Reactome | SMT3 [nucleoplasm]

SMT3 [nucleoplasm]

Stable Identifier

R-SCE-2990831

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

SUMO1(2-101), Q12306

Locations in the PathwayBrowser for interactor UniProt:Q03718 NSE5

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External Reference Information

External Reference

UniProt:Q12306

Gene Names

SMT3

Reference Genes

BioGPS Gene:852122 SMT3

ENSEMBL:YDR510W

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YDR510W SMT3

Monarch:852122 SMT3

NCBI Gene:852122 SMT3

SGD:YDR510W

Reference Transcript

RefSeq:NM_001180818.1 SMT3

Other Identifiers

1776081_at

5979_at

852122

GO:0000794

GO:0003674

GO:0005515

GO:0005575

GO:0005634

GO:0005694

GO:0005737

GO:0005856

GO:0005938

GO:0005940

GO:0008150

GO:0016925

GO:0018193

GO:0019899

GO:0031386

GO:0042802

GO:0044389

GO:0070647

Participates

as an input of

SENP1,2,5 proteolytically process SUMO1 (Saccharomyces cerevisiae)

Other forms of this molecule

SMT3 [cytosol]

SMT3 [nucleoplasm]

Inferred From

SUMO1(2-101) [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_010798.1

PRO

Q12306

PDB

3V60, 6Q2S, 7ZWL, 7P9Y, 3QHT, 5V8T, 5JNE, 5KLX, 3UQA, 7P9P, 5YCA, 7LTO, 5D6J, 7P9L, 4FN2, 4GGQ, 3UF8, 1EUV, 7SDE, 6VW2, 6RPQ, 8DMB, 1L2N, 6CFP, 6UKY, 4GIV, 7O2W, 6UKX, 6VEL, 8B7F, 3V62, 7P7W, 7ZHS, 3UQB, 6P81, 3PGE, 6UKZ, 6O49, 3V61, 6UL0, 6UKU, 6O4A, 7P47, 4G50, 6UKM, 3VAW, 2EKE, 6UKW, 5YC2, 8R1F, 6UKV, 7P7I, 8R1G, 3TIX, 7PA1

