Reactome | phospho-SEC23 [cytosol]

phospho-SEC23 [cytosol]

Stable Identifier

R-SCE-5685740

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

p-S742,T747 SEC23A, P15303

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Saccharomyces cerevisiae)

- Post-translational protein modification (Saccharomyces cerevisiae)
  - Asparagine N-linked glycosylation (Saccharomyces cerevisiae)
    - Transport to the Golgi and subsequent modification (Saccharomyces cerevisiae)
      - ER to Golgi Anterograde Transport (Saccharomyces cerevisiae)
        
        COPII-mediated vesicle transport (Saccharomyces cerevisiae)
        
        CSNK1D phosphorylates SEC23 (Saccharomyces cerevisiae)
        
        phospho-SEC23 [cytosol] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P15303

Gene Names

SEC23

Reference Genes

BioGPS Gene:856311 SEC23

ENSEMBL:YPR181C

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YPR181C SEC23

Monarch:856311 SEC23

NCBI Gene:856311 SEC23

SGD:YPR181C

Reference Transcript

RefSeq:NM_001184278.1 SEC23

Other Identifiers

1771120_at

7579_at

856311

GO:0000139

GO:0003400

GO:0003674

GO:0005096

GO:0005575

GO:0005737

GO:0005789

GO:0005794

GO:0006886

GO:0006888

GO:0008150

GO:0008270

GO:0012505

GO:0015031

GO:0016020

GO:0016050

GO:0016236

GO:0030127

GO:0030234

GO:0031410

GO:0033043

GO:0043167

GO:0043547

GO:0048193

GO:0051049

GO:0090114

Participates

as an output of

CSNK1D phosphorylates SEC23 (Saccharomyces cerevisiae)

Other forms of this molecule

SEC23 [ER to Golgi transport vesicle membrane]

SEC23 [cytosol]

SEC23 [endoplasmic reticulum membrane]

Inferred From

p-S742,T747 SEC23A [cytosol] (Homo sapiens)

Modified Residues

Name

O-phospho-L-serine at 742 (in Homo sapiens)

Coordinate

742

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-threonine at 747 (in Homo sapiens)

Coordinate

747

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

NP_015507.1

PRO

P15303

PDB

2QTV, 4BZI, 1M2O, 6GNI, 1M2V

Interactors (16)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q04410	3	phospho-GRH1 [Golgi membrane] (R-SCE-2314415) GRH1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-SCE-162984) phospho-GRH1 [Golgi membrane] (R-SCE-2172182)	0.784	6
UniProt:P40482	8	phospho-SEC24 [cytosol] (R-SCE-5685746) phospho-SEC24 [cytosol] (R-SCE-5685743) SEC24 [ER to Golgi transport vesicle membrane] (R-SCE-204021) SEC24 [ER to Golgi transport vesicle membrane] (R-SCE-204022) SEC24 [endoplasmic reticulum membrane] (R-SCE-203982) SEC24 [endoplasmic reticulum membrane] (R-SCE-203992) SEC24 [cytosol] (R-SCE-203978) SEC24 [cytosol] (R-SCE-204001)	0.78	5
UniProt:P29295	6	HRR25 [nucleoplasm] (R-SCE-421306) HRR25 [mitochondrial outer membrane] (R-SCE-9715102) HRR25 [nucleoplasm] (R-SCE-421305) HRR25 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-SCE-5685717) HRR25 [cytosol] (R-SCE-205877) HRR25 [cytosol] (R-SCE-380315)	0.697	5
UniProt:P15108	6	HSC82 [extracellular region] (R-SCE-3221946-2) HSC82 [ficolin-1-rich granule lumen] (R-SCE-6801470-2) HSC82 [secretory granule lumen] (R-SCE-6801515-2) HSC82 [plasma membrane] (R-SCE-534996-2) HSC82 [nucleoplasm] (R-SCE-5082401-2) HSC82 [cytosol] (R-SCE-192864-2)	0.688	5
UniProt:P53953	4	SFB2 [ER to Golgi transport vesicle membrane] (R-SCE-204022-2) phospho-SFB2 [cytosol] (R-SCE-5685743-2) SFB2 [endoplasmic reticulum membrane] (R-SCE-203992-2) SFB2 [cytosol] (R-SCE-203978-2)	0.678	8
UniProt:P20606	2	SAR1 [endoplasmic reticulum membrane] (R-SCE-203995) SAR1 [cytosol] (R-SCE-174678)	0.667	3
UniProt:P38968	2	SEC31 [ER to Golgi transport vesicle membrane] (R-SCE-204010) SEC31 [cytosol] (R-SCE-203983)	0.632	3
UniProt:P48415	2	SEC16 [cytosol] (R-SCE-5685731) SEC16 [cytosol] (R-SCE-5685728)	0.632	5
UniProt:O75477 ERLIN1	1	ERLIN1 [endoplasmic reticulum membrane] (R-HSA-8866518)	0.556	3
UniProt:Q9BSE2 TMM79			0.556	3
UniProt:Q8IYX7 SAXO1			0.556	3
UniProt:P38810	8	phospho-SFB3 [cytosol] (R-SCE-5694551) phospho-SFB3 [cytosol] (R-SCE-5694554) SFB3 [ER to Golgi transport vesicle membrane] (R-SCE-204020) SFB3 [ER to Golgi transport vesicle membrane] (R-SCE-204026) SFB3 [endoplasmic reticulum membrane] (R-SCE-204004) SFB3 [cytosol] (R-SCE-203990) SFB3 [cytosol] (R-SCE-203988) SFB3 [endoplasmic reticulum membrane] (R-SCE-203987)	0.547	2
UniProt:P10591 HSP71			0.527	2
UniProt:P11484 SSB1			0.527	2
UniProt:P10592	6	SSA2 [secretory granule lumen] (R-SCE-6801530) SSA2 [cytosol] (R-SCE-264476) SSA2 [extracellular region] (R-SCE-6805936) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801494) SSA2 [nucleoplasm] (R-SCE-5082380) SSA2 [nucleoplasm] (R-SCE-8932217)	0.527	2
UniProt:Q99394	2	TRS33 [cytosol] (R-SCE-5685735) TRS33 [cytosol] (R-SCE-5685733)	0.499	3

Cite Us!