Reactome | TEF1; TEF2 [cytosol]

TEF1; TEF2 [cytosol]

Stable Identifier

R-SCE-8932212

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

Me3K79-EEF1A1, P02994

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P02994

Gene Names

TEF1; TEF2

Reference Genes

BioGPS Gene:852415 TEF1; TEF2

BioGPS Gene:856195 TEF1; TEF2

ENSEMBL:YBR118W

KEGG:sce:YBR118W TEF1; TEF2

KEGG:sce:YPR080W TEF1; TEF2

Monarch:852415 TEF1; TEF2

Monarch:856195 TEF1; TEF2

NCBI Gene:852415 TEF1; TEF2

NCBI Gene:856195 TEF1; TEF2

SGD:YBR118W

UCSC:P02994 TEF1; TEF2

Reference Transcript

Other Identifiers

852415

856195

GO:0000166

GO:0000329

GO:0001933

GO:0003674

GO:0003746

GO:0003779

GO:0003924

GO:0005515

GO:0005525

GO:0005575

GO:0005737

GO:0005739

GO:0005829

GO:0005840

GO:0005853

GO:0005856

GO:0006409

GO:0006412

GO:0006414

GO:0006469

GO:0008092

GO:0008135

GO:0008150

GO:0015931

GO:0016787

GO:0017048

GO:0019003

GO:0019899

GO:0019901

GO:0031399

GO:0034198

GO:0042594

GO:0043022

GO:0043167

GO:0051015

GO:0051017

GO:0051169

GO:1904408

Participates

as an output of

N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A (Saccharomyces cerevisiae)

Other forms of this molecule

TEF1; TEF2 [cytosol]

TEF1; TEF2 [secretory granule lumen]

TEF1; TEF2 [extracellular region]

TEF1; TEF2 [ficolin-1-rich granule lumen]

TEF1; TEF2 [cytosol]

Inferred From

Me3K79-EEF1A1 [cytosol] (Homo sapiens)

Modified Residues

Name

N6,N6,N6-trimethyl-L-lysine at 79 (in Homo sapiens)

Coordinate

PsiMod Name

N6,N6,N6-trimethyl-L-lysine [MOD:00083]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6,N6,N6-trimethyl-L-lysine.

