Reactome | USP10 [nucleoplasm]

USP10 [nucleoplasm]

Stable Identifier

R-SCE-3222218

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

Q01477

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q01477

Reference Genes

BioGPS Gene:856895

ENSEMBL:YER151C

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YER151C

Monarch:856895

NCBI Gene:856895

SGD:YER151C

Reference Transcript

RefSeq:NM_001179041.3

Other Identifiers

2QIY

4932.YER151C

AAA35191.1

AAB64678.1

DAA07812.1

EntrezGene:856895

EntrezGene:UBP3

GO:0003674

GO:0003723

GO:0003729

GO:0004843

GO:0005575

GO:0005737

GO:0006511

GO:0006970

GO:0008150

GO:0008233

GO:0016579

GO:0016787

GO:0034517

GO:0036459

GO:0047484

GO:0048193

GO:0051049

GO:0051603

GO:0060628

GO:0070647

GO:1990861

IPR001394

IPR018200

IPR028889

IPR038765

NM_001179041.3

NP_011078.3

PF00443

UPI00001379DE

YER151C

YER151C_mRNA

Participant Of

input

USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA

hasComponent

USP10:DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm]

Other forms of this molecule

USP37 [nucleoplasm]

USP10 [cytosol]

Inferred From

USP10 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_011078.3

IntEnz

3.4.19.12

PRO

Q01477

PDB

2QIY

Interactors (33)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P53741 BRE5			0.916	31
UniProt:P25694	7	VCP [ficolin-1-rich granule lumen] (R-SCE-6800425) VCP [cytosol] (R-SCE-1181251) VCP [extracellular region] (R-SCE-6806191) VCP [secretory granule lumen] (R-SCE-6801039) VCP [azurophil granule lumen] (R-SCE-6800438) VCP [nucleoplasm] (R-SCE-5643745) Me3K315-VCP [cytosol] (R-SCE-8932209)	0.632	4
UniProt:P36037	1	FBXW7 [cytosol] (R-SCE-391304)	0.632	4
UniProt:P39015 STM1			0.564	3
UniProt:P53141	4	phospho-p-S20-MYL6B [cytosol] (R-SCE-445763) MYL6B [cytosol] (R-SCE-445776) phospho-p-S20-MYL6 [cytosol] (R-SCE-445778) MYL6 [cytosol] (R-SCE-419186)	0.564	3
UniProt:P32485	16	MAPK14 [secretory granule lumen] (R-SCE-6803300) MAPK12 [nucleoplasm] (R-SCE-448833) MAPK14 [extracellular region] (R-SCE-6806453) MAPK14 [ficolin-1-rich granule lumen] (R-SCE-6803280) phospho-p-T183,Y185-MAPK12 [cytosol] (R-SCE-171021) phospho-p-T180,Y182-MAPK13 [cytosol] (R-SCE-171022) MAPK11 [cytosol] (R-SCE-170989) MAPK13 [cytosol] (R-SCE-171012) MAPK12 [cytosol] (R-SCE-171025) phospho-p-T180,Y182-MAPK11 [cytosol] (R-SCE-171009) MAPK11 [nucleoplasm] (R-SCE-203790) MAPK14 [nucleoplasm] (R-SCE-446223) phospho-p-T180,Y182-MAPK11 [nucleoplasm] (R-SCE-198741) phospho-p-T180,Y182-MAPK14 [nucleoplasm] (R-SCE-446227) MAPK14 [cytosol] (R-SCE-428933) phospho-p-T180,Y182-MAPK14 [cytosol] (R-SCE-428935)	0.544	3
UniProt:P41940 MPG1			0.527	2
UniProt:P33442 RPS1A	3	phospho-p-S418-CYLD [cytosol] (R-SCE-5212667-2) RPS1A [cytosol] (R-SCE-9633154) CYLD [cytosol] (R-SCE-741420-2)	0.527	2
UniProt:P02994	6	EEF1A1 [ficolin-1-rich granule lumen] (R-SCE-6801528) EEF1A1 [cytosol] (R-SCE-156905) EEF1A1 [extracellular region] (R-SCE-6806456) EEF1A1 [secretory granule lumen] (R-SCE-6801479) Me3K318-EEF1A1 [cytosol] (R-SCE-8932419) Me3K79-EEF1A1 [cytosol] (R-SCE-8932212)	0.527	2
UniProt:P05317	1	RPLP0 [cytosol] (R-SCE-72396)	0.527	2
