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ALKAL2:(ALKAL1) [extracellular region]
Stable Identifier
R-RNO-9842597
Type
Set [CandidateSet]
Species
Rattus norvegicus
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by ALK (Rattus norvegicus)
ALK autophosphorylation (Rattus norvegicus)
ALK dimer:ligand:type I ALK binding TKI [plasma membrane] (Rattus norvegicus)
ligand-bound ALK dimer [plasma membrane] (Rattus norvegicus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
ligand-bound ALK dimer [plasma membrane] (Rattus norvegicus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
ALK binds ALKAL ligand (Rattus norvegicus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Active ALK binds JAK3 (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Active ALK:JAK3 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Active ALK binds PLCG1 (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Active ALK:PLCG1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Active ALK binds SHC1 (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Active ALK:SHC1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Active ALK dimer binds IRS1 (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Active ALK:IRS1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Active ALK phosphorylates IRS1 (Rattus norvegicus)
Active ALK:IRS1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Active ALK:pY-IRS1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Active ALK phosphorylates JAK3 (Rattus norvegicus)
Active ALK:JAK3 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Active ALK:p-Y980 JAK3 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Active ALK phosphorylates PLCG1 (Rattus norvegicus)
Active ALK:PLCG1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Active ALK:p-4Y PLCG1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Active ALK phosphorylates SHC1 (Rattus norvegicus)
Active ALK:SHC1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Active ALK:p-3Y SHC1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Active ALK recruits PI3K (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Active ALK:PI3K [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Liganded-ALK dimer binds type I ALK-binding TKIs (Rattus norvegicus)
ALK dimer:ligand:type I ALK binding TKI [plasma membrane] (Rattus norvegicus)
ligand-bound ALK dimer [plasma membrane] (Rattus norvegicus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
ligand-bound ALK dimer [plasma membrane] (Rattus norvegicus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
PI3K synthesizes PIP3 downstream of ALK (Rattus norvegicus)
Active ALK:PI3K [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
PTPN6 dephosphorylates JAK3 (Rattus norvegicus)
Active ALK:JAK3 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Active ALK:p-Y980 JAK3 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
STAT3 is phosphorylated downstream of active ALK (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALKAL2:(ALKAL1) [extracellular region] (Rattus norvegicus)
Participants
members
ALKAL2 dimer [extracellular region]
(Rattus norvegicus)
candidates
Alkal1 [extracellular region]
(Rattus norvegicus)
Participates
as a component of
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
as an input of
ALK binds ALKAL ligand (Rattus norvegicus)
Inferred From
ALKAL2:(ALKAL1) [extracellular region]
(Homo sapiens)
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