Cross References

RefSeq

NP_009676.1, NP_015405.1

ENSEMBL

YBR118W, YPR080W_mRNA, YBR118W, YPR080W, YBR118W_mRNA, YPR080W

PRO

P02994

PDB

2B7C, 2B7B, 9BDP, 1F60, 1IJE, 1G7C, 1IJF, 5O8W

Interactors (51)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P32471	2	EFB1 [cytosol] (R-SCE-156926) EFB1 [cytosol] (R-SCE-156914)	0.794	6
UniProt:P36008 EF1G2			0.592	5
UniProt:P29547	1	CAM1 [cytosol] (R-SCE-156925)	0.592	5
UniProt:P17555	2	SRV2 [extracellular region] (R-SCE-350746) SRV2 [azurophil granule lumen] (R-SCE-6798752)	0.576	3
UniProt:P35845	3	SWH1 [cytosol] (R-SCE-429725) SWH1 [cytosol] (R-SCE-2213214) SWH1 [cytosol] (R-SCE-8867527)	0.564	2
UniProt:P00817	2	IPP1 [mitochondrial matrix] (R-SCE-449918) IPP1 [cytosol] (R-SCE-71725)	0.564	2
UniProt:P10662 RT01			0.564	2
UniProt:Q62384 ZPR1			0.558	2
UniProt:P40991 NOP2	1	NOP2 [nucleoplasm] (R-SCE-6790926)	0.527	2
UniProt:P15992 HSP26			0.527	2
UniProt:P40354 NTA1			0.527	2
UniProt:Q01477	3	UBP3 [cytosol] (R-SCE-6782974) UBP3 [cytosol] (R-SCE-6782986) UBP3 [nucleoplasm] (R-SCE-3222218)	0.527	2
UniProt:Q12329 HSP42			0.527	2
UniProt:P02994	6	TEF1; TEF2 [cytosol] (R-SCE-156905) TEF1; TEF2 [secretory granule lumen] (R-SCE-6801479) TEF1; TEF2 [extracellular region] (R-SCE-6806456) TEF1; TEF2 [ficolin-1-rich granule lumen] (R-SCE-6801528) TEF1; TEF2 [cytosol] (R-SCE-8932419) TEF1; TEF2 [cytosol] (R-SCE-8932212)	0.527	2
UniProt:P38080 AKL1			0.527	2
UniProt:P04819	1	CDC9 [nucleoplasm] (R-SCE-53787)	0.527	2
UniProt:P38720	1	GND1 [cytosol] (R-SCE-71297)	0.527	2
UniProt:P32585 MED18			0.527	2
UniProt:P32345 PP4C			0.527	2
UniProt:P05453 SUP35	3	eRF3 [cytosol] (R-SCE-141686) SUP35 [cytosol] (R-SCE-8865759) SUP35 [cytosol] (R-SCE-143379)	0.527	3
UniProt:P39081	1	PCF11 [nucleoplasm] (R-SCE-72019)	0.527	2
UniProt:P04802 SYDC			0.527	3
UniProt:P20081	1	FPR1 [cytosol] (R-SCE-2026007)	0.527	2
UniProt:P32601 MSS4			0.527	2
UniProt:P38707 SYNC			0.527	3
UniProt:P15442 GCN2	2	GCN2 [cytosol] (R-SCE-9633552) p-T882,887-GCN2 [cytosol] (R-SCE-9633799)	0.527	2
UniProt:P11484	20	SSB1 [cytosol] (R-SCE-264476-4) SSB1 [cytosol] (R-SCE-3371410-4) SSB1 [cytosol] (R-SCE-3371408-4) SSB1 [nucleoplasm] (R-SCE-5082380-4) SSB1 [secretory granule lumen] (R-SCE-6801472-4) SSB1 [secretory granule lumen] (R-SCE-6801530-4) SSB1 [extracellular region] (R-SCE-6805936-4) SSB1 [extracellular region] (R-SCE-6806500-4) SSB1 [ficolin-1-rich granule lumen] (R-SCE-6801512-4) SSB1 [ficolin-1-rich granule lumen] (R-SCE-6801494-4) SSB1 [nucleoplasm] (R-SCE-912480-4) SSB1 [nucleoplasm] (R-SCE-5082367-4) SSB1 [nucleoplasm] (R-SCE-5252082-4) SSB1 [nucleoplasm] (R-SCE-5252088-4) SSB1 [nucleoplasm] (R-SCE-5252009-4) SSB1 [nucleoplasm] (R-SCE-5252047-4) SSB1 [cytosol] (R-SCE-5251948-4) SSB1 [cytosol] (R-SCE-5251981-4) SSB1 [cytosol] (R-SCE-3371521-4) SSB1 [cytosol] (R-SCE-5251954-4)	0.527	3
UniProt:P33892 GCN1	1	GCN1 [cytosol] (R-SCE-9633502)	0.527	2
