Reactome | SUMO1 [nucleoplasm]

SUMO1 [nucleoplasm]

Stable Identifier

R-SCE-877304

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

Q12306

Locations in the PathwayBrowser for interactor UniProt:P15873

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External Reference Information

External Reference

UniProt:Q12306

Reference Genes

BioGPS Gene:852122

ENSEMBL:YDR510W

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YDR510W

Monarch:852122

NCBI Gene:852122

SGD:YDR510W

Reference Transcript

RefSeq:NM_001180818.1

Other Identifiers

1EUV

1L2N

2EKE

3PGE

3QHT

3TIX

3UF8

3UQA

3UQB

3V60

3V61

3V62

3VAW

4932.YDR510W

4FN2

4G50

4GGQ

4GIV

5D6J

5JNE

5KLX

AAB01675.1

AAB64951.1

AAS56500.1

DAA12341.1

EntrezGene:852122

GO:0000794

GO:0003674

GO:0005515

GO:0005575

GO:0005634

GO:0005694

GO:0005737

GO:0005856

GO:0005938

GO:0005940

GO:0008150

GO:0016925

GO:0018193

GO:0031386

GO:0042802

GO:0070647

IPR000626

IPR022617

IPR029071

NM_001180818.1

NP_010798.1

PF11976

SM00213

UPI00001122F6

YDR510W

YDR510W_mRNA

Participant Of

input

Conjugation of SUMO1 to UBA2:SAE1

output

SENP1,2,5 proteolytically process SUMO1

Other forms of this molecule

K14-UBE2I-G97-SUMO1 [nucleoplasm]

PIAS4-G97-SUMO1 [nucleoplasm]

K2592-RANBP2-G97-SUMO1 [nuclear envelope]

ING2-G97-SUMO1 [nucleoplasm]

DDX17-G97-SUMO1 [nucleoplasm]

DDX5-G97-SUMO1 [nucleoplasm]

SIN3A-G97-SUMO1 [nucleoplasm]

HIPK2-G97-SUMO1 [nucleoplasm]

TOP2B-G97-SUMO1 [nucleoplasm]

TOP1-G97-SUMO1 [nucleoplasm]

TOP2A-G97-SUMO1 [nucleoplasm]

K-PCNA-G97-SUMO1 [nucleoplasm]

STAG2-G97-SUMO1 [nucleoplasm]

RAD21-G97-SUMO1 [nucleoplasm]

K411-RAD52-G97-SUMO1 [nucleoplasm]

XPC-G97-SUMO1 [nucleoplasm]

TP53BP1-G97-SUMO1 [nucleoplasm]

K289-MITF-G97-SUMO1 [nucleoplasm]

K114-FOXL2-G97-SUMO1 [nucleoplasm]

HNRNPC-G97-SUMO1 [nucleoplasm]

K467-NOP58-G97-SUMO1 [nucleoplasm]

K444-HDAC1-G97-SUMO1 [nucleoplasm]

HDAC2-G97-SUMO1 [nucleoplasm]

SUZ12-G97-SUMO1 [nucleoplasm]

UBE2I-G97-SUMO1 [nucleoplasm]

UBA2-G97-SUMO1 [nucleoplasm]

SUMO1(2-101) [nucleoplasm]

HIST1H4-G97-SUMO1 [nucleoplasm]

HDAC4-G97-SUMO1 [nucleoplasm]

Inferred From

SUMO1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_010798.1

PRO

Q12306

PDB

3TIX, 3PGE, 6P81, 4G50, 5KLX, 3VAW, 4FN2, 3UQA, 3UQB, 1L2N, 3V62, 5YC2, 6RPQ, 5D6J, 4GIV, 3V61, 3V60, 1EUV, 5V8T, 2EKE, 5JNE, 6Q2S, 3UF8, 4GGQ, 5YCA, 6CFP, 3QHT

