Formation of tri-heterotetramers of GluN1 (Grin1), GluN2A (Grin2a) and GluN3A (Grin3a)

Stable Identifier
R-RNO-9610275
Type
Reaction [binding]
Species
Rattus norvegicus
Compartment
endoplasmic reticulum membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Formation of tri-heterotetramers of GluN1 (Grin1), GluN2A (Grin2a) and GluN3A (Grin3a)
Recombinant rat GluN1 (Grin1) binds to GluN2A (Grin2a) and GluN3A (Grin3a) to form a tri-heteromeric NMDA receptor (Perez-Otano et al. 2001).
Literature References
PubMed ID Title Journal Year
11160393 Assembly with the NR1 subunit is required for surface expression of NR3A-containing NMDA receptors

Sucher, NJ, Lipton, SA, Heinemann, SF, Contractor, A, Perez-Otano, I, Trimmer, JS, Schulteis, CT

J. Neurosci. 2001
Participants
Input
Output
Orthologous Events
Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2A (GRIN2A) and GluN3A (GRIN3A) (Homo sapiens)
Authored
Orlic-Milacic, M  (2019-01-05)
Reviewed
Traynelis, SF  (2019-02-11)
Camp, C  (2019-02-11)
Bhattacharya, S  (2019-02-11)
Created
Orlic-Milacic, M  (2018-06-06)
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