Reactome | N [viral capsid]

N [viral capsid]

Stable Identifier

R-RSY-9823364

Type

Protein [EntityWithAccessionedSequence]

Species

Human respiratory syncytial virus A

Compartment

viral capsid

Synonyms

Nucleoprotein, Nucleocapsid protein, Protein N

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Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - Respiratory Syncytial Virus Infection Pathway (Homo sapiens)
      - Assembly and release of respiratory syncytial virus (RSV) virions (Homo sapiens)
        
        Budding of hRSV A virions from infected cell (Homo sapiens)
        
        Replicated hRSV A virion [extracellular region] (Human respiratory syncytial virus A)
        
        Matrix lattice-enclosed hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid:Packaged RdRP:p-M2-1 [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N decamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N hendecamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
      - RSV-host interactions (Homo sapiens)
        
        G protein binds CX3CR1 on host cell surface (Homo sapiens)
        
        hRSV A virion:CX3CR1 [plasma membrane] (Homo sapiens)
        
        hRSV A virion [extracellular region] (Human respiratory syncytial virus A)
        
        Matrix lattice-enclosed hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid:Packaged RdRP:p-M2-1 [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N decamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N hendecamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A virion [extracellular region] (Human respiratory syncytial virus A)
        
        Matrix lattice-enclosed hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid:Packaged RdRP:p-M2-1 [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N decamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N hendecamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        RSV F binds TLR4:LY96:CD14 (Homo sapiens)
        
        TLR4:LY96:CD14:RSV A virion [plasma membrane] (Homo sapiens)
        
        hRSV A virion [extracellular region] (Human respiratory syncytial virus A)
        
        Matrix lattice-enclosed hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid:Packaged RdRP:p-M2-1 [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N decamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N hendecamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A virion [extracellular region] (Human respiratory syncytial virus A)
        
        Matrix lattice-enclosed hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid:Packaged RdRP:p-M2-1 [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N decamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N hendecamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        RSV G binds CD209,CLEC4M (Homo sapiens)
        
        RSV virion:CD209,CLEC4M [plasma membrane] (Homo sapiens)
        
        hRSV A virion [extracellular region] (Human respiratory syncytial virus A)
        
        Matrix lattice-enclosed hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid:Packaged RdRP:p-M2-1 [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N decamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N hendecamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A virion [extracellular region] (Human respiratory syncytial virus A)
        
        Matrix lattice-enclosed hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid:Packaged RdRP:p-M2-1 [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N decamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N hendecamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
      - Respiratory syncytial virus (RSV) attachment and entry (Homo sapiens)
        
        F inhibitors bind F on RSV virion (Homo sapiens)
        
        F inhibitors:RSV virion [extracellular region] (Human respiratory syncytial virus A)
        
        hRSV A virion [extracellular region] (Human respiratory syncytial virus A)
        
        Matrix lattice-enclosed hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid:Packaged RdRP:p-M2-1 [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N decamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N hendecamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A virion [extracellular region] (Human respiratory syncytial virus A)
        
        Matrix lattice-enclosed hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid:Packaged RdRP:p-M2-1 [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N decamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N hendecamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        F protein binds NCL on host cell surface (Homo sapiens)
        
        hRSV A virion:CX3CR1 [plasma membrane] (Homo sapiens)
        
        hRSV A virion [extracellular region] (Human respiratory syncytial virus A)
        
        Matrix lattice-enclosed hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid:Packaged RdRP:p-M2-1 [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N decamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N hendecamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A virion:CX3CR1:NCL [plasma membrane] (Homo sapiens)
        
        hRSV A virion:CX3CR1 [plasma membrane] (Homo sapiens)
        
        hRSV A virion [extracellular region] (Human respiratory syncytial virus A)
        
        Matrix lattice-enclosed hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid:Packaged RdRP:p-M2-1 [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N decamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N hendecamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        G protein binds CX3CR1 on host cell surface (Homo sapiens)
        
        hRSV A virion:CX3CR1 [plasma membrane] (Homo sapiens)
        
        hRSV A virion [extracellular region] (Human respiratory syncytial virus A)
        
