Reactome | DOA1 [cytosol]

DOA1 [cytosol]

Stable Identifier

R-SCE-391304

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

FBXW7, P36037

Locations in the PathwayBrowser

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Immune System (Saccharomyces cerevisiae)

- Adaptive Immune System (Saccharomyces cerevisiae)
  - Class I MHC mediated antigen processing & presentation (Saccharomyces cerevisiae)
    - Antigen processing: Ubiquitination & Proteasome degradation (Saccharomyces cerevisiae)
      - Release of E3 from polyubiquitinated substrate (Saccharomyces cerevisiae)
        
        E3 ligases in proteasomal degradation [cytosol] (Saccharomyces cerevisiae)
        
        SCF E3 ubiquitin ligase [cytosol] (Saccharomyces cerevisiae)
        
        F-box protein [cytosol] (Saccharomyces cerevisiae)
        
        DOA1 [cytosol] (Saccharomyces cerevisiae)
        
        E3:K48-polyubiquitinated substrate [cytosol] (Saccharomyces cerevisiae)
        
        E3 ligases in proteasomal degradation [cytosol] (Saccharomyces cerevisiae)
        
        SCF E3 ubiquitin ligase [cytosol] (Saccharomyces cerevisiae)
        
        F-box protein [cytosol] (Saccharomyces cerevisiae)
        
        DOA1 [cytosol] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P36037

Gene Names

DOA1

Reference Genes

BioGPS Gene:853667 DOA1

ENSEMBL:YKL213C

KEGG Gene (Saccharomyces cerevisiae (strain YJM789)):YKL213C DOA1

Monarch:853667 DOA1

NCBI Gene:853667 DOA1

SGD:YKL213C

Reference Transcript

RefSeq:NM_001179778.1 DOA1

Other Identifiers

10799_at

1777317_at

853667

GO:0003674

GO:0005515

GO:0005575

GO:0005634

GO:0005737

GO:0005739

GO:0005740

GO:0005741

GO:0005768

GO:0006281

GO:0006303

GO:0006974

GO:0008150

GO:0010008

GO:0010992

GO:0012505

GO:0016020

GO:0031410

GO:0032182

GO:0032473

GO:0034517

GO:0043130

GO:0043161

GO:0044877

GO:0051603

GO:0072671

GO:0140036

Participates

as a member of

F-box protein [cytosol] (Saccharomyces cerevisiae)

Inferred From

FBXW7 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_012709.1

PRO

P36037

PDB

3ODT, 3PST, 3GAE, 3L3F, 3PSP

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P25694	7	VCP [cytosol] (R-SCE-1181251) VCP [ficolin-1-rich granule lumen] (R-SCE-6800425) VCP [extracellular region] (R-SCE-6806191) VCP [secretory granule lumen] (R-SCE-6801039) VCP [azurophil granule lumen] (R-SCE-6800438) VCP [nucleoplasm] (R-SCE-5643745) Me3K315-VCP [cytosol] (R-SCE-8932209)	0.84	26

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