Reactome | phospho-HOG1 [nucleoplasm]

phospho-HOG1 [nucleoplasm]

Stable Identifier

R-SCE-198741

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

p-T180,Y182-MAPK11, P32485

Locations in the PathwayBrowser

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Immune System (Saccharomyces cerevisiae)

- Cytokine Signaling in Immune system (Saccharomyces cerevisiae)
  - Signaling by Interleukins (Saccharomyces cerevisiae)
    - Interleukin-17 signaling (Saccharomyces cerevisiae)
      - MAP kinase activation (Saccharomyces cerevisiae)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Saccharomyces cerevisiae)
        
        Activation of the AP-1 family of transcription factors (Saccharomyces cerevisiae)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Saccharomyces cerevisiae)
        
        Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-p38 MAPK alpha/beta [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of p-T180,Y182-MAPK11 [nucleoplasm] (Saccharomyces cerevisiae)
        
        phospho-HOG1 [nucleoplasm] (Saccharomyces cerevisiae)
- Innate Immune System (Saccharomyces cerevisiae)
  - Toll-like Receptor Cascades (Saccharomyces cerevisiae)
    - Toll Like Receptor 10 (TLR10) Cascade (Saccharomyces cerevisiae)
      - MyD88 cascade initiated on plasma membrane (Saccharomyces cerevisiae)
        
        MAP kinase activation (Saccharomyces cerevisiae)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Saccharomyces cerevisiae)
        
        Activation of the AP-1 family of transcription factors (Saccharomyces cerevisiae)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Saccharomyces cerevisiae)
        
        Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-p38 MAPK alpha/beta [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of p-T180,Y182-MAPK11 [nucleoplasm] (Saccharomyces cerevisiae)
        
        phospho-HOG1 [nucleoplasm] (Saccharomyces cerevisiae)
    - Toll Like Receptor 2 (TLR2) Cascade (Saccharomyces cerevisiae)
      - Toll Like Receptor TLR1:TLR2 Cascade (Saccharomyces cerevisiae)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Saccharomyces cerevisiae)
        
        MAP kinase activation (Saccharomyces cerevisiae)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Saccharomyces cerevisiae)
        
        Activation of the AP-1 family of transcription factors (Saccharomyces cerevisiae)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Saccharomyces cerevisiae)
        
        Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-p38 MAPK alpha/beta [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of p-T180,Y182-MAPK11 [nucleoplasm] (Saccharomyces cerevisiae)
        
        phospho-HOG1 [nucleoplasm] (Saccharomyces cerevisiae)
      - Toll Like Receptor TLR6:TLR2 Cascade (Saccharomyces cerevisiae)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Saccharomyces cerevisiae)
        
        MAP kinase activation (Saccharomyces cerevisiae)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Saccharomyces cerevisiae)
        
        Activation of the AP-1 family of transcription factors (Saccharomyces cerevisiae)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Saccharomyces cerevisiae)
        
        Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-p38 MAPK alpha/beta [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of p-T180,Y182-MAPK11 [nucleoplasm] (Saccharomyces cerevisiae)
        
        phospho-HOG1 [nucleoplasm] (Saccharomyces cerevisiae)
    - Toll Like Receptor 3 (TLR3) Cascade (Saccharomyces cerevisiae)
      - MAP kinase activation (Saccharomyces cerevisiae)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Saccharomyces cerevisiae)
        
        Activation of the AP-1 family of transcription factors (Saccharomyces cerevisiae)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Saccharomyces cerevisiae)
        
        Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-p38 MAPK alpha/beta [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of p-T180,Y182-MAPK11 [nucleoplasm] (Saccharomyces cerevisiae)
        
        phospho-HOG1 [nucleoplasm] (Saccharomyces cerevisiae)
    - Toll Like Receptor 4 (TLR4) Cascade (Saccharomyces cerevisiae)
      - MyD88-independent TLR4 cascade (Saccharomyces cerevisiae)
        
        TRIF(TICAM1)-mediated TLR4 signaling (Saccharomyces cerevisiae)
        
        MAP kinase activation (Saccharomyces cerevisiae)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Saccharomyces cerevisiae)
        
        Activation of the AP-1 family of transcription factors (Saccharomyces cerevisiae)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Saccharomyces cerevisiae)
        
        Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-p38 MAPK alpha/beta [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of p-T180,Y182-MAPK11 [nucleoplasm] (Saccharomyces cerevisiae)
        
        phospho-HOG1 [nucleoplasm] (Saccharomyces cerevisiae)
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Saccharomyces cerevisiae)
        
        MAP kinase activation (Saccharomyces cerevisiae)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Saccharomyces cerevisiae)
        
