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TOP2 [nucleoplasm]
Stable Identifier
R-SCE-4641367
Type
Protein [EntityWithAccessionedSequence]
Species
Saccharomyces cerevisiae
Compartment
nucleoplasm
Synonyms
SUMO1-K-TOP2A, P06786
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Saccharomyces cerevisiae)
Post-translational protein modification (Saccharomyces cerevisiae)
SUMOylation (Saccharomyces cerevisiae)
SUMO E3 ligases SUMOylate target proteins (Saccharomyces cerevisiae)
SUMOylation of DNA replication proteins (Saccharomyces cerevisiae)
SUMOylation of TOP2A with SUMO1 (Saccharomyces cerevisiae)
SUMO1:TOP2A [nucleoplasm] (Saccharomyces cerevisiae)
TOP2 [nucleoplasm] (Saccharomyces cerevisiae)
External Reference Information
External Reference
UniProt:P06786
Gene Names
TOP2
Reference Genes
BioGPS Gene:855636 TOP2
ENSEMBL:YNL088W
KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YNL088W TOP2
Monarch:855636 TOP2
NCBI Gene:855636 TOP2
SGD:YNL088W
Reference Transcript
RefSeq:NM_001182926.3 TOP2
Other Identifiers
1779900_at
855636
8944_at
GO:0000019
GO:0000278
GO:0000712
GO:0000795
GO:0000819
GO:0003674
GO:0003677
GO:0003918
GO:0005524
GO:0005575
GO:0005634
GO:0005694
GO:0006260
GO:0006265
GO:0006271
GO:0006310
GO:0006325
GO:0006333
GO:0007059
GO:0007131
GO:0008150
GO:0016787
GO:0016853
GO:0016887
GO:0031055
GO:0042802
GO:0043167
GO:0044774
GO:0046872
GO:0048285
GO:0051052
GO:0051321
GO:0051726
GO:0097046
GO:0097047
Participant Of
hasComponent
SUMO1:TOP2A [nucleoplasm]
Other forms of this molecule
TOP2 [nucleoplasm]
TOP2 [nucleoplasm]
TOP2 [nucleoplasm]
Inferred From
SUMO1-K-TOP2A [nucleoplasm] (Homo sapiens)
Modified Residues
Name
UniProt:P06786 glycyl group sumoylated lysine
PsiMod Name
sumoylated lysine
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Cross References
RefSeq
NP_014311.3
PRO
P06786
PDB
3L4J
,
1BJT
,
1QZR
,
1BGW
,
1PVG
,
3L4K
,
4GFH
,
2RGR
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P06786
4
TOP2 [nucleoplasm]
(R-SCE-4641359)
TOP2 [nucleoplasm]
(R-SCE-4641297)
TOP2 [nucleoplasm]
(R-SCE-4641367)
TOP2 [nucleoplasm]
(R-SCE-1362276)
0.825
5
UniProt:Q12159
2
YRA1 [cytosol]
(R-SCE-158482)
YRA1 [nucleoplasm]
(R-SCE-156649)
0.564
6
UniProt:P10591
23
SSA1 [nucleoplasm]
(R-SCE-5082380-2)
SSA1 [cytosol]
(R-SCE-264476-2)
SSA1 [secretory granule lumen]
(R-SCE-6801530-2)
SSA1 [secretory granule lumen]
(R-SCE-6801472-2)
SSA1 [extracellular region]
(R-SCE-6806500-2)
SSA1 [extracellular region]
(R-SCE-6805936-2)
SSA1 [ficolin-1-rich granule lumen]
(R-SCE-6801512-2)
SSA1 [ficolin-1-rich granule lumen]
(R-SCE-6801496-2)
SSA1 [ficolin-1-rich granule lumen]
(R-SCE-6801494-2)
SSA1 [extracellular region]
(R-SCE-6805872-2)
SSA1 [nucleoplasm]
(R-SCE-6792605-2)
SSA1 [nucleoplasm]
(R-SCE-912480-2)
SSA1 [nucleoplasm]
(R-SCE-5082367-2)
SSA1 [nucleoplasm]
(R-SCE-5252082-2)
SSA1 [nucleoplasm]
(R-SCE-5252088-2)
SSA1 [nucleoplasm]
(R-SCE-5252047-2)
SSA1 [cytosol]
(R-SCE-3371410-2)
SSA1 [cytosol]
(R-SCE-5251948-2)
SSA1 [cytosol]
(R-SCE-3371408-2)
SSA1 [cytosol]
(R-SCE-3371521-2)
SSA1 [cytosol]
(R-SCE-5251954-2)
SSA1 [cytosol]
(R-SCE-6792602-2)
SSA1 [nucleoplasm]
(R-SCE-8932217-2)
0.527
2
UniProt:P11484 SSB1
0.527
3
UniProt:P24583
37
PKC1 [nucleoplasm]
(R-SCE-450530)
PKC1 [nucleoplasm]
(R-SCE-450606)
PKC1 [cytosol]
(R-SCE-58208)
PKC1 [extracellular region]
(R-SCE-6806199)
PKC1 [extracellular region]
(R-SCE-6806226)
PKC1 [azurophil granule lumen]
(R-SCE-6799219)
PKC1 [azurophil granule lumen]
(R-SCE-6799221)
phospho-PKC1 [cytosol]
(R-SCE-9632824)
PKC1 [cytosol]
(R-SCE-212551)
PKC1 [cytosol]
(R-SCE-212547)
PKC1 [cytosol]
(R-SCE-212526)
PKC1 [cytosol]
(R-SCE-212514)
PKC1 [cytosol]
(R-SCE-58202)
PKC1 [plasma membrane]
(R-SCE-156467)
PKC1 [plasma membrane]
(R-SCE-156469)
PKC1 [cytosol]
(R-SCE-58204)
phospho-PKC1 [plasma membrane]
(R-SCE-198260)
PKC1 [cytosol]
(R-SCE-58196)
phospho-PKC1 [nucleoplasm]
(R-SCE-5223294)
phospho-PKC1 [nucleoplasm]
(R-SCE-5223292)
phospho-PKC1 [cytosol]
(R-SCE-5218731)
phospho-PKC1 [cytosol]
(R-SCE-5218746)
phospho-PKC1 [cytosol]
(R-SCE-5218728)
phospho-PKC1 [cytosol]
(R-SCE-437181)
phospho-PKC1 [cytosol]
(R-SCE-5218734)
phospho-PKC1 [cytosol]
(R-SCE-4332337)
phospho-PKC1 [cytosol]
(R-SCE-5218698)
phospho-PKC1 [cytosol]
(R-SCE-5218706)
PKC1 [cytosol]
(R-SCE-58198)
PKC1 [cytosol]
(R-SCE-58200)
PKC1 [cytosol]
(R-SCE-58218)
PKC1 [plasma membrane]
(R-SCE-202346)
phospho-PKC1 [plasma membrane]
(R-SCE-202395)
PKC1 [cytosol]
(R-SCE-58216)
phospho-PKC1 [plasma membrane]
(R-SCE-202152)
phospho-PKC1 [plasma membrane]
(R-SCE-2685606)
phospho-PKC1 [plasma membrane]
(R-SCE-198294)
0.508
2
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