TAD1 deaminates adenosine-37 in tRNA(Ala) yielding inosine-37

Stable Identifier
R-SCE-6790128
Type
Reaction [transition]
Species
Saccharomyces cerevisiae
Compartment
cytoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
TAD1 deaminates adenosine-37 in tRNA(Ala) yielding inosine-37
TAD1 deaminates adenosine-37 of tRNA(Ala) yielding inosine-37 (Gerber et al. 1998). The subcellular location of the reaction is unknown in yeast.
Literature References
PubMed ID Title Journal Year
9707437 Tad1p, a yeast tRNA-specific adenosine deaminase, is related to the mammalian pre-mRNA editing enzymes ADAR1 and ADAR2

Grosjean, H, Gerber, A, Keller, W, Melcher, T

EMBO J. 1998
Participants
Input
Output
Event Information
Go Biological Process
tRNA modification (0006400)
Catalyst Activity

tRNA-specific adenosine deaminase activity of TAD1 [cytoplasm]

Physical Entity
TAD1 [cytoplasm] (Saccharomyces cerevisiae)
Activity
tRNA-specific adenosine deaminase activity (GO:0008251)
Orthologous Events
ADAT1 deaminates adenosine-37 in tRNA(Ala) (Homo sapiens)
Authored
May, B  (2015-08-08)
Reviewed
Motorin, Y  (2015-08-25)
Jarrous, N  (2015-10-24)
Created
May, B  (2015-08-09)
Cite Us!