Reactome | NCBP2 [nucleoplasm]

NCBP2 [nucleoplasm]

Stable Identifier

R-SCE-51463

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

Q08920

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Saccharomyces cerevisiae)

- RNA Polymerase II Transcription (Saccharomyces cerevisiae)
  - RNA Polymerase II Pre-transcription Events (Saccharomyces cerevisiae)
    - Abortive termination of early transcription elongation by DSIF:NELF (Saccharomyces cerevisiae)
      - DSIF:NELF:early elongation complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        RNA Pol II (hypophosphorylated) complex bound to DSIF protein [nucleoplasm] (Saccharomyces cerevisiae)
        
        RNA Pol II (hypophosphorylated):capped pre-mRNA complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        Cap Binding Complex (CBC) [nucleoplasm] (Saccharomyces cerevisiae)
        
        NCBP2 [nucleoplasm] (Saccharomyces cerevisiae)
  - RNA Polymerase II Transcription Elongation (Saccharomyces cerevisiae)
    - Formation of the Early Elongation Complex (Saccharomyces cerevisiae)
      - DSIF complex binds to RNA Pol II (hypophosphorylated) (Saccharomyces cerevisiae)
        
        RNA Pol II (hypophosphorylated) complex bound to DSIF protein [nucleoplasm] (Saccharomyces cerevisiae)
        
        RNA Pol II (hypophosphorylated):capped pre-mRNA complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        Cap Binding Complex (CBC) [nucleoplasm] (Saccharomyces cerevisiae)
        
        NCBP2 [nucleoplasm] (Saccharomyces cerevisiae)
        
        RNA Pol II (hypophosphorylated):capped pre-mRNA complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        Cap Binding Complex (CBC) [nucleoplasm] (Saccharomyces cerevisiae)
        
        NCBP2 [nucleoplasm] (Saccharomyces cerevisiae)
      - Hypophosphorylation of RNA Pol II CTD by FCP1P protein (Saccharomyces cerevisiae)
        
        RNA Pol II (hypophosphorylated):capped pre-mRNA complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        Cap Binding Complex (CBC) [nucleoplasm] (Saccharomyces cerevisiae)
        
        NCBP2 [nucleoplasm] (Saccharomyces cerevisiae)
        
        capped pre-mRNA:CBC:RNA Pol II (phosphorylated) complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        Cap Binding Complex (CBC) [nucleoplasm] (Saccharomyces cerevisiae)
        
        NCBP2 [nucleoplasm] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:Q08920

Reference Genes

BioGPS Gene:855925

dbSNP Gene:855925

ENSEMBL:YPL178W

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YPL178W

Monarch:855925

NCBI Gene:855925

SGD:YPL178W

Reference Transcript

RefSeq:NM_001183992.1

Other Identifiers

1770708_at

4932.YPL178W

7937_at

AAT92968.1

CAA97885.1

DAA11256.1

EntrezGene:855925

EntrezGene:CBC2

GO:0000184

GO:0000243

GO:0000339

GO:0000398

GO:0003674

GO:0003676

GO:0003723

GO:0005575

GO:0005634

GO:0005737

GO:0005846

GO:0006397

GO:0006401

GO:0008150

GO:0008380

GO:0015931

GO:0045292

GO:0048471

GO:0051028

IPR000504

IPR012677

IPR027157

IPR034148

IPR035979

NM_001183992.1

NP_015147.1

PF00076

SM00360

U39665

UPI00000530E9

YPL178W

YPL178W_mRNA

Participant Of

hasComponent

input

Formation of cap binding complex (CBC)

Other forms of this molecule

NCBP2 [cytosol]

