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Ptpn11 [nucleoplasm]
Stable Identifier
R-RNO-8937745
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
nucleoplasm
Synonyms
PTPN11, P41499
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional regulation by RUNX1 (Rattus norvegicus)
Regulation of RUNX1 Expression and Activity (Rattus norvegicus)
PTPN11 binds p-7Y-RUNX1 (Rattus norvegicus)
Ptpn11 [nucleoplasm] (Rattus norvegicus)
p-7Y-RUNX1:PTPN11 [nucleoplasm] (Rattus norvegicus)
Ptpn11 [nucleoplasm] (Rattus norvegicus)
PTPN11 dephosphorylates RUNX1 (Rattus norvegicus)
Ptpn11 [nucleoplasm] (Rattus norvegicus)
p-7Y-RUNX1:PTPN11 [nucleoplasm] (Rattus norvegicus)
Ptpn11 [nucleoplasm] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P41499 Ptpn11
Gene Names
Ptpn11
Chain
initiator methionine:1, chain:2-593
Reference Genes
BioGPS Gene:25622 Ptpn11
ENSEMBL:ENSRNOG00000030124 Ptpn11
KEGG Gene (Rattus norvegicus):25622 Ptpn11
Monarch:25622 Ptpn11
NCBI Gene:25622 Ptpn11
UCSC:P41499 Ptpn11
Reference Transcript
RefSeq:NM_001177593.1 Ptpn11
RefSeq:NM_013088.2 Ptpn11
Other Identifiers
10758727
10758744
1387668_at
1388379_at
17674151
25622
5701569
5784226
5806801
5838255
6066835
6247187
6254347
6265817
6295831
6326168
6356624
6379183
6398706
6659055
6684848
6693000
6726454
A_44_P317773
A_44_P460973
A_44_P999869
A_64_P004151
GE1283135
GE14369
GO:0000003
GO:0000077
GO:0000278
GO:0000902
GO:0001784
GO:0002376
GO:0003674
GO:0004721
GO:0004725
GO:0004726
GO:0005158
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005737
GO:0005739
GO:0005829
GO:0005886
GO:0006464
GO:0006470
GO:0006629
GO:0006641
GO:0006810
GO:0006913
GO:0006950
GO:0007049
GO:0007155
GO:0007165
GO:0007173
GO:0007229
GO:0007267
GO:0007409
GO:0007420
GO:0007507
GO:0008150
GO:0008283
GO:0008543
GO:0009755
GO:0009967
GO:0015031
GO:0016311
GO:0016787
GO:0016791
GO:0019899
GO:0019901
GO:0019904
GO:0021697
GO:0022607
GO:0030154
GO:0030159
GO:0030220
GO:0030674
GO:0030971
GO:0031748
GO:0032331
GO:0032528
GO:0032728
GO:0032755
GO:0032760
GO:0032991
GO:0033277
GO:0033628
GO:0033629
GO:0034330
GO:0035264
GO:0035265
GO:0035335
GO:0035855
GO:0036302
GO:0038127
GO:0040007
GO:0040011
GO:0042445
GO:0042592
GO:0042593
GO:0043226
GO:0043254
GO:0043274
GO:0043408
GO:0043560
GO:0044853
GO:0045296
GO:0045778
GO:0045931
GO:0046326
GO:0046628
GO:0046676
GO:0046825
GO:0046887
GO:0046888
GO:0048008
GO:0048011
GO:0048013
GO:0048609
GO:0048646
GO:0048659
GO:0048806
GO:0048839
GO:0048856
GO:0048870
GO:0048873
GO:0050731
GO:0050839
GO:0051428
GO:0051463
GO:0051894
GO:0055085
GO:0060020
GO:0060125
GO:0060325
GO:0061582
GO:0065003
GO:0070301
GO:0070374
GO:0071260
GO:0071364
GO:1904385
GO:1990314
GO:1990782
ILMN_1363069
PH_rn_0006733
PH_rn_0019279
U09307_at
U57499_g_at
rc_AI012725_s_at
rc_AI172465_at
Participates
as an output of
PTPN11 dephosphorylates RUNX1 (Rattus norvegicus)
as an input of
PTPN11 binds p-7Y-RUNX1 (Rattus norvegicus)
as a component of
p-7Y-RUNX1:PTPN11 [nucleoplasm] (Rattus norvegicus)
Other forms of this molecule
p-Y-Shp2 [cytosol]
Ptpn11 [cytosol]
phospho-Ptpn11 [cytosol]
Inferred From
PTPN11 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001171064.1
,
NP_037220.2
Ensembl
ENSRNOG00000030124
,
ENSRNOP00000041842
,
ENSRNOT00000046323
PRO
P41499
RGD
3447
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P09619 PDGFRB
3
p-11Y-PDGFRB [plasma membrane]
(R-HSA-8864039)
PDGFRB [plasma membrane]
(R-HSA-186767)
p-12Y-PDGFRB [plasma membrane]
(R-HSA-186803)
0.59
4
UniProt:P97710 Sirpa
9
pSirpa_Rat [plasma membrane]
(R-RNO-548918)
Sirpa_Rat [plasma membrane]
(R-RNO-548921)
phospho-Sirpa [plasma membrane]
(R-RNO-391102)
Sirpa [plasma membrane]
(R-RNO-197571-6)
Sirpa [tertiary granule membrane]
(R-RNO-6803288)
Sirpa [plasma membrane]
(R-RNO-3209922)
Sirpa [ficolin-1-rich granule membrane]
(R-RNO-6803321)
Sirpa [plasma membrane]
(R-RNO-197568-6)
Sirpa [secretory granule membrane]
(R-RNO-6804801-6)
0.544
3
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