Reactome | RPL36B [cytosol]

RPL36B [cytosol]

Stable Identifier

R-SCE-72464

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

RPL36, O14455

Locations in the PathwayBrowser

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Metabolism of RNA (Saccharomyces cerevisiae)

- Nonsense-Mediated Decay (NMD) (Saccharomyces cerevisiae)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Saccharomyces cerevisiae)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Saccharomyces cerevisiae)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Saccharomyces cerevisiae)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Saccharomyces cerevisiae)
        
        80S ribosome [cytosol] (Saccharomyces cerevisiae)
        
        60S ribosomal complex [cytosol] (Saccharomyces cerevisiae)
        
        Homologues of RPL36 [cytosol] (Saccharomyces cerevisiae)
        
        RPL36B [cytosol] (Saccharomyces cerevisiae)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Saccharomyces cerevisiae)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Saccharomyces cerevisiae)
        
        80S ribosome [cytosol] (Saccharomyces cerevisiae)
        
        60S ribosomal complex [cytosol] (Saccharomyces cerevisiae)
        
        Homologues of RPL36 [cytosol] (Saccharomyces cerevisiae)
        
        RPL36B [cytosol] (Saccharomyces cerevisiae)
    - SMG6 hydrolyzes mRNA with premature termination codon (Saccharomyces cerevisiae)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Saccharomyces cerevisiae)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Saccharomyces cerevisiae)
        
        80S ribosome [cytosol] (Saccharomyces cerevisiae)
        
        60S ribosomal complex [cytosol] (Saccharomyces cerevisiae)
        
        Homologues of RPL36 [cytosol] (Saccharomyces cerevisiae)
        
        RPL36B [cytosol] (Saccharomyces cerevisiae)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Saccharomyces cerevisiae)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Saccharomyces cerevisiae)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Saccharomyces cerevisiae)
        
        80S ribosome [cytosol] (Saccharomyces cerevisiae)
        
        60S ribosomal complex [cytosol] (Saccharomyces cerevisiae)
        
        Homologues of RPL36 [cytosol] (Saccharomyces cerevisiae)
        
        RPL36B [cytosol] (Saccharomyces cerevisiae)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Saccharomyces cerevisiae)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Saccharomyces cerevisiae)
        
        80S ribosome [cytosol] (Saccharomyces cerevisiae)
        
        60S ribosomal complex [cytosol] (Saccharomyces cerevisiae)
        
        Homologues of RPL36 [cytosol] (Saccharomyces cerevisiae)
        
        RPL36B [cytosol] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:O14455 RPL36B

Gene Names

RPL36B, RPL39B, YPL249C-A, YPL249BC

Chain

initiator methionine:, chain:2-100

Reference Genes

BioGPS Gene:855826 RPL36B

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YPL249C-A RPL36B

Monarch:855826 RPL36B

NCBI Gene:855826 RPL36B

Reference Transcript

RefSeq:NM_001184312.1 RPL36B

Other Identifiers

1774525_at

8000_i_at

855826

9421_s_at

GO:0002181

GO:0003674

GO:0003723

GO:0003735

GO:0005198

GO:0005515

GO:0005575

GO:0005737

GO:0005829

GO:0005840

GO:0006412

GO:0008150

GO:0022625

GO:1990904

Participates

as a member of

Homologues of RPL36 [cytosol] (Saccharomyces cerevisiae)

Other forms of this molecule

RPL36B [cytosol]

Inferred From

RPL36 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_015074.1

PRO

O14455

PDB

6EM5, 6EM3, 6EM1, 6EM4

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