Reactome | Asb9 [cytosol]

Asb9 [cytosol]

Stable Identifier

R-RNO-975424

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

ASB9, F1M6U5

Locations in the PathwayBrowser

Expand all

Immune System (Rattus norvegicus)

- Adaptive Immune System (Rattus norvegicus)
  - Class I MHC mediated antigen processing & presentation (Rattus norvegicus)
    - Antigen processing: Ubiquitination & Proteasome degradation (Rattus norvegicus)
      - Interaction of E3 with substrate and E2-Ub complex (Rattus norvegicus)
        
        Ag-substrate:E3:E2:Ub [cytosol] (Rattus norvegicus)
        
        E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Rattus norvegicus)
        
        ASB family [cytosol] (Rattus norvegicus)
        
        Asb9 [cytosol] (Rattus norvegicus)
        
        E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Rattus norvegicus)
        
        ASB family [cytosol] (Rattus norvegicus)
        
        Asb9 [cytosol] (Rattus norvegicus)
      - Polyubiquitination of substrate (Rattus norvegicus)
        
        E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Rattus norvegicus)
        
        ASB family [cytosol] (Rattus norvegicus)
        
        Asb9 [cytosol] (Rattus norvegicus)
        
        E3:K48-polyubiquitinated substrate [cytosol] (Rattus norvegicus)
        
        E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Rattus norvegicus)
        
        ASB family [cytosol] (Rattus norvegicus)
        
        Asb9 [cytosol] (Rattus norvegicus)
        
        E3:Ub:substrate [cytosol] (Rattus norvegicus)
        
        E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Rattus norvegicus)
        
        ASB family [cytosol] (Rattus norvegicus)
        
        Asb9 [cytosol] (Rattus norvegicus)
      - Release of E3 from polyubiquitinated substrate (Rattus norvegicus)
        
        E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Rattus norvegicus)
        
        ASB family [cytosol] (Rattus norvegicus)
        
        Asb9 [cytosol] (Rattus norvegicus)
        
        E3:K48-polyubiquitinated substrate [cytosol] (Rattus norvegicus)
        
        E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Rattus norvegicus)
        
        ASB family [cytosol] (Rattus norvegicus)
        
        Asb9 [cytosol] (Rattus norvegicus)
      - Transfer of Ub from E2 to substrate and release of E2 (Rattus norvegicus)
        
        Ag-substrate:E3:E2:Ub [cytosol] (Rattus norvegicus)
        
        E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Rattus norvegicus)
        
        ASB family [cytosol] (Rattus norvegicus)
        
        Asb9 [cytosol] (Rattus norvegicus)
        
        E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Rattus norvegicus)
        
        ASB family [cytosol] (Rattus norvegicus)
        
        Asb9 [cytosol] (Rattus norvegicus)
        
        E3:Ub:substrate [cytosol] (Rattus norvegicus)
        
        E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Rattus norvegicus)
        
        ASB family [cytosol] (Rattus norvegicus)
        
        Asb9 [cytosol] (Rattus norvegicus)

Metabolism of proteins (Rattus norvegicus)

- Post-translational protein modification (Rattus norvegicus)
  - Neddylation (Rattus norvegicus)
    - AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex (Rattus norvegicus)
      - NEDD8-AcM-UBE2F:CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
        
        CUL5-box protein [cytosol] (Rattus norvegicus)
        
        Asb9 [cytosol] (Rattus norvegicus)
      - NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
        
        NEDD8-CRL5 E3 ligase [cytosol] (Rattus norvegicus)
        
        CUL5-box protein [cytosol] (Rattus norvegicus)
        
        Asb9 [cytosol] (Rattus norvegicus)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Rattus norvegicus)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Rattus norvegicus)
        
        CRL E3 ubiquitin ligases [cytosol] (Rattus norvegicus)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
        
        CUL5-box protein [cytosol] (Rattus norvegicus)
        
        Asb9 [cytosol] (Rattus norvegicus)
      - CRL E3 ubiquitin ligases [cytosol] (Rattus norvegicus)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
        
        CUL5-box protein [cytosol] (Rattus norvegicus)
        
        Asb9 [cytosol] (Rattus norvegicus)
    - COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Rattus norvegicus)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Rattus norvegicus)
        
        CRL E3 ubiquitin ligases [cytosol] (Rattus norvegicus)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
        
        CUL5-box protein [cytosol] (Rattus norvegicus)
        
        Asb9 [cytosol] (Rattus norvegicus)
      - CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
        
        CUL5-box protein [cytosol] (Rattus norvegicus)
        
        Asb9 [cytosol] (Rattus norvegicus)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Rattus norvegicus)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
        
        CUL5-box protein [cytosol] (Rattus norvegicus)
        
        Asb9 [cytosol] (Rattus norvegicus)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
        
        NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
        
        NEDD8-CRL5 E3 ligase [cytosol] (Rattus norvegicus)
        
        CUL5-box protein [cytosol] (Rattus norvegicus)
        
        Asb9 [cytosol] (Rattus norvegicus)
    - NEDD8:AcM-UBE2F binds CRL5 E3 ubiquitin ligase complex (Rattus norvegicus)
      - CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
        
        CUL5-box protein [cytosol] (Rattus norvegicus)
        
        Asb9 [cytosol] (Rattus norvegicus)
      - NEDD8-AcM-UBE2F:CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
        
        CUL5-box protein [cytosol] (Rattus norvegicus)
        
        Asb9 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:F1M6U5

Gene Names

Asb9

Reference Genes

BioGPS Gene:367785 Asb9

ENSEMBL:ENSRNOG00000003452

ENSEMBL:ENSRNOG00000067365

ENSEMBL:ENSRNOG00000067365.1 Asb9

KEGG Gene (Rattus norvegicus):367785 Asb9

Monarch:367785 Asb9

NCBI Gene:367785 Asb9

Reference Transcript

Other Identifiers

10937703

1384283_at

17876984

367785

5660121

5941413

6076031

6146195

6294398

6396566

6434912

6435027

6695258

A_44_P140429

GE1220216

GO:0005515

GO:0016567

GO:0023052

GO:0030163

GO:0035556

GO:0036211

GO:0045732

ILMN_1356583

PH_rn_0017222

rc_AA893314_at

Participates

as a member of

Inferred From

ASB9 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_017457609.1, XP_006256945.1, NP_001178842.1

Ensembl

ENSRNOT00000041515, ENSRNOG00000067365, ENSRNOP00000038983

RGD

1560537

Cite Us!