Reactome | MCM6 [nucleoplasm]

MCM6 [nucleoplasm]

Stable Identifier

R-SCE-68553

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

P53091

Locations in the PathwayBrowser for interactor UniProt:P53840

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External Reference Information

External Reference

UniProt:P53091 MCM6

Gene Names

MCM6, YGL201C

Chain

chain:1-1017

Reference Genes

BioGPS Gene:852673 MCM6

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YGL201C MCM6

Monarch:852673 MCM6

NCBI Gene:852673 MCM6

Reference Transcript

RefSeq:NM_001181066.1 MCM6

Other Identifiers

1776707_at

5224_at

852673

GO:0000166

GO:0000278

GO:0000727

GO:0003674

GO:0003677

GO:0003678

GO:0003688

GO:0003697

GO:0004386

GO:0005515

GO:0005524

GO:0005575

GO:0005634

GO:0005654

GO:0005656

GO:0005694

GO:0005737

GO:0006260

GO:0006267

GO:0006268

GO:0006270

GO:0006271

GO:0006279

GO:0006281

GO:0006310

GO:0006974

GO:0007049

GO:0008150

GO:0008270

GO:0009378

GO:0016787

GO:0016887

GO:0017116

GO:0031261

GO:0031298

GO:0032508

GO:0042555

GO:0043138

GO:0043142

GO:0043167

GO:0043596

GO:0051321

GO:0071162

GO:0097373

GO:0140657

GO:1902969

GO:1990518

Participates

as an input of

MCM4, MCM6 and MCM7 form a heterotrimer (Saccharomyces cerevisiae)

as a component of

MCM4:MCM6:MCM7 [nucleoplasm] (Saccharomyces cerevisiae)

Other forms of this molecule

yMcm6 [nucleoplasm]

Inferred From

MCM6 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_011314.2

OpenTargets

ENSG00000076003

PRO

P53091

PDB

7W8G, 6WGF, 5V8F, 8KG8, 5U8S, 8B9B, 8KG6, 6HV9, 7P5Z, 8B9C, 5U8T, 8W7M, 6WGG, 6F0L, 7PT6, 7V3V, 6PTN, 6U0M, 6SKO, 7PT7, 6PTO, 8B9A, 8XGC, 6PTJ, 7P30, 3JC7, 7PMN, 7V3U, 7PMK, 7Z13, 6SKL, 5XF8, 7QHS, 8W7S, 6WGI, 6RQC, 8KG9, 3JA8, 5BK4, 3JC5, 6EYC, 3JC6

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P29469 MCM2	2	MCM2 [nucleoplasm] (R-SCE-68557) yMcm2 [nucleoplasm] (R-SCE-169497)	0.879	8
UniProt:P30665 MCM4	2	yMcm4 [nucleoplasm] (R-SCE-169496) MCM4 [nucleoplasm] (R-SCE-68549)	0.813	8
UniProt:P32354	1	MCM10 [nucleoplasm] (R-SCE-68403)	0.806	6
UniProt:Q08032	1	CDC45 [nucleoplasm] (R-SCE-68563)	0.793	5
UniProt:P47112 TAH11	1	yCDT1 [nucleoplasm] (R-SCE-9749306)	0.652	4
UniProt:P29496 MCM5	2	yMcm5 [nucleoplasm] (R-SCE-169511) MCM5 [nucleoplasm] (R-SCE-68551)	0.643	3
UniProt:P53840	1	TOF1 [nucleoplasm] (R-SCE-5684982)	0.527	2
UniProt:Q01454 CTF4			0.527	2
UniProt:Q12488	1	PSF1 [nucleoplasm] (R-SCE-176955)	0.527	2
UniProt:P02309	14	HHF2 [nucleoplasm] (R-SCE-4570518) HHF2 [nucleoplasm] (R-SCE-212078) HHF2 [nucleoplasm] (R-SCE-4568744) HHF2 [nucleoplasm] (R-SCE-5229015) HHF2 [nucleoplasm] (R-SCE-4754243) HHF2 [nucleoplasm] (R-SCE-4754240) HHF2 [nucleoplasm] (R-SCE-5651656) HHF2 [nucleoplasm] (R-SCE-427469) HHF2 [nucleoplasm] (R-SCE-4568748) HHF2 [nucleoplasm] (R-SCE-4568758) HHF2 [nucleoplasm] (R-SCE-3451124) HHF2 [nucleoplasm] (R-SCE-5423110) HHF2 [nucleoplasm] (R-SCE-5651652) HHF2 [nucleoplasm] (R-SCE-181902)	0.527	2
UniProt:P24279 MCM3	2	yMcm3 [nucleoplasm] (R-SCE-169513) MCM3 [nucleoplasm] (R-SCE-68546)	0.527	2
UniProt:Q12306	5	SMT3 [cytosol] (R-SCE-4656941) SMT3 [nucleoplasm] (R-SCE-3730622) SMT3 [nucleoplasm] (R-SCE-3730616) SMT3 [nucleoplasm] (R-SCE-877304) SMT3 [nucleoplasm] (R-SCE-2990831)	0.524	2

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