Interactors (33)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q08204	1	SMC5 [nucleoplasm] (R-SCE-2993751)	0.728	5
UniProt:P14291 RED1			0.704	9
UniProt:P12954 SRS2			0.704	4
UniProt:P15873	4	PCNA [nucleoplasm] (R-SCE-68439) SUMO1-K164,K254,K-PCNA [nucleoplasm] (R-SCE-4615861) MonoUb-K164-PCNA [nucleoplasm] (R-SCE-5651986) ISG-K164,ISG-K168-PCNA [nucleoplasm] (R-SCE-5653768)	0.698	6
UniProt:Q12050 ELG1			0.683	11
UniProt:Q12306	30	PIAS4-G97-SUMO1 [nucleoplasm] (R-SCE-3968375) K14-UBE2I-G97-SUMO1 [nucleoplasm] (R-SCE-4085334) K2592-RANBP2-G97-SUMO1 [nuclear envelope] (R-SCE-4551627) ING2-G97-SUMO1 [nucleoplasm] (R-SCE-4086096) DDX17-G97-SUMO1 [nucleoplasm] (R-SCE-3900210) DDX5-G97-SUMO1 [nucleoplasm] (R-SCE-3900212) SIN3A-G97-SUMO1 [nucleoplasm] (R-SCE-4086058) HIPK2-G97-SUMO1 [nucleoplasm] (R-SCE-4090362) TOP2B-G97-SUMO1 [nucleoplasm] (R-SCE-4641311) TOP1-G97-SUMO1 [nucleoplasm] (R-SCE-4641306) TOP2A-G97-SUMO1 [nucleoplasm] (R-SCE-4641341) K-PCNA-G97-SUMO1 [nucleoplasm] (R-SCE-4615836) STAG2-G97-SUMO1 [nucleoplasm] (R-SCE-3826645) RAD21-G97-SUMO1 [nucleoplasm] (R-SCE-3826574) K411-RAD52-G97-SUMO1 [nucleoplasm] (R-SCE-4568857) XPC-G97-SUMO1 [nucleoplasm] (R-SCE-4570452) TP53BP1-G97-SUMO1 [nucleoplasm] (R-SCE-3730731) K289-MITF-G97-SUMO1 [nucleoplasm] (R-SCE-3730738) K114-FOXL2-G97-SUMO1 [nucleoplasm] (R-SCE-3968396) HNRNPC-G97-SUMO1 [nucleoplasm] (R-SCE-4570515) K467-NOP58-G97-SUMO1 [nucleoplasm] (R-SCE-4570462) K444-HDAC1-G97-SUMO1 [nucleoplasm] (R-SCE-4616028) HDAC2-G97-SUMO1 [nucleoplasm] (R-SCE-4616032) SUZ12-G97-SUMO1 [nucleoplasm] (R-SCE-4615961) UBE2I-G97-SUMO1 [nucleoplasm] (R-SCE-3730622) UBA2-G97-SUMO1 [nucleoplasm] (R-SCE-3730616) SUMO1 [nucleoplasm] (R-SCE-877304) SUMO1(2-101) [nucleoplasm] (R-SCE-2990831) HIST1H4-G97-SUMO1 [nucleoplasm] (R-SCE-4570549) HDAC4-G97-SUMO1 [nucleoplasm] (R-SCE-4615956)	0.681	3
UniProt:P50623	3	UBE2I [nucleoplasm] (R-SCE-912481) SUMO1-K14-UBE2I [nucleoplasm] (R-SCE-4085358) SUMO1-C93-UBE2I [nucleoplasm] (R-SCE-3730617)	0.668	3
UniProt:P06778	3	phospho-p-Y104-RAD52 [nucleoplasm] (R-SCE-5686588) SUMO1-K411,K412,K414-RAD52 [nucleoplasm] (R-SCE-4568909) RAD52 [nucleoplasm] (R-SCE-62639)	0.589	2
UniProt:P53044	1	UFD1L [nucleoplasm] (R-SCE-5654993)	0.567	3
