier

R-RNO-6807421

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

ICE2, D3ZIQ8

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Rattus norvegicus)

- RNA Polymerase II Transcription (Rattus norvegicus)
  - RNA polymerase II transcribes snRNA genes (Rattus norvegicus)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        LEC [nucleoplasm] (Rattus norvegicus)
        
        Ice2 [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        LEC [nucleoplasm] (Rattus norvegicus)
        
        Ice2 [nucleoplasm] (Rattus norvegicus)
    - Integrator complex processes the 3' end of snRNA (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        LEC [nucleoplasm] (Rattus norvegicus)
        
        Ice2 [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        LEC [nucleoplasm] (Rattus norvegicus)
        
        Ice2 [nucleoplasm] (Rattus norvegicus)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        LEC [nucleoplasm] (Rattus norvegicus)
        
        Ice2 [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        LEC [nucleoplasm] (Rattus norvegicus)
        
        Ice2 [nucleoplasm] (Rattus norvegicus)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Rattus norvegicus)
      - LEC [nucleoplasm] (Rattus norvegicus)
        
        Ice2 [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        LEC [nucleoplasm] (Rattus norvegicus)
        
        Ice2 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:D3ZIQ8

Gene Names

Ice2

Reference Genes

BioGPS Gene:691379 Ice2

ENSEMBL:ENSRNOG00000010160

ENSEMBL:ENSRNOG00000010160.8 Ice2

KEGG Gene (Rattus norvegicus):691379 Ice2

Monarch:691379 Ice2

NCBI Gene:691379 Ice2

UCSC:D3ZIQ8 Ice2

Reference Transcript

Other Identifiers

10911270

1393815_at

17845542

5638511

5646289

5649973

5683277

5708460

5715766

5900233

5934105

5947659

5983821

6148702

6160566

6175509

6210548

6272289

6294238

6497534

6518174

6520996

6583532

6592223

6619757

6726717

691379

A_44_P439073

A_44_P685298

A_64_P120856

GO:0000791

GO:0005634

GO:0005654

GO:0005694

GO:0005829

GO:0006351

GO:0006355

GO:0008023

GO:0015030

GO:0016073

GO:0016604

GO:0035363

GO:0042795

GO:0042796

GO:0043226

GO:0045945

PH_rn_0016878

PH_rn_0021610

Participates

as a component of

LEC [nucleoplasm] (Rattus norvegicus)

Inferred From

ICE2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001178037.1, XP_006243464.1

Ensembl

ENSRNOT00000013742, ENSRNOG00000010160, ENSRNOP00000013742

RGD

1585038