Reactome | MRC1 [nucleoplasm]

MRC1 [nucleoplasm]

Stable Identifier

R-SCE-176282

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

CLSPN, P25588

Locations in the PathwayBrowser for interactor UniProt:P53840

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External Reference Information

External Reference

UniProt:P25588

Gene Names

MRC1

Reference Genes

BioGPS Gene:850297 MRC1

ENSEMBL:YCL061C

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YCL061C MRC1

Monarch:850297 MRC1

NCBI Gene:850297 MRC1

SGD:YCL061C

Reference Transcript

RefSeq:NM_001178704.1 MRC1

Other Identifiers

1773972_at

6917_at

850297

GO:0000076

GO:0000228

GO:0000278

GO:0000723

GO:0000781

GO:0003674

GO:0005515

GO:0005575

GO:0005634

GO:0005694

GO:0006260

GO:0006281

GO:0006325

GO:0006348

GO:0006974

GO:0007059

GO:0007064

GO:0007095

GO:0008150

GO:0010997

GO:0023052

GO:0030466

GO:0031298

GO:0031509

GO:0031573

GO:0032200

GO:0033262

GO:0033314

GO:0034399

GO:0043570

GO:0043596

GO:0048285

GO:0048478

GO:0051052

GO:0051726

Participates

as a component of

as an input of

Loading of claspin onto DNA during replication origin firing (Saccharomyces cerevisiae)

Other forms of this molecule

MRC1 [nucleoplasm]

phospho-MRC1 [nucleoplasm]

Inferred From

CLSPN, MYC [nucleoplasm] (Homo sapiens)

CLSPN [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_009871.2

OpenTargets

ENSG00000260314

PRO

P25588

PDB

8B9C, 8B9B, 8B9A, 8XGC

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q08032	1	CDC45 [nucleoplasm] (R-SCE-68563)	0.688	4
UniProt:Q08496 DIA2			0.616	11
UniProt:P32485	20	phospho-p-T221,Y223-MAPK10 [nucleoplasm] (R-SCE-450311) phospho-p-T183,Y185-MAPK9 [nucleoplasm] (R-SCE-450319) phospho-p-T,Y-MAPK8 [nucleoplasm] (R-SCE-216349) phospho-p-T180,Y182-MAPK14 [nucleoplasm] (R-SCE-446227) phospho-p-T180,Y182-MAPK11 [nucleoplasm] (R-SCE-198741) phospho-p-T180,Y182-MAPK14 [cytosol] (R-SCE-428935) MAPK14 [cytosol] (R-SCE-428933) phospho-p-T221,Y223-MAPK10 [cytosol] (R-SCE-450214) phospho-p-T,Y-MAPK8 [cytosol] (R-SCE-194371) phospho-p-T183,Y185-MAPK9 [cytosol] (R-SCE-450293) MAPK9 [cytosol] (R-SCE-450355) MAPK10 [cytosol] (R-SCE-450352) MAPK8 [cytosol] (R-SCE-168141) MAPK12 [cytosol] (R-SCE-171025) MAPK13 [cytosol] (R-SCE-171012) MAPK11 [cytosol] (R-SCE-170989) phospho-p-T180,Y182-MAPK11 [cytosol] (R-SCE-171009) phospho-p-T180,Y182-MAPK13 [cytosol] (R-SCE-171022) phospho-p-T183,Y185-MAPK12 [cytosol] (R-SCE-171021) MAPK14 [ficolin-1-rich granule lumen] (R-SCE-6803280)	0.593	4
UniProt:P53919 NAF1			0.573	2
UniProt:P53840	1	TOF1 [nucleoplasm] (R-SCE-5684982)	0.564	4

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