Reactome | Ints3 [nucleoplasm]

Ints3 [nucleoplasm]

Stable Identifier

R-RNO-6807435

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

INTS3, D3ZUT9

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Rattus norvegicus)

- RNA Polymerase II Transcription (Rattus norvegicus)
  - RNA polymerase II transcribes snRNA genes (Rattus norvegicus)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        Integrator [nucleoplasm] (Rattus norvegicus)
        
        Ints3 [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        Integrator [nucleoplasm] (Rattus norvegicus)
        
        Ints3 [nucleoplasm] (Rattus norvegicus)
    - Integrator complex processes the 3' end of snRNA (Rattus norvegicus)
      - Integrator [nucleoplasm] (Rattus norvegicus)
        
        Ints3 [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        Integrator [nucleoplasm] (Rattus norvegicus)
        
        Ints3 [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        Integrator [nucleoplasm] (Rattus norvegicus)
        
        Ints3 [nucleoplasm] (Rattus norvegicus)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        Integrator [nucleoplasm] (Rattus norvegicus)
        
        Ints3 [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        Integrator [nucleoplasm] (Rattus norvegicus)
        
        Ints3 [nucleoplasm] (Rattus norvegicus)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Rattus norvegicus)
      - Integrator [nucleoplasm] (Rattus norvegicus)
        
        Ints3 [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        Integrator [nucleoplasm] (Rattus norvegicus)
        
        Ints3 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:D3ZUT9

Gene Names

Ints3

Reference Genes

BioGPS Gene:361988 Ints3

ENSEMBL:ENSRNOG00000015153

Monarch:361988 Ints3

NCBI Gene:361988 Ints3

UCSC:D3ZUT9 Ints3

Reference Transcript

Other Identifiers

10824624

1388411_at

17749048

361988

5621756

5622006

5670827

5729565

5780344

5809074

5825645

5853219

5863349

5897365

6026896

6029420

6059100

6069964

6084578

6101768

6113945

6121048

6138304

6221880

6235559

6243634

6253897

6264222

6278229

6280372

6320807

6334236

6412438

6468999

6489792

6578223

6581992

6658755

6676063

6677944

A_42_P654166

A_64_P052435

GE1279904

GO:0000278

GO:0000724

GO:0005634

GO:0005694

GO:0005737

GO:0006281

GO:0006310

GO:0006974

GO:0010212

GO:0016073

GO:0016180

GO:0023052

GO:0032039

GO:0035861

GO:0043226

GO:0044818

GO:0070876

ILMN_1350103

PH_rn_0001209

PH_rn_0022999

rc_AI229674_at

Participates

as a component of

Integrator [nucleoplasm] (Rattus norvegicus)

Inferred From

INTS3 [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

ENSRNOP00000020575, ENSRNOT00000020575

RGD

1304593

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