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PUP1 [cytosol]
Stable Identifier
R-SCE-68759
Type
Protein [EntityWithAccessionedSequence]
Species
Saccharomyces cerevisiae
Compartment
cytosol
Synonyms
PSMB7, P25043
Locations in the PathwayBrowser
Expand all
Cell Cycle (Saccharomyces cerevisiae)
Cell Cycle Checkpoints (Saccharomyces cerevisiae)
G1/S DNA Damage Checkpoints (Saccharomyces cerevisiae)
p53-Independent G1/S DNA damage checkpoint (Saccharomyces cerevisiae)
p53-Independent DNA Damage Response (Saccharomyces cerevisiae)
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A (Saccharomyces cerevisiae)
Proteolytic degradation of ubiquitinated-Cdc25A (Saccharomyces cerevisiae)
26S proteasome [cytosol] (Saccharomyces cerevisiae)
PUP1 [cytosol] (Saccharomyces cerevisiae)
Cell Cycle, Mitotic (Saccharomyces cerevisiae)
Mitotic G2-G2/M phases (Saccharomyces cerevisiae)
G2/M Transition (Saccharomyces cerevisiae)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis (Saccharomyces cerevisiae)
Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Saccharomyces cerevisiae)
26S proteasome [cytosol] (Saccharomyces cerevisiae)
PUP1 [cytosol] (Saccharomyces cerevisiae)
Proteasome-mediated degradation of PolyUb-FBXL7 (Saccharomyces cerevisiae)
26S proteasome [cytosol] (Saccharomyces cerevisiae)
PUP1 [cytosol] (Saccharomyces cerevisiae)
S Phase (Saccharomyces cerevisiae)
Synthesis of DNA (Saccharomyces cerevisiae)
Switching of origins to a post-replicative state (Saccharomyces cerevisiae)
CDK-mediated phosphorylation and removal of Cdc6 (Saccharomyces cerevisiae)
Ubiquitinated Cdc6 is degraded by the proteasome (Saccharomyces cerevisiae)
26S proteasome [cytosol] (Saccharomyces cerevisiae)
PUP1 [cytosol] (Saccharomyces cerevisiae)
Orc1 removal from chromatin (Saccharomyces cerevisiae)
Ubiquitinated Orc1 is degraded by the proteasome (Saccharomyces cerevisiae)
26S proteasome [cytosol] (Saccharomyces cerevisiae)
PUP1 [cytosol] (Saccharomyces cerevisiae)
Cellular responses to stimuli (Saccharomyces cerevisiae)
Cellular responses to stress (Saccharomyces cerevisiae)
Cellular response to chemical stress (Saccharomyces cerevisiae)
KEAP1-NFE2L2 pathway (Saccharomyces cerevisiae)
ub UBXN7 is degraded by the 26S proteasome (Saccharomyces cerevisiae)
26S proteasome [cytosol] (Saccharomyces cerevisiae)
PUP1 [cytosol] (Saccharomyces cerevisiae)
DNA Replication (Saccharomyces cerevisiae)
Synthesis of DNA (Saccharomyces cerevisiae)
Switching of origins to a post-replicative state (Saccharomyces cerevisiae)
CDK-mediated phosphorylation and removal of Cdc6 (Saccharomyces cerevisiae)
Ubiquitinated Cdc6 is degraded by the proteasome (Saccharomyces cerevisiae)
26S proteasome [cytosol] (Saccharomyces cerevisiae)
PUP1 [cytosol] (Saccharomyces cerevisiae)
Orc1 removal from chromatin (Saccharomyces cerevisiae)
Ubiquitinated Orc1 is degraded by the proteasome (Saccharomyces cerevisiae)
26S proteasome [cytosol] (Saccharomyces cerevisiae)
PUP1 [cytosol] (Saccharomyces cerevisiae)
Immune System (Saccharomyces cerevisiae)
Adaptive Immune System (Saccharomyces cerevisiae)
Class I MHC mediated antigen processing & presentation (Saccharomyces cerevisiae)
Antigen processing-Cross presentation (Saccharomyces cerevisiae)
Cross-presentation of soluble exogenous antigens (endosomes) (Saccharomyces cerevisiae)