UniProt:P16140	2	ATP6V1B1 [cytosol] (R-SCE-912604) ATP6V1B2 [cytosol] (R-SCE-912598)	0.527	2
UniProt:P00549	5	PKM [extracellular region] (R-SCE-6806491) PKM [secretory granule lumen] (R-SCE-6801401) PKM [ficolin-1-rich granule lumen] (R-SCE-6801387) PKLR-2 [cytosol] (R-SCE-211388) PKM-2 [cytosol] (R-SCE-450658)	0.527	2
UniProt:P07259	1	CAD [cytosol] (R-SCE-73452)	0.527	2
UniProt:P02309	14	AcK5,12-HIST1H4A [nucleoplasm] (R-SCE-212078) SUMO1-HIST1H4 [nucleoplasm] (R-SCE-4570518) AcK13-HIST1H4 [nucleoplasm] (R-SCE-4568744) AcK6-HIST1H4 [nucleoplasm] (R-SCE-4568748) AcK17-HIST1H4 [nucleoplasm] (R-SCE-427469) AcK9-HIST1H4 [nucleoplasm] (R-SCE-4568758) Me2aR4-HIST1H4 [nucleoplasm] (R-SCE-5229015) Me2sR4-HIST1H4 [nucleoplasm] (R-SCE-4754243) MeR4-HIST1H4 [nucleoplasm] (R-SCE-4754240) Me3K21-HIST1H4 [nucleoplasm] (R-SCE-5651656) AcK-HIST1H4 [nucleoplasm] (R-SCE-3451124) Me2K21-HIST1H4 [nucleoplasm] (R-SCE-5651652) HIST1H4 [nucleoplasm] (R-SCE-181902) MeK-HIST1H4A [nucleoplasm] (R-SCE-2172676)	0.527	2
UniProt:P05750 RPS3	3	RPS3 [cytosol] (R-SCE-9633213) RPS3 [nucleoplasm] (R-SCE-6798714) RPS3 [cytosol] (R-SCE-72369)	0.527	2
UniProt:P47035 NET1			0.527	2
UniProt:P25567 SRO9			0.527	2
UniProt:P05737 RPL7A	2	RPL7 [cytosol] (R-SCE-72486) RPL7A [cytosol] (R-SCE-9633181)	0.527	2
UniProt:Q03690 CLU			0.527	2
UniProt:P02294	15	Ub-HIST1H2BB [nucleoplasm] (R-SCE-6782554-2) Ub-HIST1H2BA [nucleoplasm] (R-SCE-6782561-2) AcK-HIST1H2BA [nucleoplasm] (R-SCE-4549263-2) AcK-HIST1H2BB [nucleoplasm] (R-SCE-4549272-2) AcK7-HIST1H2BA [nucleoplasm] (R-SCE-4568624-2) AcK14-HIST1H2BA [nucleoplasm] (R-SCE-4568615-2) AcK17-HIST1H2BA [nucleoplasm] (R-SCE-4568631-2) AcK22-HIST1H2BA [nucleoplasm] (R-SCE-4568647-2) AcK16-HIST2H2BE [nucleoplasm] (R-SCE-4568660-2) AcK21-HIST1H2BB [nucleoplasm] (R-SCE-4568632-2) AcK13-HIST1H2BB [nucleoplasm] (R-SCE-4568629-2) AcK16-HIST1H2BB [nucleoplasm] (R-SCE-4568639-2) AcK6-HIST1H2BB [nucleoplasm] (R-SCE-4568637-2) HIST1H2BA [nucleoplasm] (R-SCE-181916-2) HIST1H2BK [nucleoplasm] (R-SCE-181898-2)	0.527	2
UniProt:P38764	4	PSMD2 [extracellular region] (R-SCE-6806479) PSMD2 [secretory granule lumen] (R-SCE-6800919) PSMD2 [ficolin-1-rich granule lumen] (R-SCE-6800435) PSMD2 [cytosol] (R-SCE-68796)	0.527	2
UniProt:P11484	23	HSPA8 [nucleoplasm] (R-SCE-5082380-4) HSPA8 [cytosol] (R-SCE-264476-4) HSPA6 [ficolin-1-rich granule lumen] (R-SCE-6801512-4) HSPA1A [ficolin-1-rich granule lumen] (R-SCE-6801496-4) HSPA8 [ficolin-1-rich granule lumen] (R-SCE-6801494-4) HSPA1A [extracellular region] (R-SCE-6805872-4) HSPA6 [extracellular region] (R-SCE-6806500-4) HSPA8 [extracellular region] (R-SCE-6805936-4) HSPA8 [secretory granule lumen] (R-SCE-6801530-4) HSPA6 [secretory granule lumen] (R-SCE-6801472-4) HSPA2 [nucleoplasm] (R-SCE-912480-4) HSPA1L [nucleoplasm] (R-SCE-5082367-4) HSPA1A [nucleoplasm] (R-SCE-6792605-4) HSPA6 [nucleoplasm] (R-SCE-5252088-4) HSPA13 [nucleoplasm] (R-SCE-5252009-4) HSPA7 [nucleoplasm] (R-SCE-5252047-4) HSPA1L [cytosol] (R-SCE-3371410-4) HSPA2 [cytosol] (R-SCE-3371408-4) HSPA13 [cytosol] (R-SCE-5251981-4) HSPA6 [cytosol] (R-SCE-3371521-4) HSPA7 [cytosol] (R-SCE-5251954-4) HSPA1A [cytosol] (R-SCE-6792602-4) Me3K561-HSPA8 [nucleoplasm] (R-SCE-8932217-4)	0.527	2
