Reactome | Erf-1 [cytosol]

Erf-1 [cytosol]

Stable Identifier

R-SCE-141665

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

Eukaryotic peptide chain release factor subunit 1

External Reference Information

External Reference

UniProt:P12385 SUP45

Gene Names

SUP45, SAL4, SUP1, YBR143C, YBR1120

Chain

chain:1-437

Reference Genes

BioGPS Gene:852440 SUP45

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YBR143C SUP45

Monarch:852440 SUP45

NCBI Gene:852440 SUP45

Reference Transcript

RefSeq:NM_001178491.3 SUP45

Other Identifiers

4932.YBR143C

4CRM

4CRN

CAA27719.1

CAA51935.1

CAA85101.1

DAA07259.1

EntrezGene:852440

EntrezGene:SUP45

GO:0003674

GO:0003723

GO:0003747

GO:0005575

GO:0005737

GO:0005829

GO:0006353

GO:0006415

GO:0008135

GO:0008150

GO:0010494

GO:0016149

GO:0018444

IPR004403

IPR005140

IPR005141

IPR005142

IPR024049

IPR029064

IPR042226

M28042

NM_001178491.3

NP_009701.3

PF03463

PF03464

PF03465

SM01194

UPI0000052FB8

YBR143C

YBR143C_mRNA

Participant Of

input

GTP bound eRF3:eRF1 complex binds the peptidyl-tRNA:mRNA:Ribosome complex

hasComponent

Other forms of this molecule

Me-Q185-ETF1 [cytosol]

ETF1 [cytosol]

Cross References

RefSeq

NP_009701.3

PRO

P12385

PDB

4CRN, 4CRM

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P05453 SUP35	3	GSPT1 [cytosol] (R-SCE-8865759) eRF3 [cytosol] (R-SCE-141686) GSPT2 [cytosol] (R-SCE-143379)	0.846	37
UniProt:Q03195	1	ABCE1 [cytosol] (R-SCE-8985209)	0.616	5
UniProt:P10591	23	HSPA8 [nucleoplasm] (R-SCE-5082380-2) HSPA8 [cytosol] (R-SCE-264476-2) HSPA6 [ficolin-1-rich granule lumen] (R-SCE-6801512-2) HSPA1A [ficolin-1-rich granule lumen] (R-SCE-6801496-2) HSPA8 [ficolin-1-rich granule lumen] (R-SCE-6801494-2) HSPA1A [extracellular region] (R-SCE-6805872-2) HSPA6 [extracellular region] (R-SCE-6806500-2) HSPA8 [extracellular region] (R-SCE-6805936-2) HSPA8 [secretory granule lumen] (R-SCE-6801530-2) HSPA6 [secretory granule lumen] (R-SCE-6801472-2) HSPA2 [nucleoplasm] (R-SCE-912480-2) HSPA1L [nucleoplasm] (R-SCE-5082367-2) HSPA1A [nucleoplasm] (R-SCE-6792605-2) HSPA6 [nucleoplasm] (R-SCE-5252088-2) HSPA13 [nucleoplasm] (R-SCE-5252009-2) HSPA7 [nucleoplasm] (R-SCE-5252047-2) HSPA1L [cytosol] (R-SCE-3371410-2) HSPA2 [cytosol] (R-SCE-3371408-2) HSPA13 [cytosol] (R-SCE-5251981-2) HSPA6 [cytosol] (R-SCE-3371521-2) HSPA7 [cytosol] (R-SCE-5251954-2) HSPA1A [cytosol] (R-SCE-6792602-2) Me3K561-HSPA8 [nucleoplasm] (R-SCE-8932217-2)	0.527	2
UniProt:P10592	23	HSPA8 [nucleoplasm] (R-SCE-5082380-3) HSPA8 [cytosol] (R-SCE-264476-3) HSPA6 [ficolin-1-rich granule lumen] (R-SCE-6801512-3) HSPA1A [ficolin-1-rich granule lumen] (R-SCE-6801496-3) HSPA8 [ficolin-1-rich granule lumen] (R-SCE-6801494-3) HSPA1A [extracellular region] (R-SCE-6805872-3) HSPA6 [extracellular region] (R-SCE-6806500-3) HSPA8 [extracellular region] (R-SCE-6805936-3) HSPA8 [secretory granule lumen] (R-SCE-6801530-3) HSPA6 [secretory granule lumen] (R-SCE-6801472-3) HSPA2 [nucleoplasm] (R-SCE-912480-3) HSPA1L [nucleoplasm] (R-SCE-5082367-3) HSPA1A [nucleoplasm] (R-SCE-6792605-3) HSPA6 [nucleoplasm] (R-SCE-5252088-3) HSPA13 [nucleoplasm] (R-SCE-5252009-3) HSPA7 [nucleoplasm] (R-SCE-5252047-3) HSPA1L [cytosol] (R-SCE-3371410-3) HSPA2 [cytosol] (R-SCE-3371408-3) HSPA13 [cytosol] (R-SCE-5251981-3) HSPA6 [cytosol] (R-SCE-3371521-3) HSPA7 [cytosol] (R-SCE-5251954-3) HSPA1A [cytosol] (R-SCE-6792602-3) Me3K561-HSPA8 [nucleoplasm] (R-SCE-8932217-3)	0.527	2
UniProt:Q01477	3	USP37 [nucleoplasm] (R-SCE-5697000) USP10 [nucleoplasm] (R-SCE-3222218) USP10 [cytosol] (R-SCE-6782974)	0.527	2