Reactome | ATG8 [autophagosome membrane]

ATG8 [autophagosome membrane]

Stable Identifier

R-SCE-5683640

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

autophagosome membrane

Synonyms

MAP1LC3A, P38182

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P38182

Gene Names

ATG8

Reference Genes

BioGPS Gene:852200 ATG8

ENSEMBL:YBL078C

KEGG Gene (Saccharomyces cerevisiae):YBL078C ATG8

Monarch:852200 ATG8

NCBI Gene:852200 ATG8

SGD:YBL078C

Reference Transcript

RefSeq:NM_001178318.1 ATG8

Other Identifiers

1772778_at

7464_at

852200

GO:0000045

GO:0000329

GO:0000407

GO:0000421

GO:0000422

GO:0003674

GO:0005575

GO:0005737

GO:0005773

GO:0005776

GO:0005829

GO:0006605

GO:0006888

GO:0006914

GO:0006995

GO:0007005

GO:0007033

GO:0008150

GO:0008289

GO:0008429

GO:0015031

GO:0016020

GO:0016241

GO:0019898

GO:0031386

GO:0031410

GO:0032258

GO:0033110

GO:0034497

GO:0034629

GO:0034727

GO:0042594

GO:0043167

GO:0044805

GO:0048193

GO:0061025

GO:0061709

GO:0070925

GO:0071211

GO:0120095

Participant Of

hasComponent

LC3:PE [autophagosome membrane]

Other forms of this molecule

ATG8 [cytosol]

ATG8 [autophagosome membrane]

Inferred From

MAP1LC3A [autophagosome membrane] (Homo sapiens)

LC3 family [autophagosome membrane] (Homo sapiens)

Cross References

RefSeq

NP_009475.1

PRO

P38182

PDB

3VH3, 6AAG, 5YEC, 3RUI, 2KQ7, 3VXW, 2LI5, 2KWC, 2ZPN, 3VH4

Interactors (18)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P38862	5	ATG7 [extracellular region] (R-SCE-6806451) ATG7 [secretory granule lumen] (R-SCE-6801316) ATG7 [ficolin-1-rich granule lumen] (R-SCE-6801293) ATG7 [cytosol] (R-SCE-5683584) ATG7 [cytosol] (R-SCE-947867)	0.942	12
UniProt:P40344	2	ATG3 [cytosol] (R-SCE-5683569) ATG3 [cytosol] (R-SCE-5671860)	0.894	9
UniProt:Q12292 ATG34			0.743	4
UniProt:O60238 BNIP3L	1	BNIP3L [mitochondrial outer membrane] (R-HSA-6798001)	0.666	4
UniProt:P35193 ATG19			0.65	5
UniProt:P53867	4	ATG4 [cytosol] (R-SCE-5671857) ATG4 [cytosol] (R-SCE-5671858) ATG4 [cytosol] (R-SCE-5671859) ATG4 [cytosol] (R-SCE-5671863)	0.635	3
UniProt:Q14596 NBR1	2	NBR1 [cytosol] (R-HSA-9665180) NBR1 [peroxisomal membrane] (R-HSA-9665177)	0.635	7
UniProt:Q08412	3	CUE5 [extracellular region] (R-SCE-6800448) CUE5 [azurophil granule lumen] (R-SCE-6799709) CUE5 [specific granule lumen] (R-SCE-6799719)	0.591	4
UniProt:Q96GX9 APIP	1	APIP [cytosol] (R-HSA-1237171)	0.556	3
UniProt:Q12983 BNIP3			0.556	3
UniProt:Q92609 TBCD5			0.556	3
UniProt:O43379 WDR62			0.556	3
UniProt:Q9UH92-3 MLX			0.556	3
UniProt:P53104	7	phospho-ATG1 [cytosol] (R-SCE-5672131) ATG1 [recycling endosome] (R-SCE-8854761) phospho-ATG1 [cytosol] (R-SCE-5673747) phospho-ATG1 [cytosol] (R-SCE-5675858) phospho-ATG1 [endoplasmic reticulum membrane] (R-SCE-8948047) ATG1 [mitochondrial outer membrane] (R-SCE-8948145) ATG1 [cytosol] (R-SCE-1632847)	0.544	3
UniProt:Q99325 ATG40			0.508	3
UniProt:Q06159 ATG39			0.508	3
UniProt:Q13501 SQSTM1	2	SQSTM1 [cytosol] (R-HSA-193937) SQSTM1 [nucleoplasm] (R-HSA-210961)	0.508	3
UniProt:P22804	4	BET1 [transport vesicle] (R-SCE-6808719) BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-SCE-5688142) BET1 [Golgi membrane] (R-SCE-6807743) BET1 [Golgi membrane] (R-SCE-6807744)	0.499	2

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