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PAK1 [cytosol]
Stable Identifier
R-SCE-162629
Type
Protein [EntityWithAccessionedSequence]
Species
Saccharomyces cerevisiae
Compartment
cytosol
Synonyms
Q03497
Locations in the PathwayBrowser for interactor UniProt:Q12163 NBP2
Expand all
Immune System (Saccharomyces cerevisiae)
Innate Immune System (Saccharomyces cerevisiae)
Fcgamma receptor (FCGR) dependent phagocytosis (Saccharomyces cerevisiae)
Regulation of actin dynamics for phagocytic cup formation (Saccharomyces cerevisiae)
Autophosphorylation of PAK1 (Saccharomyces cerevisiae)
PAK1 [cytosol] (Saccharomyces cerevisiae)
RAC1 and CDC42 activate PAK1 (Saccharomyces cerevisiae)
PAK1 [cytosol] (Saccharomyces cerevisiae)
Signal Transduction (Saccharomyces cerevisiae)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Saccharomyces cerevisiae)
Signaling by Rho GTPases (Saccharomyces cerevisiae)
RHO GTPase Effectors (Saccharomyces cerevisiae)
RHO GTPases activate PAKs (Saccharomyces cerevisiae)
RAC1 and CDC42 activate PAK1 (Saccharomyces cerevisiae)
PAK1 [cytosol] (Saccharomyces cerevisiae)
External Reference Information
External Reference
UniProt:Q03497
Reference Genes
BioGPS Gene:856382
ENSEMBL:YHL007C
KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YHL007C
Monarch:856382
NCBI Gene:856382
SGD:YHL007C
Reference Transcript
RefSeq:NM_001179087.1
Other Identifiers
1769331_at
4555_at
856382
GO:0000011
GO:0000122
GO:0000131
GO:0000166
GO:0000185
GO:0000278
GO:0000282
GO:0000747
GO:0000750
GO:0000910
GO:0001402
GO:0001403
GO:0003674
GO:0003723
GO:0003729
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005575
GO:0005634
GO:0005737
GO:0005886
GO:0006325
GO:0006338
GO:0006366
GO:0006468
GO:0006869
GO:0007010
GO:0007033
GO:0007049
GO:0007096
GO:0007114
GO:0007118
GO:0007121
GO:0007124
GO:0007232
GO:0007266
GO:0008150
GO:0008349
GO:0009408
GO:0010629
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0019236
GO:0023052
GO:0030036
GO:0030427
GO:0031098
GO:0034063
GO:0034605
GO:0035376
GO:0035556
GO:0042221
GO:0043065
GO:0043167
GO:0043332
GO:0043408
GO:0044025
GO:0048285
GO:0048308
GO:0048365
GO:0051726
GO:0070925
GO:0106310
GO:1990872
Participates
as an output of
RAC1 and CDC42 activate PAK1 (Saccharomyces cerevisiae)
as a component of
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Saccharomyces cerevisiae)
PAK1 dimer [cytosol] (Saccharomyces cerevisiae)
as a member of
PAK1,2,3 [cytosol] (Saccharomyces cerevisiae)
Other forms of this molecule
PAK7 [plasma membrane]
PAK5 [cytosol]
PAK4 [cytosol]
PAK6 [cytosol]
phospho-p-S154,T436-PAK3 [cytosol]
PAK3 [cytosol]
PAK2 [cytosol]
phospho-p-S144,T423-PAK1 [cytosol]
phospho-p-S141,T402-PAK2 [cytosol]
Inferred From
PAK1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_011856.1
PRO
Q03497
PDB
2RQW
,
2LCS
,
2KYM
Interactors (10)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P29366
4
BEM1 [cytosol]
(R-SCE-8941242)
phospho-BEM1 [cytosol]
(R-SCE-9626854)
phospho-BEM1 [cytosol]
(R-SCE-9626824)
BEM1 [cytosol]
(R-SCE-1222707)
0.865
12
UniProt:P19073
10
RHOV [plasma membrane]
(R-SCE-194869)
RHOJ [plasma membrane]
(R-SCE-3006725)
phospho-p-Y254-RHOU [endosome membrane]
(R-SCE-9726860)
phospho-p-Y254-RHOU [plasma membrane]
(R-SCE-9726857)
RHOU [plasma membrane]
(R-SCE-194914)
RHOQ [plasma membrane]
(R-SCE-194879)
RHOQ [Golgi-associated vesicle membrane]
(R-SCE-5627086)
CDC42 [endoplasmic reticulum membrane]
(R-SCE-5672086)
CDC42 [plasma membrane]
(R-SCE-449545)
CDC42 [cytosol]
(R-SCE-442630)
0.764
6
UniProt:Q12163 NBP2
0.761
7
UniProt:P34730 BMH2
1
BMH2 [cytosol]
(R-SCE-194368)
0.564
2
UniProt:Q08754 BUD7
0.553
2
UniProt:Q04439 MYO5
0.527
4
UniProt:P11484
17
HSPA6 [ficolin-1-rich granule lumen]
(R-SCE-6801512-4)
HSPA1A [ficolin-1-rich granule lumen]
(R-SCE-6801496-4)
HSPA1A [extracellular region]
(R-SCE-6805872-4)
HSPA6 [extracellular region]
(R-SCE-6806500-4)
HSPA6 [secretory granule lumen]
(R-SCE-6801472-4)
HSPA1L [cytosol]
(R-SCE-3371410-4)
HSPA2 [cytosol]
(R-SCE-3371408-4)
HSPA1A [cytosol]
(R-SCE-6792602-4)
HSPA1A [nucleoplasm]
(R-SCE-6792605-4)
HSPA2 [nucleoplasm]
(R-SCE-912480-4)
HSPA1L [nucleoplasm]
(R-SCE-5082367-4)
HSPA14 [nucleoplasm]
(R-SCE-5252082-4)
HSPA6 [nucleoplasm]
(R-SCE-5252088-4)
HSPA13 [nucleoplasm]
(R-SCE-5252009-4)
HSPA14 [cytosol]
(R-SCE-5251948-4)
HSPA13 [cytosol]
(R-SCE-5251981-4)
HSPA6 [cytosol]
(R-SCE-3371521-4)
0.527
3
UniProt:P15108
6
HSP90AA1 [secretory granule lumen]
(R-SCE-6801515-2)
HSP90AA1 [ficolin-1-rich granule lumen]
(R-SCE-6801470-2)
HSP90AA1 [extracellular region]
(R-SCE-3221946-2)
HSP90AA1 [plasma membrane]
(R-SCE-534996-2)
HSP90AA1 [nucleoplasm]
(R-SCE-5082401-2)
HSP90AA1 [cytosol]
(R-SCE-192864-2)
0.527
2
UniProt:P18851
3
STE4 [cytosol]
(R-SCE-6814200)
STE4 [cytosol]
(R-SCE-6814203)
STE4 [cytosol]
(R-SCE-6814204)
0.524
3
UniProt:P40073 SHO1
0.456
2
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