ATP binds to p2x7

Stable Identifier
R-RNO-877219
Type
Reaction [binding]
Species
Rattus norvegicus
Compartment
General
SVG |   | PPTX  | SBGN
ATP binds to p2x7

P2X7 is a receptor for extracellular ATP that acts as a ligand gated non-selective cation channel. It is also responsible for the ATP-dependent lysis of macrophages, which it brings about by mediating the formation of membrane pores permeable to large molecules (Adinolfi et al. 2005).

Literature References
PubMed ID Title Journal Year
8614837 The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)

Surprenant, A, Rassendren, F, Kawashima, E, North, RA, Buell, G

Science 1996
Participants
Orthologous Events
Authored
Reviewed
Created
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