Reactome | Rpl34-ps1 [cytosol]

Rpl34-ps1 [cytosol]

Stable Identifier

R-RNO-72458

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

RPL34, D4A4W9

Locations in the PathwayBrowser

Expand all

Metabolism of RNA (Rattus norvegicus)

- Nonsense-Mediated Decay (NMD) (Rattus norvegicus)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Rattus norvegicus)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Rattus norvegicus)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rpl34-ps1 [cytosol] (Rattus norvegicus)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rpl34-ps1 [cytosol] (Rattus norvegicus)
    - SMG6 hydrolyzes mRNA with premature termination codon (Rattus norvegicus)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rpl34-ps1 [cytosol] (Rattus norvegicus)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Rattus norvegicus)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rpl34-ps1 [cytosol] (Rattus norvegicus)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rpl34-ps1 [cytosol] (Rattus norvegicus)
    - p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Rattus norvegicus)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rpl34-ps1 [cytosol] (Rattus norvegicus)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rpl34-ps1 [cytosol] (Rattus norvegicus)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Rattus norvegicus)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Rattus norvegicus)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rpl34-ps1 [cytosol] (Rattus norvegicus)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rpl34-ps1 [cytosol] (Rattus norvegicus)
- rRNA processing (Rattus norvegicus)
  - rRNA processing in the nucleus and cytosol (Rattus norvegicus)
    - Major pathway of rRNA processing in the nucleolus and cytosol (Rattus norvegicus)
      - 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rpl34-ps1 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:D4A4W9

Gene Names

Rpl34-ps1

Reference Genes

ENSEMBL:ENSRNOG00000038045

ENSEMBL:ENSRNOG00000038045.5 Rpl34-ps1

Other Identifiers

10796416

10826818

1371761_at

17717113

6178334

6299581

6324981

6473503

6540554

A_64_P047893

GO:0003735

GO:0005198

GO:0005840

GO:0006412

GO:0043226

ILMN_1359707

PH_rn_0003289

rc_AI013910_at

Participates

as a component of

Inferred From

RPL34 [cytosol] (Homo sapiens)

Cross References

Ensembl

ENSRNOP00000054703, ENSRNOG00000038045, ENSRNOT00000057895

RGD

1309402, 1561086, 11502284

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