Reactome | THOC3 [nucleoplasm]

THOC3 [nucleoplasm]

Stable Identifier

R-RNO-8849121

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

B5DEY5

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Rattus norvegicus)

- RNA Polymerase II Transcription (Rattus norvegicus)
  - RNA Polymerase II Transcription Termination (Rattus norvegicus)
    - Cleavage of mRNA at the 3'-end (Rattus norvegicus)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Rattus norvegicus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Rattus norvegicus)
        
        THO complex [nucleoplasm] (Rattus norvegicus)
        
        THOC3 [nucleoplasm] (Rattus norvegicus)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Rattus norvegicus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Rattus norvegicus)
        
        THO complex [nucleoplasm] (Rattus norvegicus)
        
        THOC3 [nucleoplasm] (Rattus norvegicus)

Metabolism of RNA (Rattus norvegicus)

- Processing of Capped Intron-Containing Pre-mRNA (Rattus norvegicus)
  - Transport of Mature Transcript to Cytoplasm (Rattus norvegicus)
    - Transport of Mature mRNA derived from an Intron-Containing Transcript (Rattus norvegicus)
      - NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Rattus norvegicus)
        
        NXF1,2:NXT1::polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Rattus norvegicus)
        
        capped mRNA:CBC:EJC:TREX (minus DDX39B) [nucleoplasm] (Rattus norvegicus)
        
        TREX (minus DDX39B) [nucleoplasm] (Rattus norvegicus)
        
        THO complex [nucleoplasm] (Rattus norvegicus)
        
        THOC3 [nucleoplasm] (Rattus norvegicus)
        
        polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Rattus norvegicus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Rattus norvegicus)
        
        THO complex [nucleoplasm] (Rattus norvegicus)
        
        THOC3 [nucleoplasm] (Rattus norvegicus)
  - mRNA 3'-end processing (Rattus norvegicus)
    - Cleavage of mRNA at the 3'-end (Rattus norvegicus)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Rattus norvegicus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Rattus norvegicus)
        
        THO complex [nucleoplasm] (Rattus norvegicus)
        
        THOC3 [nucleoplasm] (Rattus norvegicus)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Rattus norvegicus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Rattus norvegicus)
        
        THO complex [nucleoplasm] (Rattus norvegicus)
        
        THOC3 [nucleoplasm] (Rattus norvegicus)
    - mRNA polyadenylation (Rattus norvegicus)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Rattus norvegicus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Rattus norvegicus)
        
        THO complex [nucleoplasm] (Rattus norvegicus)
        
        THOC3 [nucleoplasm] (Rattus norvegicus)
      - polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Rattus norvegicus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Rattus norvegicus)
        
        THO complex [nucleoplasm] (Rattus norvegicus)
        
        THOC3 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:B5DEY5

Reference Genes

BioGPS Gene:290519

ENSEMBL:ENSRNOG00000000104

ENSEMBL:ENSRNOG00000000104.6

KEGG Gene (Rattus norvegicus):290519

Monarch:290519

NCBI Gene:290519

UCSC:B5DEY5

Reference Transcript

RefSeq:NM_001106059.1

Other Identifiers

10794186

1379849_at

1380153_at

1390572_at

17714581

290519

5762147

5833579

5954243

5993945

6159113

6423980

6595651

6744533

A_42_P574411

A_44_P731793

A_64_P144417

GE1223523

GE1274462

GO:0005515

GO:0006406

GO:0006913

ILMN_1364764

PH_rn_0008500

Participates

as a component of

THO complex [nucleoplasm] (Rattus norvegicus)

Inferred From

THOC3 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001099529.1

Ensembl

ENSRNOG00000000104, ENSRNOT00000000116, ENSRNOP00000000116

RGD

1311669