Reactome | CDC53 [cytosol]

CDC53 [cytosol]

Stable Identifier

R-SCE-8952519

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

G76-NEDD8-K720-CUL1, Q12018

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q12018

Gene Names

CDC53

Reference Genes

BioGPS Gene:851424 CDC53

ENSEMBL:YDL132W

KEGG Gene (Saccharomyces cerevisiae (strain YJM789)):YDL132W CDC53

Monarch:851424 CDC53

NCBI Gene:851424 CDC53

SGD:YDL132W

Reference Transcript

RefSeq:NM_001180191.1 CDC53

Other Identifiers

1779631_at

6596_at

851424

GO:0000082

GO:0000086

GO:0000278

GO:0003674

GO:0003677

GO:0003688

GO:0005575

GO:0005634

GO:0005737

GO:0006511

GO:0008150

GO:0019005

GO:0019899

GO:0030674

GO:0031146

GO:0031461

GO:0031625

GO:0042787

GO:0051301

GO:0051603

Participant Of

hasComponent

NEDD8-CUL1 [cytosol]

Other forms of this molecule

CDC53 [cytosol]

CDC53 [nucleoplasm]

CDC53 [cytosol]

Inferred From

G76-NEDD8-K720-CUL1 [cytosol] (Homo sapiens)

Modified Residues

Name

Inter-chain Crosslink via neddylated lysine at 720 and 76 (in Homo sapiens)

Coordinate

720

Modification

glycyl group

PsiMod Name

neddylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a nedd8 protein.

Cross References

RefSeq

NP_010150.1

PRO

Q12018

PDB

3O6B, 3O2P

Interactors (18)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P52286	2	SKP1 [nucleoplasm] (R-SCE-187538) SKP1 [cytosol] (R-SCE-174150)	0.914	15
UniProt:Q08273	3	HRT1 [cytosol] (R-SCE-180582) HRT1 [cytosol] (R-SCE-8863132) HRT1 [nucleoplasm] (R-SCE-1234142)	0.899	9
UniProt:P39014 MET30			0.857	10
UniProt:P24814	1	GRR1 [mitochondrial inner membrane] (R-SCE-5215992)	0.836	9
UniProt:P38352 SAF1			0.816	7
UniProt:Q92325 LAG2			0.727	10
UniProt:P07834 CDC4			0.67	8
UniProt:Q04511	1	UFO1 [cytosol] (R-SCE-391305)	0.643	3
UniProt:Q06479	7	FBXL15 [cytosol] (R-SCE-8862625) FBXL20 [cytosol] (R-SCE-8862591) FBXL13 [cytosol] (R-SCE-8862616) FBXL14 [cytosol] (R-SCE-8862603) FBXL4 [cytosol] (R-SCE-8850899) FBXL7 [cytosol] (R-SCE-8854032) PolyUb-K109-FBXL7 [cytosol] (R-SCE-8854053)	0.643	4
UniProt:P14682	1	CDC34 [cytosol] (R-SCE-947627)	0.641	37
UniProt:Q06150 BOP2			0.547	2
UniProt:Q12395	3	DCN1 [cytosol] (R-SCE-8951782) DCN1 [plasma membrane] (R-SCE-8956204) DCN1 [cytosol] (R-SCE-8951781)	0.547	3
UniProt:P09232	3	PRB1 [lysosomal membrane] (R-SCE-8855128) PRB1 [endolysosome membrane] (R-SCE-6784823) PRB1 [extracellular region] (R-SCE-6784727)	0.527	2
UniProt:Q06640 YD306			0.527	2
UniProt:P47005 DAS1			0.527	2
UniProt:P09435	23	SSA3 [cytosol] (R-SCE-6792602) SSA3 [nucleoplasm] (R-SCE-8932217) SSA3 [cytosol] (R-SCE-5251954) SSA3 [cytosol] (R-SCE-3371521) SSA3 [cytosol] (R-SCE-3371408) SSA3 [cytosol] (R-SCE-5251948) SSA3 [cytosol] (R-SCE-3371410) SSA3 [nucleoplasm] (R-SCE-5252047) SSA3 [nucleoplasm] (R-SCE-5252088) SSA3 [nucleoplasm] (R-SCE-5252082) SSA3 [nucleoplasm] (R-SCE-6792605) SSA3 [nucleoplasm] (R-SCE-5082367) SSA3 [nucleoplasm] (R-SCE-912480) SSA3 [extracellular region] (R-SCE-6805872) SSA3 [ficolin-1-rich granule lumen] (R-SCE-6801494) SSA3 [ficolin-1-rich granule lumen] (R-SCE-6801496) SSA3 [ficolin-1-rich granule lumen] (R-SCE-6801512) SSA3 [extracellular region] (R-SCE-6805936) SSA3 [extracellular region] (R-SCE-6806500) SSA3 [secretory granule lumen] (R-SCE-6801472) SSA3 [secretory granule lumen] (R-SCE-6801530) SSA3 [nucleoplasm] (R-SCE-5082380) SSA3 [cytosol] (R-SCE-264476)	0.527	2
UniProt:Q12347	1	HRT3 [cytosol] (R-SCE-8862608)	0.527	2
UniProt:Q03919	8	RUB1 [cytosol] (R-SCE-6782654) RUB1 [nucleoplasm] (R-SCE-8952504) RUB1 [cytosol] (R-SCE-5690794) RUB1 [cytosol] (R-SCE-8951647) RUB1 [cytosol] (R-SCE-8951739) RUB1 [cytosol] (R-SCE-8952534) RUB1 [cytosol] (R-SCE-416969) RUB1 [cytosol] (R-SCE-4419895)	0.527	2

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