p-Y-Yap1 translocates to the nucleus

Stable Identifier
R-RNO-8937920
Type
Reaction [transition]
Species
Rattus norvegicus
Compartment
General
SVG |   | PPTX  | SBGN
p-Y-Yap1 translocates to the nucleus

In rat osteosarcoma cells, Yap1, phosphorylated on an unknown tyrosine residue by activated Src and/or Yes1, translocates to the nucleus. Tyrosine phosphorylation does not change the ratio of nuclear and cytosolic Yap1 (Zaidi et al. 2004).

Literature References
PubMed ID Title Journal Year
14765127 Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription

Zaidi, SK, Sullivan, AJ, Medina, R, Ito, Y, van Wijnen, AJ, Stein, JL, Lian, JB, Stein, GS

EMBO J. 2004
Participants
Orthologous Events
Authored
Reviewed
Created