Reactome | RHOA:GDP [plasma membrane]

RHOA:GDP [plasma membrane]

Stable Identifier

R-RNO-8964174

Type

Complex

Species

Rattus norvegicus

Compartment

plasma membrane

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

GDP [cytosol]
RHOA [plasma membrane] (Rattus norvegicus)

Participates

as an output of

RHOA GAPs stimulate RHOA GTPase activity (Rattus norvegicus)
MYO9B inactivates RHOA (Rattus norvegicus)
Inactivation of Rho-GTP by p190RhoGAP (Rattus norvegicus)
ARHGAP35 stimulates RHOA GTPase activity (Rattus norvegicus)
The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA (Rattus norvegicus)

as an input of

GDIs block activation of RHOA (Rattus norvegicus)
RHOA GEFs activate RHOA (Rattus norvegicus)
p115-RhoGEF activation of RHOA (Rattus norvegicus)
NGEF exchanges GTP for GDP on RHOA (Rattus norvegicus)
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Rattus norvegicus)
RhoA is activated by nucleotide exchange and inhibits axonal growth (Rattus norvegicus)

as a component of

RHOA:GDP:ARHGDIA [plasma membrane] (Rattus norvegicus)

Inferred From

RHOA:GDP [plasma membrane] (Homo sapiens)