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phospho-p-S317,S345-CHEK1 [nucleoplasm]
Stable Identifier
R-SCE-113838
Type
Protein [EntityWithAccessionedSequence]
Species
Saccharomyces cerevisiae
Compartment
nucleoplasm
Synonyms
P38691
Locations in the PathwayBrowser
Expand all
Cell Cycle (Saccharomyces cerevisiae)
Cell Cycle Checkpoints (Saccharomyces cerevisiae)
G1/S DNA Damage Checkpoints (Saccharomyces cerevisiae)
p53-Independent G1/S DNA damage checkpoint (Saccharomyces cerevisiae)
p53-Independent DNA Damage Response (Saccharomyces cerevisiae)
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A (Saccharomyces cerevisiae)
Phosphorylation of Cdc25A at Ser-123 by Chk1 (Saccharomyces cerevisiae)
phospho-p-S317,S345-CHEK1 [nucleoplasm] (Saccharomyces cerevisiae)
G2/M Checkpoints (Saccharomyces cerevisiae)
Activation of ATR in response to replication stress (Saccharomyces cerevisiae)
Phosphorylation of Cdc25A at Ser-123 by Chk1 (Saccharomyces cerevisiae)
phospho-p-S317,S345-CHEK1 [nucleoplasm] (Saccharomyces cerevisiae)
Phosphorylation of Cdc25C at Ser 216 by Chk1 (Saccharomyces cerevisiae)
phospho-p-S317,S345-CHEK1 [nucleoplasm] (Saccharomyces cerevisiae)
DNA Repair (Saccharomyces cerevisiae)
DNA Double-Strand Break Repair (Saccharomyces cerevisiae)
Homology Directed Repair (Saccharomyces cerevisiae)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Saccharomyces cerevisiae)
HDR through Homologous Recombination (HRR) (Saccharomyces cerevisiae)
Homologous DNA Pairing and Strand Exchange (Saccharomyces cerevisiae)
Presynaptic phase of homologous DNA pairing and strand exchange (Saccharomyces cerevisiae)
CHEK1 phosphorylates RAD51 (Saccharomyces cerevisiae)
phospho-p-S317,S345-CHEK1 [nucleoplasm] (Saccharomyces cerevisiae)
External Reference Information
External Reference
UniProt:P38691
Reference Genes
BioGPS Gene:856482
ENSEMBL:YHR082C
KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YHR082C
Monarch:856482
NCBI Gene:856482
SGD:YHR082C
Reference Transcript
RefSeq:NM_001179212.1
Other Identifiers
1773969_at
4464_at
856482
GO:0000166
GO:0003674
GO:0003723
GO:0003729
GO:0004672
GO:0004674
GO:0004712
GO:0005515
GO:0005524
GO:0005575
GO:0005634
GO:0005737
GO:0006417
GO:0006468
GO:0007124
GO:0008104
GO:0008150
GO:0010494
GO:0010506
GO:0010570
GO:0016242
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0031929
GO:0034613
GO:0035556
GO:0043167
GO:0043555
GO:0106310
GO:2000220
Other forms of this molecule
CHEK1 [cytosol]
CHEK1 [nucleoplasm]
Inferred From
p-S317,S345-CHEK1 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 317 (in Homo sapiens)
Coordinate
317
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 345 (in Homo sapiens)
Coordinate
345
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_011950.1
PRO
P38691
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P38873
2
KOG1 [nucleoplasm]
(R-SCE-5083664)
KOG1 [cytosol]
(R-SCE-3006727)
0.69
4
UniProt:Q08921 TCO89
0.597
3
UniProt:P36005
4
CDK4 [cytosol]
(R-SCE-68330-2)
CDK6 [cytosol]
(R-SCE-68336-2)
CDK4 [nucleoplasm]
(R-SCE-113843-2)
CDK6 [nucleoplasm]
(R-SCE-141283-2)
0.527
2
UniProt:P53233 FMP48
0.527
3
UniProt:P29311 BMH1
1
BMH1 [cytosol]
(R-SCE-1454714)
0.527
2
UniProt:P35169 TOR1
0.499
2
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