Interactors (33)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P50623	5	UBC9 [nucleoplasm] (R-SCE-4085358) UBC9 [cytosol] (R-SCE-4656944) UBC9 [cytosol] (R-SCE-4656909) UBC9 [nucleoplasm] (R-SCE-3730617) UBC9 [nucleoplasm] (R-SCE-912481)	0.757	4
UniProt:Q08204	1	SMC5 [nucleoplasm] (R-SCE-2993751)	0.728	5
UniProt:P14291 RED1			0.704	9
UniProt:P12954 SRS2			0.704	4
UniProt:P15873	5	POL30 [nucleoplasm] (R-SCE-4615861) POL30 [nucleoplasm] (R-SCE-8943000) POL30 [nucleoplasm] (R-SCE-5653768) POL30 [nucleoplasm] (R-SCE-5651986) POL30 [nucleoplasm] (R-SCE-68439)	0.698	6
UniProt:Q12050 ELG1			0.683	11
UniProt:Q12306	5	SMT3 [cytosol] (R-SCE-4656941) SMT3 [nucleoplasm] (R-SCE-3730622) SMT3 [nucleoplasm] (R-SCE-3730616) SMT3 [nucleoplasm] (R-SCE-877304) SMT3 [nucleoplasm] (R-SCE-2990831)	0.681	3
UniProt:P06778	3	RAD52 [nucleoplasm] (R-SCE-4568909) RAD52 [nucleoplasm] (R-SCE-62639) phospho-RAD52 [nucleoplasm] (R-SCE-5686588)	0.589	2
UniProt:P53044	2	UFD1 [nucleoplasm] (R-SCE-5654993) UFD1 [cytosol] (R-SCE-9668519)	0.567	3
UniProt:P25694	7	VCP [cytosol] (R-SCE-1181251) VCP [ficolin-1-rich granule lumen] (R-SCE-6800425) VCP [extracellular region] (R-SCE-6806191) VCP [secretory granule lumen] (R-SCE-6801039) VCP [azurophil granule lumen] (R-SCE-6800438) VCP [nucleoplasm] (R-SCE-5643745) Me3K315-VCP [cytosol] (R-SCE-8932209)	0.567	3
UniProt:P52488	2	SUMO1-C173-UBA2 [nucleoplasm] (R-SCE-3730628) UBA2 [nucleoplasm] (R-SCE-947696)	0.558	2
UniProt:B0QYN7 B0QYN7			0.556	3
UniProt:P63279 UBE2I	9	monoSUMO1-K14-UBE2I [nucleoplasm] (R-HSA-4085358) UBE2I [nuclear envelope] (R-HSA-4655408) SUMO2-C93-UBE2I [cytosol] (R-HSA-4656944) SUMO3-C93-UBE2I [nucleoplasm] (R-HSA-3730629) UBE2I [cytosol] (R-HSA-4655342) SUMO1-C93-UBE2I [cytosol] (R-HSA-4656909) SUMO2-C93-UBE2I [nucleoplasm] (R-HSA-3730619) SUMO1-C93-UBE2I [nucleoplasm] (R-HSA-3730617) UBE2I [nucleoplasm] (R-HSA-912481)	0.556	3
UniProt:P23497-2 SP100			0.556	3
UniProt:Q9HCK0 ZBT26			0.556	3
UniProt:Q03718 NSE5			0.553	2
UniProt:P38319 TYDP1			0.553	2
UniProt:Q04110 ECM11			0.553	2
UniProt:P32828 SLX5			0.553	2
UniProt:P35187	1	BLM [nucleoplasm] (R-SCE-174881)	0.527	3
UniProt:P07271 PIF1			0.524	2
UniProt:P53091 MCM6	2	yMcm6 [nucleoplasm] (R-SCE-169504) MCM6 [nucleoplasm] (R-SCE-68553)	0.524	2
UniProt:P32797 CDC13			0.524	3
UniProt:Q04437	3	YKU80 [extracellular region] (R-SCE-6806530) YKU80 [secretory granule lumen] (R-SCE-6801297) YKU80 [nucleoplasm] (R-SCE-58274)	0.524	2
UniProt:P30665 MCM4	2	yMcm4 [nucleoplasm] (R-SCE-169496) MCM4 [nucleoplasm] (R-SCE-68549)	0.524	2
UniProt:P32807	4	YKU70 [secretory granule lumen] (R-SCE-6801312) YKU70 [extracellular region] (R-SCE-6806444) YKU70 [ficolin-1-rich granule lumen] (R-SCE-6801300) YKU70 [nucleoplasm] (R-SCE-58272)	0.524	2
UniProt:P38132 MCM7	2	yMcm7 [nucleoplasm] (R-SCE-169505) MCM7 [nucleoplasm] (R-SCE-68555)	0.524	2
UniProt:P29496 MCM5	2	yMcm5 [nucleoplasm] (R-SCE-169511) MCM5 [nucleoplasm] (R-SCE-68551)	0.524	3
UniProt:P24279 MCM3	2	yMcm3 [nucleoplasm] (R-SCE-169513) MCM3 [nucleoplasm] (R-SCE-68546)	0.524	2
UniProt:P29469 MCM2	2	MCM2 [nucleoplasm] (R-SCE-68557) yMcm2 [nucleoplasm] (R-SCE-169497)	0.524	2
UniProt:P31111	5	ZIP1 [cytosol] (R-SCE-1449561-2) ZIP1 [cytosol] (R-SCE-419176-2) ZIP1 [cytosol] (R-SCE-419173-2) ZIP1 [cytosol] (R-SCE-420855-2) ZIP1 [cytosol] (R-SCE-419174-2)	0.502	2
UniProt:P32908	4	SMC1A [cytosol] (R-SCE-2484798) SMC1A [chromosome] (R-SCE-1638774) SMC1A [chromosome, centromeric region] (R-SCE-2466015) SMC1A [nucleoplasm] (R-SCE-64561)	0.499	2
UniProt:P25454	2	RAD51 [nucleoplasm] (R-SCE-62637) phospho-p-T309-RAD51 [nucleoplasm] (R-SCE-5685231)	0.482	2

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