Reactome | HTB2 [nucleoplasm]

HTB2 [nucleoplasm]

Stable Identifier

R-SCE-4568624-2

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

AcK7-HIST1H2BA, P02294

Locations in the PathwayBrowser

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Chromatin organization (Saccharomyces cerevisiae)

- Chromatin modifying enzymes (Saccharomyces cerevisiae)
  - HDACs deacetylate histones (Saccharomyces cerevisiae)
    - HDAC10 deacetylates histone (Saccharomyces cerevisiae)
      - Acetylated core histone octamer [nucleoplasm] (Saccharomyces cerevisiae)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Saccharomyces cerevisiae)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Saccharomyces cerevisiae)
        
        AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Saccharomyces cerevisiae)
        
        AcK(7,14,17,22)-HIST1H2BA [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of AcK7-HIST1H2BA [nucleoplasm] (Saccharomyces cerevisiae)
        
        HTB2 [nucleoplasm] (Saccharomyces cerevisiae)
    - HDAC1:2-containing complex deacetylate histones (Saccharomyces cerevisiae)
      - Acetylated core histone octamer [nucleoplasm] (Saccharomyces cerevisiae)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Saccharomyces cerevisiae)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Saccharomyces cerevisiae)
        
        AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Saccharomyces cerevisiae)
        
        AcK(7,14,17,22)-HIST1H2BA [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of AcK7-HIST1H2BA [nucleoplasm] (Saccharomyces cerevisiae)
        
        HTB2 [nucleoplasm] (Saccharomyces cerevisiae)
    - HDAC3 containing complexes deacetylate histone (Saccharomyces cerevisiae)
      - Acetylated core histone octamer [nucleoplasm] (Saccharomyces cerevisiae)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Saccharomyces cerevisiae)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Saccharomyces cerevisiae)
        
        AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Saccharomyces cerevisiae)
        
        AcK(7,14,17,22)-HIST1H2BA [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of AcK7-HIST1H2BA [nucleoplasm] (Saccharomyces cerevisiae)
        
        HTB2 [nucleoplasm] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P02294

Gene Names

HTB2

Reference Genes

BioGPS Gene:852284 HTB2

ENSEMBL:YBL002W

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YBL002W HTB2

Monarch:852284 HTB2

NCBI Gene:852284 HTB2

SGD:YBL002W

Reference Transcript

RefSeq:NM_001178242.1 HTB2

Other Identifiers

1777846_at

7359_at

852284

GO:0000786

GO:0000788

GO:0003674

GO:0003677

GO:0005575

GO:0005634

GO:0005694

GO:0006325

GO:0006333

GO:0008150

GO:0031298

GO:0046982

Participant Of

hasMember

Homologues of AcK7-HIST1H2BA [nucleoplasm]

Other forms of this molecule

HTB2 [nucleoplasm]

Inferred From

AcK7-HIST1H2BA [nucleoplasm] (Homo sapiens)

Modified Residues

Name

N6-acetyl-L-lysine at 7 (in Homo sapiens)

Coordinate

PsiMod Name

N6-acetyl-L-lysine [MOD:00064]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.

Cross References

RefSeq

NP_009553.1

PRO

P02294

PDB

2FSB, 6QLD, 1ID3, 4JJN

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P02309	14	HHF2 [nucleoplasm] (R-SCE-212078) HHF2 [nucleoplasm] (R-SCE-4570518) HHF2 [nucleoplasm] (R-SCE-4568744) HHF2 [nucleoplasm] (R-SCE-4568748) HHF2 [nucleoplasm] (R-SCE-427469) HHF2 [nucleoplasm] (R-SCE-4568758) HHF2 [nucleoplasm] (R-SCE-5229015) HHF2 [nucleoplasm] (R-SCE-4754243) HHF2 [nucleoplasm] (R-SCE-4754240) HHF2 [nucleoplasm] (R-SCE-5651656) HHF2 [nucleoplasm] (R-SCE-3451124) HHF2 [nucleoplasm] (R-SCE-2172676) HHF2 [nucleoplasm] (R-SCE-181902) HHF2 [nucleoplasm] (R-SCE-5651652)	0.564	8
UniProt:P32558	1	SPT16 [nucleoplasm] (R-SCE-112415)	0.564	14