UniProt:P25694	7	VCP [ficolin-1-rich granule lumen] (R-SCE-6800425) VCP [cytosol] (R-SCE-1181251) VCP [extracellular region] (R-SCE-6806191) VCP [secretory granule lumen] (R-SCE-6801039) VCP [azurophil granule lumen] (R-SCE-6800438) VCP [nucleoplasm] (R-SCE-5643745) Me3K315-VCP [cytosol] (R-SCE-8932209)	0.567	3
UniProt:P52488	2	UBA2 [nucleoplasm] (R-SCE-947696) SUMO1-C173-UBA2 [nucleoplasm] (R-SCE-3730628)	0.558	2
UniProt:B0QYN7 B0QYN7			0.556	3
UniProt:P63279 UBE2I	8	SUMO1-C93-UBE2I [cytosol] (R-HSA-4656909) SUMO1-K14-UBE2I [nucleoplasm] (R-HSA-4085358) UBE2I [nuclear envelope] (R-HSA-4655408) UBE2I [cytosol] (R-HSA-4655342) SUMO3-C93-UBE2I [nucleoplasm] (R-HSA-3730629) SUMO2-C93-UBE2I [nucleoplasm] (R-HSA-3730619) UBE2I [nucleoplasm] (R-HSA-912481) SUMO1-C93-UBE2I [nucleoplasm] (R-HSA-3730617)	0.556	3
UniProt:P23497-2 SP100			0.556	3
UniProt:Q9HCK0 ZBT26			0.556	3
UniProt:Q03718 NSE5			0.553	2
UniProt:P38319 TYDP1			0.553	2
UniProt:Q04110 ECM11			0.553	2
UniProt:P32828 SLX5			0.553	2
UniProt:P35187	1	BLM [nucleoplasm] (R-SCE-174881)	0.527	3
UniProt:P07271 PIF1			0.524	2
UniProt:P53091 MCM6	2	MCM6 [nucleoplasm] (R-SCE-68553) yMcm6 [nucleoplasm] (R-SCE-169504)	0.524	2
UniProt:P32797 CDC13			0.524	3
UniProt:Q04437	2	XRCC5 [secretory granule lumen] (R-SCE-6801297) XRCC5 [extracellular region] (R-SCE-6806530)	0.524	2
UniProt:P30665 MCM4	2	MCM4 [nucleoplasm] (R-SCE-68549) yMcm4 [nucleoplasm] (R-SCE-169496)	0.524	2
UniProt:P24279 MCM3	2	MCM3 [nucleoplasm] (R-SCE-68546) yMcm3 [nucleoplasm] (R-SCE-169513)	0.524	2
UniProt:P32807	3	XRCC6 [extracellular region] (R-SCE-6806444) XRCC6 [secretory granule lumen] (R-SCE-6801312) XRCC6 [ficolin-1-rich granule lumen] (R-SCE-6801300)	0.524	2
UniProt:P29469 MCM2	2	MCM2 [nucleoplasm] (R-SCE-68557) yMcm2 [nucleoplasm] (R-SCE-169497)	0.524	2
UniProt:P38132 MCM7	2	MCM7 [nucleoplasm] (R-SCE-68555) yMcm7 [nucleoplasm] (R-SCE-169505)	0.524	2
UniProt:P29496 MCM5	2	MCM5 [nucleoplasm] (R-SCE-68551) yMcm5 [nucleoplasm] (R-SCE-169511)	0.524	3
UniProt:P31111 ZIP1			0.502	2
UniProt:P32908	4	SMC1A [chromosome] (R-SCE-1638774) SMC1A [cytosol] (R-SCE-2484798) SMC1A [chromosome, centromeric region] (R-SCE-2466015) SMC1A [nucleoplasm] (R-SCE-64561)	0.499	2
UniProt:P25454	2	phospho-p-T309-RAD51 [nucleoplasm] (R-SCE-5685231) RAD51 [nucleoplasm] (R-SCE-62637)	0.482	2