Reactome: A Curated Pathway Database

NOP2 methylates cytosine-2870 of 25S rRNA yielding 5-methylcytosine-2870

Stable Identifier
R-SCE-6790942
Type
Reaction
Species
Saccharomyces cerevisiae
Compartment
Summation

NOP2 methylates the carbon at the 5th position of the cytosine ring at cytidine-2870 in 25S rRNA (Sharma et al. 2013, Bourgeois et al. 2015). NOP2 also has a role in rRNA processing that is independent of its methylase activity (Bourgeois et al. 2015).

Literature References
Participants
This entity is regulated by:
Title Physical Entity Activity
rRNA (cytosine-C5-)-methyltransferase activity of NOP2 [nucleoplasm] NOP2 [nucleoplasm] rRNA (cytosine-C5-)-methyltransferase activity (0009383)
Orthologous Events