        Activation of the AP-1 family of transcription factors (Saccharomyces cerevisiae)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Saccharomyces cerevisiae)
        
        Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-p38 MAPK alpha/beta [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of p-T180,Y182-MAPK11 [nucleoplasm] (Saccharomyces cerevisiae)
        
        phospho-HOG1 [nucleoplasm] (Saccharomyces cerevisiae)
    - Toll Like Receptor 5 (TLR5) Cascade (Saccharomyces cerevisiae)
      - MyD88 cascade initiated on plasma membrane (Saccharomyces cerevisiae)
        
        MAP kinase activation (Saccharomyces cerevisiae)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Saccharomyces cerevisiae)
        
        Activation of the AP-1 family of transcription factors (Saccharomyces cerevisiae)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Saccharomyces cerevisiae)
        
        Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-p38 MAPK alpha/beta [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of p-T180,Y182-MAPK11 [nucleoplasm] (Saccharomyces cerevisiae)
        
        phospho-HOG1 [nucleoplasm] (Saccharomyces cerevisiae)
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Saccharomyces cerevisiae)
      - MyD88 dependent cascade initiated on endosome (Saccharomyces cerevisiae)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Saccharomyces cerevisiae)
        
        MAP kinase activation (Saccharomyces cerevisiae)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Saccharomyces cerevisiae)
        
        Activation of the AP-1 family of transcription factors (Saccharomyces cerevisiae)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Saccharomyces cerevisiae)
        
        Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-p38 MAPK alpha/beta [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of p-T180,Y182-MAPK11 [nucleoplasm] (Saccharomyces cerevisiae)
        
        phospho-HOG1 [nucleoplasm] (Saccharomyces cerevisiae)
    - Toll Like Receptor 9 (TLR9) Cascade (Saccharomyces cerevisiae)
      - MyD88 dependent cascade initiated on endosome (Saccharomyces cerevisiae)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Saccharomyces cerevisiae)
        
        MAP kinase activation (Saccharomyces cerevisiae)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Saccharomyces cerevisiae)
        
        Activation of the AP-1 family of transcription factors (Saccharomyces cerevisiae)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Saccharomyces cerevisiae)
        
        Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-p38 MAPK alpha/beta [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of p-T180,Y182-MAPK11 [nucleoplasm] (Saccharomyces cerevisiae)
        
        phospho-HOG1 [nucleoplasm] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P32485

Gene Names

HOG1

Reference Genes

BioGPS Gene:850803 HOG1

ENSEMBL:YLR113W

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YLR113W HOG1

Monarch:850803 HOG1

NCBI Gene:850803 HOG1

SGD:YLR113W

Reference Transcript

RefSeq:NM_001182000.1 HOG1

Other Identifiers

10232_at

1775699_at

850803

GO:0003674

GO:0003682

GO:0004672

GO:0004707

GO:0005516

GO:0005524

GO:0005575

GO:0005634

GO:0005737

GO:0006260

GO:0006351

GO:0006366

GO:0006468

GO:0006970

GO:0006972

GO:0006979

GO:0007186

GO:0007231

GO:0008150

GO:0009408

GO:0016241

GO:0016301

GO:0016740

GO:0023052

GO:0033262

GO:0034599

GO:0034605

GO:0042221

GO:0043167

GO:0045944

GO:0046685

GO:0051403

GO:0051726

GO:0061392

GO:0061393

GO:0071310

GO:0071470

Participant Of

hasMember

Homologues of p-T180,Y182-MAPK11 [nucleoplasm]

Other forms of this molecule

HOG1 [cytosol]

HOG1 [nucleoplasm]

HOG1 [cytosol]

phospho-HOG1 [cytosol]

phospho-HOG1 [nucleoplasm]

HOG1 [nucleoplasm]

phospho-HOG1 [nucleoplasm]

phospho-HOG1 [cytosol]

HOG1 [cytosol]

phospho-HOG1 [cytosol]

HOG1 [cytosol]

phospho-HOG1 [cytosol]

phospho-HOG1 [nucleoplasm]

phospho-HOG1 [cytosol]

HOG1 [cytosol]

phospho-HOG1 [cytosol]

HOG1 [cytosol]

phospho-HOG1 [cytosol]

HOG1 [secretory granule lumen]

HOG1 [extracellular region]

HOG1 [ficolin-1-rich granule lumen]

HOG1 [nucleoplasm]

Inferred From

p-T180,Y182-MAPK11 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

O-phospho-L-threonine at 180 (in Homo sapiens)

Coordinate

180

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Name

O4'-phospho-L-tyrosine at 182 (in Homo sapiens)

Coordinate

182

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_013214.1

IntEnz

2.7.11.24

PRO

P32485

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