Inferred From

NCBP2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_015147.1

PRO

Q08920

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P34160	2	NCBP1 [nucleoplasm] (R-SCE-51469) NCBP1 [cytosol] (R-SCE-162459)	0.818	25
UniProt:Q02821	2	KPNA2 [cytosol] (R-SCE-205976) KPNA1 [cytosol] (R-SCE-180612)	0.771	11
UniProt:Q06142	4	KPNB1 [extracellular region] (R-SCE-6806306) KPNB1 [specific granule lumen] (R-SCE-6799646) KPNB1 [ficolin-1-rich granule lumen] (R-SCE-6800978) KPNB1 [cytosol] (R-SCE-180733)	0.669	6
UniProt:P53617	2	SFPQ [nucleoplasm] (R-SCE-3900138) phospho-p-Y-SFPQ [nucleoplasm] (R-SCE-8849461)	0.643	3
UniProt:P38996	2	HNRNPC [nucleoplasm] (R-SCE-71933) SUMO1-K250-HNRNPC [nucleoplasm] (R-SCE-4570543)	0.527	3
UniProt:Q03735 NAB6			0.527	2
UniProt:P10591	23	HSPA6 [ficolin-1-rich granule lumen] (R-SCE-6801512-2) HSPA8 [cytosol] (R-SCE-264476-2) HSPA1A [ficolin-1-rich granule lumen] (R-SCE-6801496-2) HSPA8 [ficolin-1-rich granule lumen] (R-SCE-6801494-2) HSPA1A [extracellular region] (R-SCE-6805872-2) HSPA6 [extracellular region] (R-SCE-6806500-2) HSPA8 [extracellular region] (R-SCE-6805936-2) HSPA8 [secretory granule lumen] (R-SCE-6801530-2) HSPA6 [secretory granule lumen] (R-SCE-6801472-2) HSPA8 [nucleoplasm] (R-SCE-5082380-2) HSPA2 [nucleoplasm] (R-SCE-912480-2) HSPA1L [nucleoplasm] (R-SCE-5082367-2) HSPA1A [nucleoplasm] (R-SCE-6792605-2) HSPA6 [nucleoplasm] (R-SCE-5252088-2) HSPA13 [nucleoplasm] (R-SCE-5252009-2) HSPA7 [nucleoplasm] (R-SCE-5252047-2) HSPA1L [cytosol] (R-SCE-3371410-2) HSPA2 [cytosol] (R-SCE-3371408-2) HSPA13 [cytosol] (R-SCE-5251981-2) HSPA6 [cytosol] (R-SCE-3371521-2) HSPA7 [cytosol] (R-SCE-5251954-2) HSPA1A [cytosol] (R-SCE-6792602-2) Me3K561-HSPA8 [nucleoplasm] (R-SCE-8932217-2)	0.527	2
UniProt:Q07508 LUC7			0.527	2
UniProt:Q00539 NAM8			0.527	3
UniProt:P11484	23	HSPA6 [ficolin-1-rich granule lumen] (R-SCE-6801512-4) HSPA8 [cytosol] (R-SCE-264476-4) HSPA1A [ficolin-1-rich granule lumen] (R-SCE-6801496-4) HSPA8 [ficolin-1-rich granule lumen] (R-SCE-6801494-4) HSPA1A [extracellular region] (R-SCE-6805872-4) HSPA6 [extracellular region] (R-SCE-6806500-4) HSPA8 [extracellular region] (R-SCE-6805936-4) HSPA8 [secretory granule lumen] (R-SCE-6801530-4) HSPA6 [secretory granule lumen] (R-SCE-6801472-4) HSPA8 [nucleoplasm] (R-SCE-5082380-4) HSPA2 [nucleoplasm] (R-SCE-912480-4) HSPA1L [nucleoplasm] (R-SCE-5082367-4) HSPA1A [nucleoplasm] (R-SCE-6792605-4) HSPA6 [nucleoplasm] (R-SCE-5252088-4) HSPA13 [nucleoplasm] (R-SCE-5252009-4) HSPA7 [nucleoplasm] (R-SCE-5252047-4) HSPA1L [cytosol] (R-SCE-3371410-4) HSPA2 [cytosol] (R-SCE-3371408-4) HSPA13 [cytosol] (R-SCE-5251981-4) HSPA6 [cytosol] (R-SCE-3371521-4) HSPA7 [cytosol] (R-SCE-5251954-4) HSPA1A [cytosol] (R-SCE-6792602-4) Me3K561-HSPA8 [nucleoplasm] (R-SCE-8932217-4)	0.527	2
UniProt:Q06217	1	SNRPD2 [cytosol] (R-SCE-191810)	0.527	2
UniProt:Q01560 NOP3			0.527	2
UniProt:Q03782 SNU56			0.527	2
UniProt:P39936 IF4F2			0.527	2
UniProt:P53207 SNU71			0.527	3
UniProt:Q04693 RSE1			0.527	2
UniProt:Q00916 RU17			0.527	2