Reactome | RPS26A [cytosol]

RPS26A [cytosol]

Stable Identifier

R-SCE-72359

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

RPS26, P39938

Locations in the PathwayBrowser

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Metabolism of RNA (Saccharomyces cerevisiae)

- Nonsense-Mediated Decay (NMD) (Saccharomyces cerevisiae)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Saccharomyces cerevisiae)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Saccharomyces cerevisiae)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Saccharomyces cerevisiae)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Saccharomyces cerevisiae)
        
        80S ribosome [cytosol] (Saccharomyces cerevisiae)
        
        40S ribosomal complex [cytosol] (Saccharomyces cerevisiae)
        
        RPS26A [cytosol] (Saccharomyces cerevisiae)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Saccharomyces cerevisiae)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Saccharomyces cerevisiae)
        
        80S ribosome [cytosol] (Saccharomyces cerevisiae)
        
        40S ribosomal complex [cytosol] (Saccharomyces cerevisiae)
        
        RPS26A [cytosol] (Saccharomyces cerevisiae)
    - SMG6 hydrolyzes mRNA with premature termination codon (Saccharomyces cerevisiae)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Saccharomyces cerevisiae)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Saccharomyces cerevisiae)
        
        80S ribosome [cytosol] (Saccharomyces cerevisiae)
        
        40S ribosomal complex [cytosol] (Saccharomyces cerevisiae)
        
        RPS26A [cytosol] (Saccharomyces cerevisiae)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Saccharomyces cerevisiae)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Saccharomyces cerevisiae)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Saccharomyces cerevisiae)
        
        80S ribosome [cytosol] (Saccharomyces cerevisiae)
        
        40S ribosomal complex [cytosol] (Saccharomyces cerevisiae)
        
        RPS26A [cytosol] (Saccharomyces cerevisiae)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Saccharomyces cerevisiae)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Saccharomyces cerevisiae)
        
        80S ribosome [cytosol] (Saccharomyces cerevisiae)
        
        40S ribosomal complex [cytosol] (Saccharomyces cerevisiae)
        
        RPS26A [cytosol] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P39938 RPS26A

Gene Names

RPS26A, RPS26, YGL189C, G1355

Chain

chain:1-119

Reference Genes

BioGPS Gene:852686 RPS26A

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YGL189C RPS26A

Monarch:852686 RPS26A

NCBI Gene:852686 RPS26A

Reference Transcript

RefSeq:NM_001181054.1 RPS26A

Other Identifiers

1770502_x_at

1771492_at

5190_i_at

5191_f_at

852686

GO:0002181

GO:0003674

GO:0003723

GO:0003729

GO:0003735

GO:0005198

GO:0005515

GO:0005575

GO:0005737

GO:0005829

GO:0005840

GO:0006407

GO:0006412

GO:0008150

GO:0008270

GO:0015931

GO:0022627

GO:0042255

GO:0043167

GO:0051169

GO:0070925

GO:1990904

Participates

as a component of

40S ribosomal complex [cytosol] (Saccharomyces cerevisiae)

Other forms of this molecule

RPS26A [nucleoplasm]

RPS26A [cytosol]

Inferred From

RPS26 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_011326.1

PRO

P39938

PDB

6T7I, 5JUU, 6G04, 4V88, 4V8Z, 8CAH, 5MC6, 5JUP, 6ZCE, 5JUS, 5FCI, 5JUT, 3J78, 7ZW0, 5JUO, 4V8Y, 6SV4, 7MPJ, 6ZU9, 7ZUW, 3J77, 5DGE, 3J6Y, 8CAS, 6SNT, 8BQD, 4V92, 6T7T, 6T83, 5LL6, 3J6X

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