UniProt:P10592	20	SSA2 [cytosol] (R-SCE-264476-3) SSA2 [nucleoplasm] (R-SCE-6792605) SSA2 [cytosol] (R-SCE-3371410-3) SSA2 [cytosol] (R-SCE-3371408-3) SSA2 [cytosol] (R-SCE-6792602) SSA2 [nucleoplasm] (R-SCE-5082380-3) SSA2 [secretory granule lumen] (R-SCE-6801472-3) SSA2 [secretory granule lumen] (R-SCE-6801530-3) SSA2 [extracellular region] (R-SCE-6805936-3) SSA2 [extracellular region] (R-SCE-6806500-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801496) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801512-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801494-3) SSA2 [extracellular region] (R-SCE-6805872) SSA2 [nucleoplasm] (R-SCE-912480-3) SSA2 [nucleoplasm] (R-SCE-5082367-3) SSA2 [nucleoplasm] (R-SCE-5252082-3) SSA2 [nucleoplasm] (R-SCE-5252088-3) SSA2 [nucleoplasm] (R-SCE-5252009-3) SSA2 [nucleoplasm] (R-SCE-5252047-3)	0.527	2
UniProt:P10591	20	SSA1 [cytosol] (R-SCE-264476-2) SSA1 [cytosol] (R-SCE-3371410-2) SSA1 [cytosol] (R-SCE-3371408-2) SSA1 [nucleoplasm] (R-SCE-5082380-2) SSA1 [secretory granule lumen] (R-SCE-6801472-2) SSA1 [secretory granule lumen] (R-SCE-6801530-2) SSA1 [extracellular region] (R-SCE-6805936-2) SSA1 [extracellular region] (R-SCE-6806500-2) SSA1 [ficolin-1-rich granule lumen] (R-SCE-6801512-2) SSA1 [ficolin-1-rich granule lumen] (R-SCE-6801494-2) SSA1 [nucleoplasm] (R-SCE-912480-2) SSA1 [nucleoplasm] (R-SCE-5082367-2) SSA1 [nucleoplasm] (R-SCE-5252082-2) SSA1 [nucleoplasm] (R-SCE-5252088-2) SSA1 [nucleoplasm] (R-SCE-5252009-2) SSA1 [nucleoplasm] (R-SCE-5252047-2) SSA1 [cytosol] (R-SCE-5251948-2) SSA1 [cytosol] (R-SCE-5251981-2) SSA1 [cytosol] (R-SCE-3371521-2) SSA1 [cytosol] (R-SCE-5251954-2)	0.527	2
UniProt:Q03768	1	GIR2 [cytosol] (R-SCE-9629568)	0.527	2
UniProt:P40469 MET18	1	MET18 [cytosol] (R-SCE-2564782)	0.527	2
UniProt:P15180	2	phospho-KRS1 [nucleoplasm] (R-SCE-9825687) phospho-KRS1 [cytosol] (R-SCE-9825686)	0.527	3
UniProt:P22943 HSP12			0.527	2
UniProt:P35191 MDJ1			0.527	2
UniProt:P25454	2	RAD51 [nucleoplasm] (R-SCE-62637) phospho-RAD51 [nucleoplasm] (R-SCE-5685231)	0.527	2
UniProt:P20484 MAK11			0.527	2
UniProt:P53883	2	phospho-NOP13 [cytosol] (R-SCE-165773-2) NOP13 [cytosol] (R-SCE-72589-2)	0.527	3
UniProt:P25694 CDC48	8	CDC48 [cytosol] (R-SCE-1181251) CDC48 [azurophil granule lumen] (R-SCE-6800438) CDC48 [extracellular region] (R-SCE-6806191) CDC48 [secretory granule lumen] (R-SCE-6801039) CDC48 [ficolin-1-rich granule lumen] (R-SCE-6800425) CDC48 [nucleoplasm] (R-SCE-5643745) CDC48 [cytosol] (R-SCE-8932209) CDC48 [cytosol] (R-SCE-9950047)	0.527	2
UniProt:Q05022 RRP5	2	RRP5 [nucleoplasm] (R-SCE-6790686) RRP5 [nucleoplasm] (R-SCE-6790646)	0.527	2
UniProt:Q00362	2	CDC55 [cytosol] (R-SCE-377253) CDC55 [nucleoplasm] (R-SCE-1564978)	0.527	3
UniProt:P39743 RV167			0.527	3
UniProt:P16862	5	PFK2 [ficolin-1-rich granule lumen] (R-SCE-6801030-2) PFK2 [extracellular region] (R-SCE-6806471-2) PFK2 [secretory granule lumen] (R-SCE-6800876-2) PFK2 [cytosol] (R-SCE-71452-2) PFK2 [cytosol] (R-SCE-70459-2)	0.527	2
UniProt:Q12055	1	FAP7 [nucleoplasm] (R-SCE-6788786)	0.527	2
UniProt:P25303 SCJ1			0.527	2
UniProt:Q08004 BUD20			0.527	3
UniProt:P39935	2	phospho-TIF4631 [cytosol] (R-SCE-165762) TIF4631 [cytosol] (R-SCE-72584)	0.527	2
UniProt:P32589	5	SSE1 [nucleoplasm] (R-SCE-5252053) SSE1 [nucleoplasm] (R-SCE-5251998) SSE1 [cytosol] (R-SCE-5251943) SSE1 [cytosol] (R-SCE-5251946) SSE1 [cytosol] (R-SCE-3299412)	0.527	3
UniProt:P38219	2	OLA1 [extracellular region] (R-SCE-8863004) OLA1 [platelet alpha granule lumen] (R-SCE-8862978)	0.508	2
UniProt:P43573 BUD27			0.508	2
UniProt:Q05040	1	FAR8 [cytosol] (R-SCE-9037081)	0.499	2

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