Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Activated Ntrk2 phosphorylates Shc1
Stable Identifier
R-RNO-9030485
Type
Reaction [transition]
Species
Rattus norvegicus
Compartment
plasma membrane
,
cytosol
ReviewStatus
5/5
General
SBML
|
BioPAX
Level 2
Level 3
|
PDF
SVG
|
PNG
Low
Medium
High
|
PPTX
|
SBGN
Rat Ntrk2, presumably activated by Bdnf or Ntf4 (Nt-4), phosphorylates Shc1 p52 isoform at tyrosine residue Y314 (corresponds to Y317 of human SHC1 p52 isoform) (Chan et al. 2011).
Literature References
PubMed ID
Title
Journal
Year
21615729
Amelioration of central cardiovascular regulatory dysfunction by tropomyocin receptor kinase B in a mevinphos intoxication model of brain stem death
Chen, WL
,
Li, FC
,
Hsu, KS
,
Chan, JY
,
Sun, EY
,
Chang, AY
,
Chan, SH
Br. J. Pharmacol.
2011
Participants
Input
ATP [cytosol]
Bdnf,Ntf4:p-5-Ntrk2:Shc1 [plasma membrane]
(Rattus norvegicus)
Output
ADP [cytosol]
Bdnf,Ntf4:p-5Y-Ntrk2 homodimer:p-Y314-Shc1 [plasma membrane]
(Rattus norvegicus)
Orthologous Events
NTRK2 phosphorylates SHC1 (Homo sapiens)
Authored
Orlic-Milacic, M (2018-01-05)
Reviewed
Castrén, E (2018-02-13)
Antila, H (2018-02-13)
Created
Orlic-Milacic, M (2017-11-28)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