        Matrix lattice-enclosed hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid:Packaged RdRP:p-M2-1 [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N decamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N hendecamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A virion [extracellular region] (Human respiratory syncytial virus A)
        
        Matrix lattice-enclosed hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid:Packaged RdRP:p-M2-1 [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N decamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N hendecamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        RSV F binds TLR4:LY96:CD14 (Homo sapiens)
        
        TLR4:LY96:CD14:RSV A virion [plasma membrane] (Homo sapiens)
        
        hRSV A virion [extracellular region] (Human respiratory syncytial virus A)
        
        Matrix lattice-enclosed hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid:Packaged RdRP:p-M2-1 [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N decamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N hendecamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A virion [extracellular region] (Human respiratory syncytial virus A)
        
        Matrix lattice-enclosed hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid:Packaged RdRP:p-M2-1 [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N decamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N hendecamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        Release of hRSV A nucleocapsid from macropinosome (Homo sapiens)
        
        hRSV A virion:CX3CR1:NCL [macropinosome membrane] (Homo sapiens)
        
        hRSV A virion:CX3CR1 [macropinosome membrane] (Homo sapiens)
        
        hRSV A virion [macropinosome membrane] (Human respiratory syncytial virus A)
        
        Matrix lattice-enclosed hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid:Packaged RdRP:p-M2-1 [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N decamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N hendecamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A enters host cell through macropinocytosis (Homo sapiens)
        
        hRSV A virion:CX3CR1:NCL [macropinosome membrane] (Homo sapiens)
        
        hRSV A virion:CX3CR1 [macropinosome membrane] (Homo sapiens)
        
        hRSV A virion [macropinosome membrane] (Human respiratory syncytial virus A)
        
        Matrix lattice-enclosed hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid:Packaged RdRP:p-M2-1 [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N decamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N hendecamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A virion:CX3CR1:NCL [plasma membrane] (Homo sapiens)
        
        hRSV A virion:CX3CR1 [plasma membrane] (Homo sapiens)
        
        hRSV A virion [extracellular region] (Human respiratory syncytial virus A)
        
        Matrix lattice-enclosed hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid:Packaged RdRP:p-M2-1 [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N decamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N hendecamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A enters host cell through membrane fusion (Homo sapiens)
        
        hRSV A virion:CX3CR1:NCL [plasma membrane] (Homo sapiens)
        
        hRSV A virion:CX3CR1 [plasma membrane] (Homo sapiens)
        
        hRSV A virion [extracellular region] (Human respiratory syncytial virus A)
        
        Matrix lattice-enclosed hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid:Packaged RdRP:p-M2-1 [viral capsid] (Human respiratory syncytial virus A)
        
        hRSV A nucleocapsid [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N decamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)
        
        Protein N hendecamer [viral capsid] (Human respiratory syncytial virus A)
        
        N [viral capsid] (Human respiratory syncytial virus A)

External Reference Information

External Reference

UniProt:P03418 N

Gene Names

Chain

chain:1-391

Reference Genes

UCSC:P03418 N

Participates

as a component of

Other forms of this molecule

p-N [viral capsid]

Nascent N [cytosol]

p-N [cytosol]

Cross References

PDB

4UC6, 2WJ8, 4UC7, 2YHM, 8OP2, 4UC8, 8OOU, 4UC9, 4UCA, 4UCC, 4UCD, 4UCE, 4UCB, 6YJL, 8OP1, 4BKK

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:hspa1a_hspa1b_human-1 EBI-11820565			0.576	3
UniProt:Q9BQA1 WDR77	3	WDR77 [cytosol] (R-HSA-191823) pT5-WDR77 [nucleoplasm] (R-HSA-5205602) WDR77 [nucleoplasm] (R-HSA-5205610)	0.576	3
UniProt:O14744 PRMT5	3	PRMT5 [cytosol] (R-HSA-191876) PRMT5 [nucleoplasm] (R-HSA-5205609) p-Y297,304,307-PRMT5 [nucleoplasm] (R-HSA-5211300)	0.499	2
UniProt:P03421 P	3	p-S232,S237-P [cytosol] (R-RSY-9832783) Nascent P [cytosol] (R-RSY-9831695) p-P [cytosol] (R-RSY-9825432)	0.491	2

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