Reactome | SMC5 [nucleoplasm]

SMC5 [nucleoplasm]

Stable Identifier

R-SCE-2993751

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

SMC5, Q08204

Locations in the PathwayBrowser

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Metabolism of proteins (Saccharomyces cerevisiae)

- Post-translational protein modification (Saccharomyces cerevisiae)
  - SUMOylation (Saccharomyces cerevisiae)
    - SUMO E3 ligases SUMOylate target proteins (Saccharomyces cerevisiae)
      - SUMOylation of DNA damage response and repair proteins (Saccharomyces cerevisiae)
        
        SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 (Saccharomyces cerevisiae)
        
        SMC5-SMC6 Complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        SMC5 [nucleoplasm] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:Q08204

Gene Names

SMC5

Reference Genes

BioGPS Gene:854123 SMC5

ENSEMBL:YOL034W

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YOL034W SMC5

Monarch:854123 SMC5

NCBI Gene:854123 SMC5

SGD:YOL034W

Reference Transcript

RefSeq:NM_001183288.1 SMC5

Other Identifiers

1775635_at

854123

8573_at

GO:0000724

GO:0000725

GO:0003674

GO:0003677

GO:0003684

GO:0003697

GO:0005524

GO:0005575

GO:0005634

GO:0005694

GO:0006281

GO:0006310

GO:0006974

GO:0007059

GO:0007062

GO:0008150

GO:0016787

GO:0016887

GO:0016925

GO:0018193

GO:0030915

GO:0043167

GO:0051304

GO:0070647

GO:0071139

Participates

as a component of

SMC5-SMC6 Complex [nucleoplasm] (Saccharomyces cerevisiae)

Inferred From

SMC5 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_014608.1

OpenTargets

ENSG00000198887

PRO

Q08204

PDB

3HTK

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q12306	31	SMT3 [nucleoplasm] (R-SCE-3968375) SMT3 [nucleoplasm] (R-SCE-4085334) SMT3 [nuclear envelope] (R-SCE-4551627) SMT3 [nucleoplasm] (R-SCE-4086096) SMT3 [nucleoplasm] (R-SCE-3900210) SMT3 [nucleoplasm] (R-SCE-3900212) SMT3 [nucleoplasm] (R-SCE-4086058) SMT3 [nucleoplasm] (R-SCE-4090362) SMT3 [nucleoplasm] (R-SCE-4641311) SMT3 [nucleoplasm] (R-SCE-4641306) SMT3 [nucleoplasm] (R-SCE-4641341) SMT3 [nucleoplasm] (R-SCE-4615836) SMT3 [nucleoplasm] (R-SCE-3826645) SMT3 [nucleoplasm] (R-SCE-3826574) SMT3 [nucleoplasm] (R-SCE-4568857) SMT3 [nucleoplasm] (R-SCE-4570452) SMT3 [nucleoplasm] (R-SCE-3730731) SMT3 [nucleoplasm] (R-SCE-3730738) SMT3 [nucleoplasm] (R-SCE-3968396) SMT3 [nucleoplasm] (R-SCE-4570515) SMT3 [nucleoplasm] (R-SCE-4570462) SMT3 [nucleoplasm] (R-SCE-4616028) SMT3 [nucleoplasm] (R-SCE-4616032) SMT3 [nucleoplasm] (R-SCE-4615961) SMT3 [nucleoplasm] (R-SCE-4615956) SMT3 [nucleoplasm] (R-SCE-4570549) SMT3 [nucleoplasm] (R-SCE-3730796) SMT3 [nucleoplasm] (R-SCE-2990831) SMT3 [nucleoplasm] (R-SCE-877304) SMT3 [nucleoplasm] (R-SCE-3730616) SMT3 [nucleoplasm] (R-SCE-3730622)	0.728	5

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