Reactome | phospho-p-T,Y-MAPK8 [nucleoplasm]

phospho-p-T,Y-MAPK8 [nucleoplasm]

Stable Identifier

R-SCE-216349

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

P32485

Locations in the PathwayBrowser for interactor UniProt:P25588

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External Reference Information

External Reference

UniProt:P32485

Reference Genes

BioGPS Gene:850803

ENSEMBL:YLR113W

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YLR113W

Monarch:850803

NCBI Gene:850803

SGD:YLR113W

Reference Transcript

RefSeq:NM_001182000.1

Other Identifiers

10232_at

1775699_at

850803

GO:0000166

GO:0000278

GO:0001100

GO:0003674

GO:0003682

GO:0004672

GO:0004674

GO:0004707

GO:0005515

GO:0005516

GO:0005524

GO:0005575

GO:0005634

GO:0005737

GO:0006260

GO:0006351

GO:0006357

GO:0006366

GO:0006468

GO:0006970

GO:0006972

GO:0006979

GO:0007186

GO:0007231

GO:0008150

GO:0009408

GO:0016241

GO:0016301

GO:0016310

GO:0016740

GO:0023052

GO:0033262

GO:0034599

GO:0034605

GO:0042221

GO:0043167

GO:0045944

GO:0046685

GO:0048285

GO:0051052

GO:0051403

GO:0051726

GO:0061392

GO:0061393

GO:0071310

GO:0071470

GO:0106310

Participates

as an output of

Active JNK moves to the nucleus and phosphorylates different transcription factors (Saccharomyces cerevisiae)

as a member of

p-MAPK8,9,10 [nucleoplasm] (Saccharomyces cerevisiae)

Other forms of this molecule

phospho-p-T221,Y223-MAPK10 [nucleoplasm]

phospho-p-T183,Y185-MAPK9 [nucleoplasm]

phospho-p-T180,Y182-MAPK14 [nucleoplasm]

phospho-p-T180,Y182-MAPK11 [nucleoplasm]

phospho-p-T180,Y182-MAPK14 [cytosol]

MAPK14 [cytosol]

phospho-p-T221,Y223-MAPK10 [cytosol]

phospho-p-T,Y-MAPK8 [cytosol]

phospho-p-T183,Y185-MAPK9 [cytosol]

MAPK9 [cytosol]

MAPK10 [cytosol]

MAPK8 [cytosol]

MAPK12 [cytosol]

MAPK13 [cytosol]

MAPK11 [cytosol]

phospho-p-T180,Y182-MAPK11 [cytosol]

phospho-p-T180,Y182-MAPK13 [cytosol]

phospho-p-T183,Y185-MAPK12 [cytosol]

MAPK14 [ficolin-1-rich granule lumen]

MAPK14 [extracellular region]

MAPK14 [secretory granule lumen]

MAPK12 [nucleoplasm]

Inferred From

p-T,Y-MAPK8 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

O-phospho-L-threonine at unknown position

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Name

O4'-phospho-L-tyrosine at unknown position

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_013214.1

PRO

P32485

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P38623	1	CAMK1 [cytosol] (R-SCE-9619207)	0.819	8
UniProt:P38634 SIC1			0.639	4
UniProt:Q03213 HOT1			0.613	4
UniProt:P25588	5	MRC1 [nucleoplasm] (R-SCE-6783087) MRC1 [nucleoplasm] (R-SCE-351929) MRC1 [nucleoplasm] (R-SCE-351935) MRC1 [nucleoplasm] (R-SCE-176282) phospho-MRC1 [nucleoplasm] (R-SCE-176296)	0.593	4
UniProt:P38622	2	phospho-p-T68-CHEK2 [nucleoplasm] (R-SCE-113825) phospho-p-S,3T-CHEK2 [nucleoplasm] (R-SCE-5683784)	0.547	2
UniProt:P02829	11	HSP90AB1 [secretory granule lumen] (R-SCE-6801477) HSP90AA1 [secretory granule lumen] (R-SCE-6801515) HSP90AB1 [extracellular region] (R-SCE-6806463) HSP90AA1 [ficolin-1-rich granule lumen] (R-SCE-6801470) HSP90AB1 [ficolin-1-rich granule lumen] (R-SCE-6801491) HSP90AA1 [plasma membrane] (R-SCE-534996) HSP90AA1 [extracellular region] (R-SCE-3221946) HSP90AB1 [cytosol] (R-SCE-419617) HSP90AA1 [nucleoplasm] (R-SCE-5082401) HSP90AB1 [nucleoplasm] (R-SCE-5082399) HSP90AA1 [cytosol] (R-SCE-192864)	0.547	2
UniProt:P34244 HSL1			0.544	2
UniProt:Q01477	2	UBP3 [nucleoplasm] (R-SCE-3222218) UBP3 [cytosol] (R-SCE-6782974)	0.544	3
UniProt:P06784	7	phospho-p-S,218, S222,T292 MAP2K1 [cytosol] (R-SCE-5674490) phospho-p-S,T-MAP2K2 [cytosol] (R-SCE-109848) phospho-p-T286,T292-MAP2K1 [cytosol] (R-SCE-112374) phospho-p-S218,S222,T286,T292-MAP2K1 [cytosol] (R-SCE-112339) MAP2K1 [cytosol] (R-SCE-59502) phospho-p-S222,S226-MAP2K2 [cytosol] (R-SCE-169292) phospho-p-S218,S222-MAP2K1 [cytosol] (R-SCE-109837)	0.499	2
UniProt:P19454 CKA2	5	CKA2 [nucleoplasm] (R-SCE-6790631) CSNK2A1 [nucleoplasm] (R-SCE-6805057-2) CSNK2A2 [nucleoplasm] (R-SCE-6805065-2) CSNK2A2 [cytosol] (R-SCE-201721-2) CSNK2A1 [cytosol] (R-SCE-201713-2)	0.462	3
UniProt:P15790 CKA1	5	CKA1 [nucleoplasm] (R-SCE-6790643) CSNK2A1 [nucleoplasm] (R-SCE-6805057) CSNK2A2 [nucleoplasm] (R-SCE-6805065) CSNK2A2 [cytosol] (R-SCE-201721) CSNK2A1 [cytosol] (R-SCE-201713)	0.462	2

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