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Prkab1 [cytosol]
Stable Identifier
R-RNO-9619496
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
5'-AMP-activated protein kinase subunit beta-1, AAKB1_RAT
Locations in the PathwayBrowser
Expand all
Autophagy (Rattus norvegicus)
Macroautophagy (Rattus norvegicus)
AMPK (complex) phosphorylates ULK1 (complex) (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
Thr-180 of ULK1 is phosphorylated (Rattus norvegicus)
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
ULK complex translocates to the ER (Rattus norvegicus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
ULK1 phosphorylates AMBRA1:BECN1 complex (Rattus norvegicus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
ULK1 phosphorylates ATG13 and RB1CC1 (Rattus norvegicus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
ULK1 phosphorylates Beclin-1 (Rattus norvegicus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
p-AMPK:AMP binds the ULK complex (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
Gene expression (Transcription) (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional Regulation by TP53 (Rattus norvegicus)
TP53 Regulates Metabolic Genes (Rattus norvegicus)
SESN1,2,3 bind AMPK (Rattus norvegicus)
SESN1,2,3:p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
p-AMPK phosphorylates TSC1:TSC2 (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
MTOR signalling (Rattus norvegicus)
Energy dependent regulation of mTOR by LKB1-AMPK (Rattus norvegicus)
AMPK is dephosphorylated (Rattus norvegicus)
AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
AMPK phosphorylates Raptor in the mTORC1 complex (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
Activation of cytosolic AMPK by phosphorylation (Rattus norvegicus)
AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
Phosphorylated AMPK binds AMP (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
p-AMPK phosphorylates TSC1:TSC2 (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer [cytosol] (Rattus norvegicus)
AMPK beta [cytosol] (Rattus norvegicus)
Prkab1 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P80386 Prkab1
Gene Names
Prkab1
Chain
initiator methionine:, chain:2-270
Reference Genes
BioGPS Gene:83803 Prkab1
ENSEMBL:ENSRNOG00000001142 Prkab1
KEGG Gene (Rattus norvegicus):83803 Prkab1
Monarch:83803 Prkab1
NCBI Gene:83803 Prkab1
UCSC:P80386 Prkab1
Reference Transcript
RefSeq:NM_031976.1 Prkab1
RefSeq:XM_006249481.3 Prkab1
Other Identifiers
10758940
1386945_a_at
17674397
6025113
6041588
6203234
6240472
6428678
6544397
6589740
6648226
6707188
83803
A_44_P1056161
GE22211
GO:0003824
GO:0004672
GO:0005515
GO:0005634
GO:0006468
GO:0010628
GO:0016740
GO:0031588
GO:0031669
GO:0035878
GO:0036211
GO:0043226
GO:0048856
GO:0120162
GO:0140096
PH_rn_0004776
X95577_at
Participates
as a component of
p-T183-AMPKalpha1beta1gamma1 [cytosol] (Rattus norvegicus)
AMPKalpha1beta1gamma1 [cytosol] (Rattus norvegicus)
as a member of
AMPK beta [cytosol] (Rattus norvegicus)
Other forms of this molecule
Prkab1 [nucleoplasm]
Inferred From
PRKAB1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_006249543.1
,
NP_114182.1
Ensembl
ENSRNOP00000001508
,
ENSRNOG00000001142
,
ENSRNOT00000001508
PRO
P80386
RGD
71057
PDB
5UFU
,
5KQ5
,
4QFR
,
6E4T
,
4YEF
,
4QFG
,
1Z0N
,
4EAL
,
4QFS
,
4EAK
,
6E4U
,
5T5T
,
6E4W
,
1Z0M
,
4EAG
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O18645
7
PRKAA2 [nucleoplasm]
(R-DME-163682)
phospho-p-T172-PRKAA2 [nucleoplasm]
(R-DME-164171)
phospho-p-T183-PRKAA1 [nucleoplasm]
(R-DME-2151206)
PRKAA1 [cytosol]
(R-DME-380935)
phospho-p-T183-PRKAA1 [cytosol]
(R-DME-380964)
phospho-p-T172-PRKAA2 [cytosol]
(R-DME-200417)
PRKAA2 [cytosol]
(R-DME-200405)
0.591
3
UniProt:G3V7Q7
3
Iqgap1 [plasma membrane]
(R-RNO-381681)
Iqgap1 [secretory granule membrane]
(R-RNO-6804803)
Iqgap1 [cytosol]
(R-RNO-5626371)
0.499
2
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