Phosphorylated Ire1 Dimer Binds ADP

Stable Identifier
R-SCE-535524
Type
Reaction [binding]
Species
Saccharomyces cerevisiae
Compartment
endoplasmic reticulum membrane, cytosol
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Phosphorylated Ire1 Dimer Binds ADP

Ire1 phosphorylated in the activation domain preferentially binds ADP (rather than ATP).

Literature References
PubMed ID Title Journal Year
18191223 Structure of the dual enzyme Ire1 reveals the basis for catalysis and regulation in nonconventional RNA splicing

Lee, KP, Dey, M, Neculai, D, Cao, C, Dever, TE, Sicheri, F

Cell 2008
Participants
Input
Output
Orthologous Events
Phosphorylated IRE1 dimer binds ADP (Homo sapiens)
Authored
May, B  (2010-03-03)
Reviewed
May, B  (2010-03-03)
Created
May, B  (2010-03-04)
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