Reactome | ANB1 [cytosol]

ANB1 [cytosol]

Stable Identifier

R-SCE-204650

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

Hyp-K50-EIF5A2, P19211

Locations in the PathwayBrowser

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Metabolism of proteins (Saccharomyces cerevisiae)

- Post-translational protein modification (Saccharomyces cerevisiae)
  - Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Saccharomyces cerevisiae)
    - Hypusine synthesis from eIF5A-lysine (Saccharomyces cerevisiae)
      - DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Saccharomyces cerevisiae)
        
        Hyp-K50-EIF5A [cytosol] (Saccharomyces cerevisiae)
        
        Homologues of Hyp-K50-EIF5A2 [cytosol] (Saccharomyces cerevisiae)
        
        ANB1 [cytosol] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P19211

Gene Names

ANB1

Reference Genes

BioGPS Gene:853506 ANB1

ENSEMBL:YJR047C

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YJR047C ANB1

Monarch:853506 ANB1

NCBI Gene:853506 ANB1

SGD:YJR047C

Reference Transcript

RefSeq:NM_001181705.3 ANB1

Other Identifiers

10976_at

1779407_at

853506

GO:0003674

GO:0003723

GO:0003746

GO:0005575

GO:0005737

GO:0005840

GO:0006412

GO:0006414

GO:0006417

GO:0006452

GO:0008135

GO:0008150

GO:0022626

GO:0043022

GO:0045901

GO:0045905

Participates

as a member of

Homologues of Hyp-K50-EIF5A2 [cytosol] (Saccharomyces cerevisiae)

Other forms of this molecule

ANB1 [cytosol]

Inferred From

Hyp-K50-EIF5A2 [cytosol] (Homo sapiens)

Modified Residues

Name

hypusine at 50 (in Homo sapiens)

Coordinate

PsiMod Name

hypusine [MOD:00125]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to hypusine, N6-(4-amino-2-hydroxybutyl)-L-lysine.

Cross References

RefSeq

NP_012581.3

PRO

P19211

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