Reactome | DLS1 [nucleoplasm]

DLS1 [nucleoplasm]

Stable Identifier

R-SCE-8866684-2

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

POLE4, P40366

Locations in the PathwayBrowser

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Cell Cycle (Saccharomyces cerevisiae)

- Cell Cycle, Mitotic (Saccharomyces cerevisiae)
  - Mitotic G1 phase and G1/S transition (Saccharomyces cerevisiae)
    - G1/S Transition (Saccharomyces cerevisiae)
      - Activation of the pre-replicative complex (Saccharomyces cerevisiae)
        
        DNA polymerase alpha:primase binds at the origin (Saccharomyces cerevisiae)
        
        DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        DNA polymerase epsilon:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        DNA polymerase epsilon [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of POLE4 [nucleoplasm] (Saccharomyces cerevisiae)
        
        DLS1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        DNA polymerase epsilon:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        DNA polymerase epsilon [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of POLE4 [nucleoplasm] (Saccharomyces cerevisiae)
        
        DLS1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        DNA polymerase epsilon binds at the origin (Saccharomyces cerevisiae)
        
        DNA polymerase epsilon [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of POLE4 [nucleoplasm] (Saccharomyces cerevisiae)
        
        DLS1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        DNA polymerase epsilon:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        DNA polymerase epsilon [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of POLE4 [nucleoplasm] (Saccharomyces cerevisiae)
        
        DLS1 [nucleoplasm] (Saccharomyces cerevisiae)
  - S Phase (Saccharomyces cerevisiae)
    - Synthesis of DNA (Saccharomyces cerevisiae)
      - DNA replication initiation (Saccharomyces cerevisiae)
        
        The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin (Saccharomyces cerevisiae)
        
        DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        DNA polymerase epsilon:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        DNA polymerase epsilon [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of POLE4 [nucleoplasm] (Saccharomyces cerevisiae)
        
        DLS1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        DNA polymerase epsilon [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of POLE4 [nucleoplasm] (Saccharomyces cerevisiae)
        
        DLS1 [nucleoplasm] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P40366

Gene Names

DLS1

Reference Genes

BioGPS Gene:853381 DLS1

ENSEMBL:YJL065C

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YJL065C DLS1

Monarch:853381 DLS1

NCBI Gene:853381 DLS1

SGD:YJL065C

Reference Transcript

RefSeq:NM_001181498.1 DLS1

Other Identifiers

11092_at

1775531_at

853381

GO:0000781

GO:0003674

GO:0005515

GO:0005575

GO:0005634

GO:0005694

GO:0006260

GO:0006261

GO:0006325

GO:0006338

GO:0006348

GO:0006351

GO:0006355

GO:0008150

GO:0008623

GO:0031509

GO:0032200

GO:0032991

GO:0046982

Participates

as a member of

Homologues of POLE4 [nucleoplasm] (Saccharomyces cerevisiae)

Inferred From

POLE4 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_012470.1

PRO

P40366

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P10592	20	SSA2 [cytosol] (R-SCE-264476) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801512-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801496-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801494) SSA2 [extracellular region] (R-SCE-6805872-3) SSA2 [extracellular region] (R-SCE-6806500-3) SSA2 [extracellular region] (R-SCE-6805936) SSA2 [secretory granule lumen] (R-SCE-6801530) SSA2 [secretory granule lumen] (R-SCE-6801472-3) SSA2 [cytosol] (R-SCE-3371410-3) SSA2 [cytosol] (R-SCE-3371408-3) SSA2 [cytosol] (R-SCE-6792602-3) SSA2 [nucleoplasm] (R-SCE-5082380) SSA2 [nucleoplasm] (R-SCE-6792605-3) SSA2 [nucleoplasm] (R-SCE-912480-3) SSA2 [nucleoplasm] (R-SCE-5082367-3) SSA2 [nucleoplasm] (R-SCE-5252082-3) SSA2 [nucleoplasm] (R-SCE-5252088-3) SSA2 [nucleoplasm] (R-SCE-5252009-3) SSA2 [cytosol] (R-SCE-5251948-3)	0.527	2

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