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phospho-2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane]
Stable Identifier
R-SCE-202139
Type
Protein [EntityWithAccessionedSequence]
Species
Saccharomyces cerevisiae
Compartment
plasma membrane
Synonyms
P16603
Locations in the PathwayBrowser
Expand all
Metabolism (Saccharomyces cerevisiae)
Metabolism of nitric oxide: NOS3 activation and regulation (Saccharomyces cerevisiae)
eNOS activation (Saccharomyces cerevisiae)
AKT1 phosphorylates eNOS (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
phospho-2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane] (Saccharomyces cerevisiae)
BH2 binding can lead to eNOS uncoupling (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
phospho-2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
phospho-2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane] (Saccharomyces cerevisiae)
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
phospho-2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
phospho-2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane] (Saccharomyces cerevisiae)
Uncoupled eNOS favours the formation of superoxide (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
phospho-2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane] (Saccharomyces cerevisiae)
eNOS synthesizes NO (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
phospho-2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane] (Saccharomyces cerevisiae)
Metabolism of vitamins and cofactors (Saccharomyces cerevisiae)
Metabolism of cofactors (Saccharomyces cerevisiae)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Saccharomyces cerevisiae)
BH2 binding can lead to eNOS uncoupling (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
phospho-2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
phospho-2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane] (Saccharomyces cerevisiae)
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
phospho-2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
phospho-2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane] (Saccharomyces cerevisiae)
Signal Transduction (Saccharomyces cerevisiae)
Signaling by Nuclear Receptors (Saccharomyces cerevisiae)
ESR-mediated signaling (Saccharomyces cerevisiae)
Extra-nuclear estrogen signaling (Saccharomyces cerevisiae)
eNOS synthesizes NO (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
phospho-2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane] (Saccharomyces cerevisiae)
Signaling by Receptor Tyrosine Kinases (Saccharomyces cerevisiae)
Signaling by VEGF (Saccharomyces cerevisiae)
VEGFA-VEGFR2 Pathway (Saccharomyces cerevisiae)
VEGFR2 mediated vascular permeability (Saccharomyces cerevisiae)
AKT1 phosphorylates eNOS (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
phospho-2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane] (Saccharomyces cerevisiae)
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
phospho-2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
phospho-2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane] (Saccharomyces cerevisiae)
eNOS synthesizes NO (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
phospho-2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane] (Saccharomyces cerevisiae)
External Reference Information
External Reference
UniProt:P16603
Reference Genes
BioGPS Gene:856438
ENSEMBL:YHR042W
KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YHR042W
Monarch:856438
NCBI Gene:856438
SGD:YHR042W
Reference Transcript
RefSeq:NM_001179172.1
Other Identifiers
1776023_at
4471_at
856438
GO:0003674
GO:0003958
GO:0003959
GO:0005575
GO:0005737
GO:0005739
GO:0005740
GO:0005741
GO:0005783
GO:0005789
GO:0005829
GO:0005886
GO:0006091
GO:0006629
GO:0006694
GO:0006696
GO:0008150
GO:0008202
GO:0009055
GO:0010181
GO:0012505
GO:0016020
GO:0016021
GO:0016126
GO:0016491
GO:0022900
GO:0043167
GO:0050660
GO:0050661
Participates
as a component of
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
Other forms of this molecule
NOS2 [peroxisomal matrix]
NOS1 [cytosol]
NOS2 [cytosol]
2xPalmC-MyrG-NOS3 [plasma membrane]
MyrG-NOS3 [Golgi membrane]
2xPalmC-MyrG-NOS3 [Golgi membrane]
MyrG-NOS3 [cytosol]
NOS3 [cytosol]
Inferred From
2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 1177 (in Homo sapiens)
Coordinate
1177
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
S-palmitoyl-L-cysteine at 15 (in Homo sapiens)
Coordinate
15
PsiMod Name
S-palmitoyl-L-cysteine [MOD:00115]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine.
Name
S-palmitoyl-L-cysteine at 26 (in Homo sapiens)
Coordinate
26
PsiMod Name
S-palmitoyl-L-cysteine [MOD:00115]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine.
Name
N-myristoylglycine at 2 (in Homo sapiens)
Coordinate
2
PsiMod Name
N-myristoylglycine [MOD:00068]
PsiMod Definition
A protein modification that effectively converts a glycine residue to N-myristoylglycine.
Cross References
RefSeq
NP_011908.1
PRO
P16603
PDB
2BN4
,
3FJO
,
2BPO
,
2BF4
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P10591
17
SSA1 [ficolin-1-rich granule lumen]
(R-SCE-6801512-2)
SSA1 [ficolin-1-rich granule lumen]
(R-SCE-6801496-2)
SSA1 [extracellular region]
(R-SCE-6805872-2)
SSA1 [extracellular region]
(R-SCE-6806500-2)
SSA1 [secretory granule lumen]
(R-SCE-6801472-2)
SSA1 [cytosol]
(R-SCE-3371410-2)
SSA1 [cytosol]
(R-SCE-3371408-2)
SSA1 [cytosol]
(R-SCE-6792602-2)
SSA1 [nucleoplasm]
(R-SCE-6792605-2)
SSA1 [nucleoplasm]
(R-SCE-912480-2)
SSA1 [nucleoplasm]
(R-SCE-5082367-2)
SSA1 [nucleoplasm]
(R-SCE-5252082-2)
SSA1 [nucleoplasm]
(R-SCE-5252088-2)
SSA1 [nucleoplasm]
(R-SCE-5252009-2)
SSA1 [cytosol]
(R-SCE-5251948-2)
SSA1 [cytosol]
(R-SCE-5251981-2)
SSA1 [cytosol]
(R-SCE-3371521-2)
0.527
2
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