Proteasomal clevage of exogenous antigen (Saccharomyces cerevisiae)
26S proteasome [cytosol] (Saccharomyces cerevisiae)
PUP1 [cytosol] (Saccharomyces cerevisiae)
Antigen processing: Ubiquitination & Proteasome degradation (Saccharomyces cerevisiae)
Proteasomal cleavage of substrate (Saccharomyces cerevisiae)
26S proteasome [cytosol] (Saccharomyces cerevisiae)
PUP1 [cytosol] (Saccharomyces cerevisiae)
Cytokine Signaling in Immune system (Saccharomyces cerevisiae)
TNFR2 non-canonical NF-kB pathway (Saccharomyces cerevisiae)
26Sproteasome degrades K48polyUb-NIK (Saccharomyces cerevisiae)
26S proteasome [cytosol] (Saccharomyces cerevisiae)
PUP1 [cytosol] (Saccharomyces cerevisiae)
Metabolism of proteins (Saccharomyces cerevisiae)
Post-translational protein modification (Saccharomyces cerevisiae)
Deubiquitination (Saccharomyces cerevisiae)
Ub-specific processing proteases (Saccharomyces cerevisiae)
ADRM1:26S proteaseome binds USP14 (Saccharomyces cerevisiae)
ADRM1:26S proteasome [cytosol] (Saccharomyces cerevisiae)
26S proteasome [cytosol] (Saccharomyces cerevisiae)
PUP1 [cytosol] (Saccharomyces cerevisiae)
ADRM1:26S proteasome:USP14 [cytosol] (Saccharomyces cerevisiae)
ADRM1:26S proteasome [cytosol] (Saccharomyces cerevisiae)
26S proteasome [cytosol] (Saccharomyces cerevisiae)
PUP1 [cytosol] (Saccharomyces cerevisiae)
Neddylation (Saccharomyces cerevisiae)
ub UBXN7 is degraded by the 26S proteasome (Saccharomyces cerevisiae)
26S proteasome [cytosol] (Saccharomyces cerevisiae)
PUP1 [cytosol] (Saccharomyces cerevisiae)
Signal Transduction (Saccharomyces cerevisiae)
Intracellular signaling by second messengers (Saccharomyces cerevisiae)
PIP3 activates AKT signaling (Saccharomyces cerevisiae)
PTEN Regulation (Saccharomyces cerevisiae)
Regulation of PTEN stability and activity (Saccharomyces cerevisiae)
Proteasome degrades polyubiquitinated PTEN (Saccharomyces cerevisiae)
26S proteasome [cytosol] (Saccharomyces cerevisiae)
PUP1 [cytosol] (Saccharomyces cerevisiae)
MAPK family signaling cascades (Saccharomyces cerevisiae)
MAPK6/MAPK4 signaling (Saccharomyces cerevisiae)
MAPK6 is degraded by the 26S proteasome (Saccharomyces cerevisiae)
26S proteasome [cytosol] (Saccharomyces cerevisiae)
PUP1 [cytosol] (Saccharomyces cerevisiae)
External Reference Information
External Reference
UniProt:P25043
Gene Names
PUP1
Reference Genes
BioGPS Gene:854328 PUP1
ENSEMBL:YOR157C
KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YOR157C PUP1
Monarch:854328 PUP1
NCBI Gene:854328 PUP1
SGD:YOR157C
Reference Transcript
RefSeq:NM_001183576.3 PUP1
Other Identifiers
1770049_at
8404_at
854328
GO:0000502
GO:0003674
GO:0004175
GO:0004298
GO:0005515
GO:0005575
GO:0005634
GO:0005737
GO:0005783
GO:0005789
GO:0005829
GO:0005839
GO:0006508
GO:0008150
GO:0008233
GO:0010498
GO:0010499
GO:0012505
GO:0016020
GO:0016787
GO:0019774
GO:0034515
GO:0043161
GO:0051603
Participates
as a component of
26S proteasome [cytosol] (Saccharomyces cerevisiae)
Other forms of this molecule
PUP1 [secretory granule lumen]
PUP1 [extracellular region]
PUP1 [ficolin-1-rich granule lumen]
PUP1 [cytosol]
Inferred From
PSMB7 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_014800.3
PRO
P25043
PDB
8T0M
,
5L5P
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3BDM
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