Reactome | Rprd1a [nucleoplasm]

Rprd1a [nucleoplasm]

Stable Identifier

R-RNO-6814899

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

RPRD1A, D4AAU4

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Rattus norvegicus)

- RNA Polymerase II Transcription (Rattus norvegicus)
  - RNA polymerase II transcribes snRNA genes (Rattus norvegicus)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        Rprd1a [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        Rprd1a [nucleoplasm] (Rattus norvegicus)
    - Integrator complex processes the 3' end of snRNA (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        Rprd1a [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        Rprd1a [nucleoplasm] (Rattus norvegicus)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        Rprd1a [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        Rprd1a [nucleoplasm] (Rattus norvegicus)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        Rprd1a [nucleoplasm] (Rattus norvegicus)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RPRD1A,B:RPRD2:RPAP2 [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        Rprd1a [nucleoplasm] (Rattus norvegicus)
    - RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Rattus norvegicus)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RPRD1A,B:RPRD2:RPAP2 [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        Rprd1a [nucleoplasm] (Rattus norvegicus)
      - RPRD1A,B:RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        Rprd1a [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:D4AAU4

Gene Names

Rprd1a

Reference Genes

BioGPS Gene:291736 Rprd1a

ENSEMBL:ENSRNOG00000016036

ENSEMBL:ENSRNOG00000016036.8 Rprd1a

KEGG Gene (Rattus norvegicus):291736 Rprd1a

Monarch:291736 Rprd1a

NCBI Gene:291736 Rprd1a

UCSC:D4AAU4 Rprd1a

Reference Transcript

Other Identifiers

10803511

1372192_at

1386846_at

17725171

291736

5691150

5813514

5866389

5911631

6137984

6175274

6334577

6371942

6375607

6511375

6517917

6727459

A_44_P328489

A_44_P611921

A_44_P853167

GE1216067

GE1305171

GE14129

GO:0001111

GO:0005634

GO:0006351

GO:0043226

GO:0097550

ILMN_1371852

PH_rn_0017707

PH_rn_0018885

rc_AI145385_at

Participates

as a member of

RPRD1A,B [nucleoplasm] (Rattus norvegicus)

Inferred From

RPRD1A [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_214609.6, NP_001292108.1

Ensembl

ENSRNOP00000021624, ENSRNOT00000021624, ENSRNOG00000016036

RGD

1307374

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