Reactome | MCM3 [nucleoplasm]

MCM3 [nucleoplasm]

Stable Identifier

R-SCE-68546

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

P24279

Locations in the PathwayBrowser for interactor UniProt:P53840

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External Reference Information

External Reference

UniProt:P24279 MCM3

Gene Names

MCM3, YEL032W, SYGP-ORF23

Chain

chain:1-971

Reference Genes

BioGPS Gene:856680 MCM3

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YEL032W MCM3

Monarch:856680 MCM3

NCBI Gene:856680 MCM3

Reference Transcript

RefSeq:NM_001178847.1 MCM3

Other Identifiers

1775015_at

5758_at

856680

GO:0000166

GO:0000278

GO:0000727

GO:0000781

GO:0003674

GO:0003677

GO:0003682

GO:0003688

GO:0003697

GO:0004386

GO:0005515

GO:0005524

GO:0005575

GO:0005634

GO:0005654

GO:0005656

GO:0005694

GO:0005737

GO:0006260

GO:0006267

GO:0006268

GO:0006270

GO:0006271

GO:0006279

GO:0006281

GO:0006310

GO:0006325

GO:0006348

GO:0006974

GO:0008150

GO:0016787

GO:0016887

GO:0017116

GO:0030466

GO:0031261

GO:0031298

GO:0031509

GO:0032200

GO:0032508

GO:0042555

GO:0043167

GO:0043596

GO:0051321

GO:0071162

GO:0140657

GO:1902975

GO:1904931

Participates

as an output of

Mcm4,6,7 trimer forms and associates with the replication fork (Saccharomyces cerevisiae)

as an input of

MCM3 binds MCM5 (Saccharomyces cerevisiae)

as a component of

MCM3:MCM5 [nucleoplasm] (Saccharomyces cerevisiae)

Other forms of this molecule

yMcm3 [nucleoplasm]

Inferred From

MCM3 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_010882.1

OpenTargets

ENSG00000112118

IntEnz

3.6.4.12

PRO

P24279

PDB

6PTJ, 5V8F, 7V3V, 6RQC, 7Z13, 6WGI, 6F0L, 6U0M, 8XGC, 7PMN, 8KG6, 3JA8, 3JC6, 6WGC, 8W7S, 3JC5, 8B9A, 7W8G, 7P5Z, 6PTN, 7PT6, 6HV9, 8W7M, 7P30, 8KG8, 8KG9, 6PTO, 7QHS, 8B9B, 6EYC, 6SKL, 7PT7, 5U8S, 6WGF, 8B9C, 5XF8, 7V3U, 5BK4, 6SKO, 5U8T, 3JC7, 7PMK, 6WGG

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P29469 MCM2	2	MCM2 [nucleoplasm] (R-SCE-68557) yMcm2 [nucleoplasm] (R-SCE-169497)	0.891	9
UniProt:P29496 MCM5	2	yMcm5 [nucleoplasm] (R-SCE-169511) MCM5 [nucleoplasm] (R-SCE-68551)	0.87	6
UniProt:Q08032	1	CDC45 [nucleoplasm] (R-SCE-68563)	0.731	4
UniProt:P30665 MCM4	2	yMcm4 [nucleoplasm] (R-SCE-169496) MCM4 [nucleoplasm] (R-SCE-68549)	0.725	4
UniProt:P38132 MCM7	2	yMcm7 [nucleoplasm] (R-SCE-169505) MCM7 [nucleoplasm] (R-SCE-68555)	0.688	3
UniProt:P32354	1	MCM10 [nucleoplasm] (R-SCE-68403)	0.564	2
UniProt:Q9BTE3-2 MCMBP			0.556	3
UniProt:P53091 MCM6	2	yMcm6 [nucleoplasm] (R-SCE-169504) MCM6 [nucleoplasm] (R-SCE-68553)	0.527	2
UniProt:Q03406	1	SLD5 [nucleoplasm] (R-SCE-176963)	0.527	3
UniProt:Q01454 CTF4			0.527	2
UniProt:P53840	1	TOF1 [nucleoplasm] (R-SCE-5684982)	0.527	2
UniProt:Q12306	5	SMT3 [cytosol] (R-SCE-4656941) SMT3 [nucleoplasm] (R-SCE-3730622) SMT3 [nucleoplasm] (R-SCE-3730616) SMT3 [nucleoplasm] (R-SCE-877304) SMT3 [nucleoplasm] (R-SCE-2990831)	0.524	2
UniProt:P47112 TAH11	1	yCDT1 [nucleoplasm] (R-SCE-9749306)	0.495	3
UniProt:P09119 CDC6	5	CDC6 [cytosol] (R-SCE-113566) phospho-p-CDC6 [cytosol] (R-SCE-68583) phospho-p-CDC6 [nucleoplasm] (R-SCE-5661317) yCDC6 [nucleoplasm] (R-SCE-9749328) CDC6 [nucleoplasm] (R-SCE-68542)	0.488	2