UniProt:P10591	23	HSPA8 [nucleoplasm] (R-SCE-5082380-2) HSPA8 [cytosol] (R-SCE-264476-2) HSPA6 [ficolin-1-rich granule lumen] (R-SCE-6801512-2) HSPA1A [ficolin-1-rich granule lumen] (R-SCE-6801496-2) HSPA8 [ficolin-1-rich granule lumen] (R-SCE-6801494-2) HSPA1A [extracellular region] (R-SCE-6805872-2) HSPA6 [extracellular region] (R-SCE-6806500-2) HSPA8 [extracellular region] (R-SCE-6805936-2) HSPA8 [secretory granule lumen] (R-SCE-6801530-2) HSPA6 [secretory granule lumen] (R-SCE-6801472-2) HSPA2 [nucleoplasm] (R-SCE-912480-2) HSPA1L [nucleoplasm] (R-SCE-5082367-2) HSPA1A [nucleoplasm] (R-SCE-6792605-2) HSPA6 [nucleoplasm] (R-SCE-5252088-2) HSPA13 [nucleoplasm] (R-SCE-5252009-2) HSPA7 [nucleoplasm] (R-SCE-5252047-2) HSPA1L [cytosol] (R-SCE-3371410-2) HSPA2 [cytosol] (R-SCE-3371408-2) HSPA13 [cytosol] (R-SCE-5251981-2) HSPA6 [cytosol] (R-SCE-3371521-2) HSPA7 [cytosol] (R-SCE-5251954-2) HSPA1A [cytosol] (R-SCE-6792602-2) Me3K561-HSPA8 [nucleoplasm] (R-SCE-8932217-2)	0.527	2
UniProt:P21954	6	IDH1 [ficolin-1-rich granule lumen] (R-SCE-6800977) IDH1 [secretory granule lumen] (R-SCE-6800980) IDH1 [extracellular region] (R-SCE-6806433) IDH1 [tertiary granule lumen] (R-SCE-6800163) IDH1 [peroxisomal matrix] (R-SCE-389546) IDH1 [cytosol] (R-SCE-389549)	0.527	2
UniProt:P02557	24	Polyglycyl-TUBB3 [cytosol] (R-SCE-8867372) Polyglycyl-TUBB1 [cytosol] (R-SCE-8867450) Polyglycyl-TUBB2A [cytosol] (R-SCE-8867466) Polyglycyl-TUBB6 [cytosol] (R-SCE-8867396) Polyglycyl-TUBB4A [cytosol] (R-SCE-8867397) Polyglutamyl-TUBB3 [cytosol] (R-SCE-8867464) Polyglutamyl-TUBB4A [cytosol] (R-SCE-8867425) Polyglutamyl-TUBB2A [cytosol] (R-SCE-8867392) Polyglutamyl-TUBB1 [cytosol] (R-SCE-8867413) Polyglutamyl-TUBB6 [cytosol] (R-SCE-8867399) TUBB4A [axonemal microtubule] (R-SCE-5610435) TUBB4B [axonemal microtubule] (R-SCE-5610441) TUBB6 [axonemal microtubule] (R-SCE-5610438) TUBB3 [axonemal microtubule] (R-SCE-5610436) TUBB1 [axonemal microtubule] (R-SCE-5610437) TUBB4B [extracellular region] (R-SCE-6806178) TUBB [azurophil granule lumen] (R-SCE-6799370) TUBB4B [azurophil granule lumen] (R-SCE-6799347) TUBB [extracellular region] (R-SCE-380317) TUBB4A [cytosol] (R-SCE-190588) TUBB3 [cytosol] (R-SCE-190532) TUBB1 [cytosol] (R-SCE-191703) TUBB4B [cytosol] (R-SCE-191702) TUBB6 [cytosol] (R-SCE-191698)	0.527	2
UniProt:Q12000 TMA46			0.527	2
UniProt:P50095	5	IMPDH1 [secretory granule lumen] (R-SCE-6800971) IMPDH1 [azurophil granule lumen] (R-SCE-6799173) IMPDH1 [extracellular region] (R-SCE-6806182) IMPDH1 [ficolin-1-rich granule lumen] (R-SCE-6800927) IMPDH1 [cytosol] (R-SCE-57348)	0.527	2
UniProt:P26321 RPL5	1	RPL5 [cytosol] (R-SCE-9633136)	0.527	2
UniProt:P04912 H2A2			0.527	2
UniProt:Q00684	1	CDC14A [cytosol] (R-SCE-174094)	0.527	2
UniProt:Q01477	3	USP37 [nucleoplasm] (R-SCE-5697000) USP10 [nucleoplasm] (R-SCE-3222218) USP10 [cytosol] (R-SCE-6782974)	0.527	2
UniProt:P38219	2	OLA1 [platelet alpha granule lumen] (R-SCE-8862978) OLA1 [extracellular region] (R-SCE-8863004)	0.527	2
UniProt:P12385 SUP45	3	Me-Q185-ETF1 [cytosol] (R-SCE-6800157) Erf-1 [cytosol] (R-SCE-141665) ETF1 [cytosol] (R-SCE-54433)	0.527	2