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Skp2 [nucleoplasm]
Stable Identifier
R-RNO-975554
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
nucleoplasm
Synonyms
SKP2, A0A8I6AMP0
Locations in the PathwayBrowser
Expand all
Cell Cycle (Rattus norvegicus)
Cell Cycle, Mitotic (Rattus norvegicus)
Mitotic G1 phase and G1/S transition (Rattus norvegicus)
G1 Phase (Rattus norvegicus)
Cyclin D associated events in G1 (Rattus norvegicus)
Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex (Rattus norvegicus)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
p-T401,S672,1035-RBL2:SCF(Skp2):Cks1 [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
Ubiquitination of p130 (RBL2) by SCF (Skp2) (Rattus norvegicus)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
p-T401,S672,1035-RBL2:SCF(Skp2):Cks1 [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
G1/S Transition (Rattus norvegicus)
Cyclin E associated events during G1/S transition (Rattus norvegicus)
SCF(Skp2)-mediated degradation of p27/p21 (Rattus norvegicus)
Association of Cks1 with SCF(Skp2) complex (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Rattus norvegicus)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Rattus norvegicus)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Rattus norvegicus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
Ubiquitination of phospho-p27/p21 (Rattus norvegicus)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Rattus norvegicus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
Regulation of mitotic cell cycle (Rattus norvegicus)
APC/C-mediated degradation of cell cycle proteins (Rattus norvegicus)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Rattus norvegicus)
APC/C:Cdh1 polyubiquitinates SKP2 (Rattus norvegicus)
RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
RB1 recruits APC/C:Cdh1 complex to SKP2 (Rattus norvegicus)
RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
S Phase (Rattus norvegicus)
Cyclin A:Cdk2-associated events at S phase entry (Rattus norvegicus)
SCF(Skp2)-mediated degradation of p27/p21 (Rattus norvegicus)
Association of Cks1 with SCF(Skp2) complex (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Rattus norvegicus)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Rattus norvegicus)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Rattus norvegicus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
Ubiquitination of phospho-p27/p21 (Rattus norvegicus)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Rattus norvegicus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
Synthesis of DNA (Rattus norvegicus)
Switching of origins to a post-replicative state (Rattus norvegicus)
Orc1 removal from chromatin (Rattus norvegicus)
Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Rattus norvegicus)
SCF (SKP2) complex [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
DNA Replication (Rattus norvegicus)
Synthesis of DNA (Rattus norvegicus)
Switching of origins to a post-replicative state (Rattus norvegicus)
Orc1 removal from chromatin (Rattus norvegicus)
Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Rattus norvegicus)
SCF (SKP2) complex [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Deubiquitination (Rattus norvegicus)
Ub-specific processing proteases (Rattus norvegicus)
USP13 binds UFD1L:SKP2 (Rattus norvegicus)
UFD1L:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
USP13:UFD1L:SKP2 [nucleoplasm] (Rattus norvegicus)
UFD1L:SKP2 [nucleoplasm] (Rattus norvegicus)
Skp2 [nucleoplasm] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:A0A8I6AMP0
Gene Names
Skp2
Reference Genes
ENSEMBL:ENSRNOG00000059059
UCSC:A0A8I6AMP0 Skp2
Other Identifiers
10821840
1390823_at
17745766
294790
5631558
5696745
5707461
5731805
5776533
5965851
6034619
6067935
6162419
6194430
6225119
6314610
6442283
6473741
6591207
GE1109565
GO:0005515
ILMN_1371149
PH_rn_0012024
rc_AA924839_at
Participates
as a component of
UFD1L:SKP2 [nucleoplasm] (Rattus norvegicus)
SCF (SKP2) complex [nucleoplasm] (Rattus norvegicus)
RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm] (Rattus norvegicus)
as an input of
RB1 recruits APC/C:Cdh1 complex to SKP2 (Rattus norvegicus)
Other forms of this molecule
Skp2 [cytosol]
Skp2 [nucleoplasm]
Inferred From
SKP2 [nucleoplasm]
(Homo sapiens)
Cross References
ENSEMBL
ENSRNOT00000115243
,
ENSRNOP00000095009
,
ENSRNOG00000059059
RGD
1562456
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