Ppm1f dephosphorylates p-T286-CaMKII-alpha

Stable Identifier
R-RNO-9619459
Type
Reaction [transition]
Species
Rattus norvegicus
Compartment
cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Ppm1f dephosphorylates p-T286-CaMKII-alpha
Recombinant rat Protein phosphatase 1F (Ppm1f, also known as CaM-kinase phosphatase or CaMKPase) dephosphorylates autophosphorylation site, threonine 286 (T286), of recombinant rat CaMKII-alpha (CAMK2A) fragment. Recombinant rat Ppm1f is also active in dephosphorylating autophosphorylated CaMKII isolated from the rat brain (Ishida et al. 1998).
Literature References
PubMed ID Title Journal Year
9442023 A novel protein phosphatase that dephosphorylates and regulates Ca2+/calmodulin-dependent protein kinase II

Ishida, A, Fujisawa, H, Kameshita, I

J. Biol. Chem. 1998
Participants
Input
Output
Catalyst Activity

protein serine/threonine phosphatase activity of Ppm1f [cytosol]

Physical Entity
Ppm1f [cytosol] (Rattus norvegicus)
Activity
protein serine/threonine phosphatase activity (GO:0004722)
Orthologous Events
PPM1F dephosphorylates p-T286-CaMKII (Homo sapiens)
Authored
Orlic-Milacic, M  (2018-10-10)
Reviewed
Hansen, KB  (2018-11-02)
Yi, F  (2018-11-02)
Created
Orlic-Milacic, M  (2018-09-17)
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