Reactome | Thoc6 [nucleoplasm]

Thoc6 [nucleoplasm]

Stable Identifier

R-RNO-8849144

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

THOC6, Q6AY87

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Rattus norvegicus)

- RNA Polymerase II Transcription (Rattus norvegicus)
  - RNA Polymerase II Transcription Termination (Rattus norvegicus)
    - Cleavage of mRNA at the 3'-end (Rattus norvegicus)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Rattus norvegicus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Rattus norvegicus)
        
        THO complex [nucleoplasm] (Rattus norvegicus)
        
        Thoc6 [nucleoplasm] (Rattus norvegicus)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Rattus norvegicus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Rattus norvegicus)
        
        THO complex [nucleoplasm] (Rattus norvegicus)
        
        Thoc6 [nucleoplasm] (Rattus norvegicus)

Metabolism of RNA (Rattus norvegicus)

- Processing of Capped Intron-Containing Pre-mRNA (Rattus norvegicus)
  - Transport of Mature Transcript to Cytoplasm (Rattus norvegicus)
    - Transport of Mature mRNA derived from an Intron-Containing Transcript (Rattus norvegicus)
      - NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Rattus norvegicus)
        
        NXF1,2:NXT1::polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Rattus norvegicus)
        
        capped mRNA:CBC:EJC:TREX (minus DDX39B) [nucleoplasm] (Rattus norvegicus)
        
        TREX (minus DDX39B) [nucleoplasm] (Rattus norvegicus)
        
        THO complex [nucleoplasm] (Rattus norvegicus)
        
        Thoc6 [nucleoplasm] (Rattus norvegicus)
        
        polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Rattus norvegicus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Rattus norvegicus)
        
        THO complex [nucleoplasm] (Rattus norvegicus)
        
        Thoc6 [nucleoplasm] (Rattus norvegicus)
  - mRNA 3'-end processing (Rattus norvegicus)
    - Cleavage of mRNA at the 3'-end (Rattus norvegicus)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Rattus norvegicus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Rattus norvegicus)
        
        THO complex [nucleoplasm] (Rattus norvegicus)
        
        Thoc6 [nucleoplasm] (Rattus norvegicus)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Rattus norvegicus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Rattus norvegicus)
        
        THO complex [nucleoplasm] (Rattus norvegicus)
        
        Thoc6 [nucleoplasm] (Rattus norvegicus)
    - mRNA polyadenylation (Rattus norvegicus)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Rattus norvegicus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Rattus norvegicus)
        
        THO complex [nucleoplasm] (Rattus norvegicus)
        
        Thoc6 [nucleoplasm] (Rattus norvegicus)
      - polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Rattus norvegicus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Rattus norvegicus)
        
        THO complex [nucleoplasm] (Rattus norvegicus)
        
        Thoc6 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q6AY87

Gene Names

Thoc6

Reference Genes

BioGPS Gene:79227 Thoc6

ENSEMBL:ENSRNOG00000003497

ENSEMBL:ENSRNOG00000003497.5 Thoc6

ENSEMBL:ENSRNOG00055026587

ENSEMBL:ENSRNOG00060007876

ENSEMBL:ENSRNOG00065009749

KEGG Gene (Rattus norvegicus):79227 Thoc6

Monarch:79227 Thoc6

NCBI Gene:79227 Thoc6

UCSC:Q6AY87 Thoc6

Reference Transcript

RefSeq:NM_024384.2 Thoc6

Other Identifiers

10740853

1369946_at

1371785_at

17654132

5670445

5672066

5727668

5848157

5874911

5908072

5995864

6034194

6121035

6223225

6306849

6328044

6366610

6404128

6441197

6493440

6740343

6745105

79227

A_44_P1038028

GE1161423

GE1239246

GE16012

GO:0005515

ILMN_1373609

PH_rn_0007145

rc_AA957270_at

rc_AI137676_at

Participates

as a component of

THO complex [nucleoplasm] (Rattus norvegicus)

Inferred From

THOC6 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_077360.2

Ensembl

ENSRNOG00000003497, ENSRNOP00000004672, ENSRNOT00000004672

PRO

Q6AY87

RGD

708553