Reactome | MRS6 [cytosol]

MRS6 [cytosol]

Stable Identifier

R-SCE-6801097

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

CHM, P32864

Locations in the PathwayBrowser

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Gene expression (Transcription) (Saccharomyces cerevisiae)

- RNA Polymerase II Transcription (Saccharomyces cerevisiae)
  - Generic Transcription Pathway (Saccharomyces cerevisiae)
    - Transcriptional Regulation by TP53 (Saccharomyces cerevisiae)
      - TP53 Regulates Transcription of Cell Death Genes (Saccharomyces cerevisiae)
        
        TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain (Saccharomyces cerevisiae)
        
        CHM binds RGGT (Saccharomyces cerevisiae)
        
        MRS6 [cytosol] (Saccharomyces cerevisiae)
        
        RGGT:CHM [plasma membrane] (Saccharomyces cerevisiae)
        
        MRS6 [cytosol] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P32864

Gene Names

MRS6

Reference Genes

BioGPS Gene:854552 MRS6

ENSEMBL:YOR370C

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YOR370C MRS6

Monarch:854552 MRS6

NCBI Gene:854552 MRS6

SGD:YOR370C

Reference Transcript

RefSeq:NM_001183790.1 MRS6

Other Identifiers

1772606_at

8169_at

854552

GO:0003674

GO:0004663

GO:0005092

GO:0005096

GO:0005515

GO:0005575

GO:0005634

GO:0005737

GO:0005829

GO:0005968

GO:0006605

GO:0006612

GO:0006888

GO:0007264

GO:0008150

GO:0015031

GO:0016020

GO:0016192

GO:0016740

GO:0017137

GO:0018344

GO:0019899

GO:0023052

GO:0030234

GO:0031267

GO:0048193

GO:0090630

Participates

as a member of

GDIs,CHMs [cytosol] (Saccharomyces cerevisiae)

as an input of

as a component of

Other forms of this molecule

MRS6 [cytosol]

Inferred From

CHMs [cytosol] (Homo sapiens)

CHM [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_015015.1

PRO

P32864

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P32432 SFP1			0.738	5
UniProt:P36017	7	GGC-RAB31 [early endosome membrane] (R-SCE-8877278) GGC-RAB22A [cytosol] (R-SCE-8873776) GGC-RAB20 [cytosol] (R-SCE-8873778) RAB20 [cytosol] (R-SCE-8873710) RAB22A [cytosol] (R-SCE-8873686) RAB31 [plasma membrane] (R-SCE-6804813) RAB31 [secretory granule membrane] (R-SCE-6804797)	0.678	4
UniProt:P36018	18	RAB5C [Golgi membrane] (R-SCE-434334) RAB5C [cytoplasmic vesicle membrane] (R-SCE-434198) GGC-RAB5A [early endosome membrane] (R-SCE-8875323) GGC-RAB5B [early endosome membrane] (R-SCE-8875327) GGC-RAB5C [early endosome membrane] (R-SCE-8875331) GGC-RAB5A [cytosol] (R-SCE-8870432) GGC-RAB5B [cytosol] (R-SCE-8870434) GGC-RAB17 [cytosol] (R-SCE-8873764) GGC-RAB5C [cytosol] (R-SCE-8870436) RAB17 [cytosol] (R-SCE-8873703) RAB5B [cytosol] (R-SCE-8870412) RAB5C [cytosol] (R-SCE-8870413) RAB5A [endosome membrane] (R-SCE-452257) RAB5A [cytosol] (R-SCE-2201187) RAB5C [plasma membrane] (R-SCE-6806265) RAB5C [azurophil granule membrane] (R-SCE-6799338) RAB5B [plasma membrane] (R-SCE-6804984) RAB5B [secretory granule membrane] (R-SCE-6804966)	0.667	3
UniProt:P38146	11	GGC-RAB5A [early endosome membrane] (R-SCE-8875323-2) GGC-RAB5B [early endosome membrane] (R-SCE-8875327-2) GGC-RAB5A [cytosol] (R-SCE-8870432-2) GGC-RAB5B [cytosol] (R-SCE-8870434-2) GGC-RAB17 [cytosol] (R-SCE-8873764-2) RAB17 [cytosol] (R-SCE-8873703-2) RAB5B [cytosol] (R-SCE-8870412-2) RAB5A [endosome membrane] (R-SCE-452257-2) RAB5A [cytosol] (R-SCE-2201187-2) RAB5B [plasma membrane] (R-SCE-6804984-2) RAB5B [secretory granule membrane] (R-SCE-6804966-2)	0.667	3
UniProt:Q99260	14	RAB6A [trans-Golgi network membrane] (R-SCE-6810981) RAB6B [trans-Golgi network membrane] (R-SCE-6810985) RAB6B [Golgi membrane] (R-SCE-8849249) GGC-RAB6A [trans-Golgi network membrane] (R-SCE-8876079) GGC-RAB6B [trans-Golgi network membrane] (R-SCE-8876081) GGC-RAB6A [cytosol] (R-SCE-8874052) GGC-RAB6B [cytosol] (R-SCE-8874055) GGC-RAB41 [cytosol] (R-SCE-8874030) RAB41 [cytosol] (R-SCE-8873689) RAB6A [cytosol] (R-SCE-6810979) RAB6B [cytosol] (R-SCE-6810983) RAB6A [plasma membrane] (R-SCE-6804981) RAB6A [secretory granule membrane] (R-SCE-6804970) RAB6A [Golgi membrane] (R-SCE-1604442)	0.553	2
UniProt:P01123	20	phospho-p-T191-RAB1B [Golgi membrane] (R-SCE-2422374) phospho-p-T195-RAB1A [Golgi membrane] (R-SCE-2172190) RAB1B [Golgi membrane] (R-SCE-2422381) RAB1A [Golgi membrane] (R-SCE-2167938) RAB1B [cytosol] (R-SCE-5685727) RAB1A [cytosol] (R-SCE-5685725) RAB1A [transport vesicle] (R-SCE-6808796) RAB1B [transport vesicle] (R-SCE-6808799) RAB1A [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-SCE-6807766) RAB1B [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-SCE-6807768) RAB43 [cytosol] (R-SCE-6813902) RAB19 [cytosol] (R-SCE-8873714) GGC-RAB19 [cytosol] (R-SCE-8873773) GGC-RAB43 [cytosol] (R-SCE-8874038) GGC-RAB1B [cytosol] (R-SCE-8870426) GGC-RAB1A [cytosol] (R-SCE-8870424) GGC-RAB1B [transport vesicle membrane] (R-SCE-8877470) GGC-RAB1A [transport vesicle membrane] (R-SCE-8877472) RAB43 [trans-Golgi network membrane] (R-SCE-6814810) RAB1A [endoplasmic reticulum membrane] (R-SCE-6810974)	0.547	2
UniProt:P36019	7	GGC-RAB31 [early endosome membrane] (R-SCE-8877278-2) GGC-RAB31 [cytosol] (R-SCE-8873974) GGC-RAB20 [cytosol] (R-SCE-8873778-2) RAB20 [cytosol] (R-SCE-8873710-2) RAB31 [cytosol] (R-SCE-8873690) RAB31 [plasma membrane] (R-SCE-6804813-2) RAB31 [secretory granule membrane] (R-SCE-6804797-2)	0.547	2

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