p2x7 forms oligomeric non-selective cation channels

Stable Identifier
R-RNO-877248
Type
Reaction [binding]
Species
Rattus norvegicus
Compartment
plasma membrane
ReviewStatus
5/5
General
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p2x7 forms oligomeric non-selective cation channels
At low to intermediate concentrations of extracellular ATP, P2X4 and P2X7 probably function as heterotrimeric, reversible ATP-gated, non-desensitizing cation channels (Markwardt 2007).
Literature References
PubMed ID Title Journal Year
11313357 Differential assembly of rat purinergic P2X7 receptor in immune cells of the brain and periphery

Surprenant, A, Spelta, V, Kim, M, Sim, J, North, RA

J Biol Chem 2001
Participants
Input
Output
Orthologous Events
P2X7 forms oligomeric non-selective cation channels (Homo sapiens)
Authored
Jupe, S  (2011-04-15)
Reviewed
Kufer, TA  (2011-04-28)
Created
Jupe, S  (2010-06-11)
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