Reactome | ERN1 [endoplasmic reticulum membrane]

ERN1 [endoplasmic reticulum membrane]

Stable Identifier

R-SCE-381076

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

endoplasmic reticulum membrane

Synonyms

P32361

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P32361 IRE1

Gene Names

IRE1, ERN1, YHR079C

Chain

signal peptide:1-18, chain:19-1115

Reference Genes

BioGPS Gene:856478 IRE1

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YHR079C IRE1

Monarch:856478 IRE1

NCBI Gene:856478 IRE1

Reference Transcript

RefSeq:NM_001179209.1 IRE1

Other Identifiers

1769634_at

4459_at

856478

GO:0000042

GO:0000166

GO:0003674

GO:0003824

GO:0004518

GO:0004521

GO:0004540

GO:0004672

GO:0004674

GO:0005515

GO:0005524

GO:0005575

GO:0005634

GO:0005737

GO:0005783

GO:0005789

GO:0005975

GO:0006020

GO:0006351

GO:0006355

GO:0006397

GO:0006468

GO:0006986

GO:0008150

GO:0008152

GO:0012505

GO:0016020

GO:0016301

GO:0016310

GO:0016740

GO:0016787

GO:0023052

GO:0030176

GO:0030968

GO:0031505

GO:0034067

GO:0034976

GO:0036290

GO:0036498

GO:0042221

GO:0042802

GO:0042803

GO:0043167

GO:0046872

GO:0051082

GO:0051260

GO:0071554

GO:0106310

GO:1990332

GO:1990604

Participates

as an input of

IRE1 binds IRE1 forming dimer (Saccharomyces cerevisiae)

as a component of

Other forms of this molecule

p-3S,T844-IRE1 [endoplasmic reticulum membrane]

phospho-p-S724-ERN1 [endoplasmic reticulum membrane]

Inferred From

ERN1 [endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

NP_011946.1

PRO

P32361

PDB

3SDJ, 2RIO, 3LJ2, 2BE1, 3SDM, 3LJ0, 3LJ1, 3FBV

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P32361 IRE1	3	p-3S,T844-IRE1 [endoplasmic reticulum membrane] (R-SCE-535555) phospho-p-S724-ERN1 [endoplasmic reticulum membrane] (R-SCE-381029) ERN1 [endoplasmic reticulum membrane] (R-SCE-381076)	0.782	5
ChEBI:16761 ADP			0.558	2
UniProt:Q05924 DCR2			0.544	2
UniProt:P11484	17	HSPA6 [ficolin-1-rich granule lumen] (R-SCE-6801512-4) HSPA1A [ficolin-1-rich granule lumen] (R-SCE-6801496-4) HSPA1A [extracellular region] (R-SCE-6805872-4) HSPA6 [extracellular region] (R-SCE-6806500-4) HSPA6 [secretory granule lumen] (R-SCE-6801472-4) HSPA1L [cytosol] (R-SCE-3371410-4) HSPA2 [cytosol] (R-SCE-3371408-4) HSPA1A [cytosol] (R-SCE-6792602-4) HSPA1A [nucleoplasm] (R-SCE-6792605-4) HSPA2 [nucleoplasm] (R-SCE-912480-4) HSPA1L [nucleoplasm] (R-SCE-5082367-4) HSPA14 [nucleoplasm] (R-SCE-5252082-4) HSPA6 [nucleoplasm] (R-SCE-5252088-4) HSPA13 [nucleoplasm] (R-SCE-5252009-4) HSPA14 [cytosol] (R-SCE-5251948-4) HSPA13 [cytosol] (R-SCE-5251981-4) HSPA6 [cytosol] (R-SCE-3371521-4)	0.527	2
UniProt:P40150	17	HSPA6 [cytosol] (R-SCE-3371521-6) HSPA13 [cytosol] (R-SCE-5251981-6) HSPA14 [cytosol] (R-SCE-5251948-6) HSPA13 [nucleoplasm] (R-SCE-5252009-6) HSPA6 [nucleoplasm] (R-SCE-5252088-6) HSPA14 [nucleoplasm] (R-SCE-5252082-6) HSPA1L [nucleoplasm] (R-SCE-5082367-6) HSPA2 [nucleoplasm] (R-SCE-912480-6) HSPA1A [nucleoplasm] (R-SCE-6792605-6) HSPA1A [cytosol] (R-SCE-6792602-6) HSPA2 [cytosol] (R-SCE-3371408-6) HSPA1L [cytosol] (R-SCE-3371410-6) HSPA6 [secretory granule lumen] (R-SCE-6801472-6) HSPA6 [extracellular region] (R-SCE-6806500-6) HSPA1A [extracellular region] (R-SCE-6805872-6) HSPA1A [ficolin-1-rich granule lumen] (R-SCE-6801496-6) HSPA6 [ficolin-1-rich granule lumen] (R-SCE-6801512-6)	0.527	2

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